Search Results - "Erickson, Sven"
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1
Effects of GABA agonists on body temperature regulation in GABAB(1)−/− mice
Published in British journal of pharmacology (01-09-2003)“…Activation of GABAB receptors evokes hypothermia in wildtype (GABAB(1)+/+) but not in GABAB receptor knockout (GABAB(1)−/−) mice. The aim of the present study…”
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2
Effects of GABA agonists on body temperature regulation in GABA-/-B(1) mice
Published in British journal of pharmacology (02-02-2009)“…Activation of GABA B receptors evokes hypothermia in wildtype ( GABA B(1) +/+ ) but not in GABA B receptor knockout ( GABA B(1) −/− ) mice. The aim of the…”
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3
Joseph G. Gavin, Jr. and MIT’s contribution to aerospace in the Apollo era and beyond
Published in Acta astronautica (01-04-2021)“…Five decades after the Apollo 11 moonlanding, it is time to consider the individuals and institutions that made it possible. Examining the remarkable aerospace…”
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4
Mechanisms of interferon-alpha induced apoptosis in malignant cells
Published in Oncogene (14-02-2002)“…Interferon alpha (IFNalpha) has been used in the treatment of several types of cancer for almost 30 years, yet the mechanism(s) responsible for its…”
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5
Effects of GABA agonists on body temperature regulation in GABA(B(1))-/- mice
Published in British journal of pharmacology (01-09-2003)“…1. Activation of GABA(B) receptors evokes hypothermia in wildtype (GABA(B(1))+/+) but not in GABA(B) receptor knockout (GABA(B(1))-/-) mice. The aim of the…”
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6
Molecular mechanisms underlying interferon-α-induced G0/G1 arrest : CKI-mediated regulation of G1 Cdk-complexes and activation of pocket proteins
Published in Oncogene (06-05-1999)“…One prominent effect of IFNs is their cell growth-inhibitory activity. The mechanism behind this inhibition of proliferation is still not fully understood. In…”
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Interferon α down-regulates telomerase reverse transcriptase and telomerase activity in human malignant and nonmalignant hematopoietic cells
Published in Blood (2000)“…Recently, the derepressed expression of the catalytic subunit of telomerase, human telomerase reverse transcriptase (hTERT), the enzyme that elongates…”
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Induction of Cip/Kip and Ink4 cyclin dependent kinase inhibitors by interferon-α in hematopoietic cell lines
Published in Oncogene (1997)“…One prominent effect of IFNs is their cell growth inhibitory activity. The exact molecular mechanism behind this inhibition of proliferation remains to be…”
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9
Involvement of the Ink4 proteins p16 and p15 in T-lymphocyte senescence
Published in Oncogene (06-08-1998)“…Little is known about the molecular background to senescence in T-lymphocytes. In fibroblast systems replicative senescence has been shown to correlate with a…”
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10
How does interferon exert its cell growth inhibitory effect?
Published in European journal of haematology (01-09-1997)“…: The interferons (IFNs) have become accepted therapy in a range of haematological and non‐haematological malignancies. The mechanism behind IFN's antitumour…”
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Effects of Interferon-α on Cell Cycle Regulatory Proteins in Leukemic Cells
Published in Leukemia & lymphoma (01-01-2003)“…One prominent activity of Interferons (IFNs) is their ability to induce cell cycle arrest, and this effect has furthermore been proposed to be of major…”
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12
Interferon α down-regulates telomerase reverse transcriptase and telomerase activity in human malignant and nonmalignant hematopoietic cells
Published in Blood (15-12-2000)“…Recently, the derepressed expression of the catalytic subunit of telomerase, human telomerase reverse transcriptase (hTERT), the enzyme that elongates…”
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13
Interferon‐alpha inhibits Stat5 DNA‐binding in IL‐2 stimulated primary T‐lymphocytes
Published in European journal of biochemistry (01-01-2002)“…It has previously been shown that IFN‐α is a potent inhibitor of IL‐2 induced proliferation in primary T‐lymphocytes, by selectively abrogating the downstream…”
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14
Induction of apoptosis and inhibition of cell growth are independent responses to interferon-α in hematopoietic cell lines
Published in Cell growth & differentiation (01-03-1997)“…IFNs are capable of modulating a variety of cellular responses, including cell growth and apoptosis. The prospective connections between these two biological…”
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15
Interferon-α inhibits proliferation in human T lymphocytes by abrogation of interleukin 2-induced changes in cell cycle-regulatory proteins
Published in Cell growth & differentiation (01-08-1999)“…IFN-alpha exerts prominent regulatory functions on the immune system. One such effect is the inhibition of proliferation of in vitro stimulated T lymphocytes…”
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