Search Results - "Erich G. Goldbach"
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Discovery of sulfonamide–pyrazole γ-secretase inhibitors
Published in Bioorganic & medicinal chemistry letters (01-04-2010)“…Utilizing a pharmacophore hypothesis, previously described γ-secretase inhibiting HTS hits were evolved into novel tricyclic sulfonamide–pyrazoles, with high…”
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2
A series of C-Terminal amino alcohol dipeptide Aβ inhibitors
Published in Bioorganic & medicinal chemistry letters (04-11-2002)“…Potent, small molecule Aβ inhibitors have been prepared that incorporate an alanine core bracketed by an N-terminal arylacetyl group and various C-terminal…”
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α4β1Integrin-dependent Cell Adhesion Is Regulated by a Low Affinity Receptor Pool That Is Conformationally Responsive to Ligand ()
Published in The Journal of biological chemistry (01-12-1995)“…α4β1 integrin (VLA-4) appears to be unique among the leukocyte integrins in that it can initiate the adhesion of circulating lymphocytes without cellular…”
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4
Integrin-dependent Cell Adhesion Is Regulated by a Low Affinity Receptor Pool That Is Conformationally Responsive to Ligand
Published in The Journal of biological chemistry (01-12-1995)“…α β integrin (VLA-4) appears to be unique among the leukocyte integrins in that it can initiate the adhesion of circulating lymphocytes without cellular…”
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Journal Article