Search Results - "Erica Lazarus"

Review of preventative HIV vaccine clinical trials in South Africa by Laher, Fatima, Bekker, Linda-Gail, Garrett, Nigel, Lazarus, Erica M., Gray, Glenda E.

“…New HIV infections continue relentlessly in southern Africa, demonstrating the need for a vaccine to prevent HIV subtype C. In South Africa, the country with…”
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Immunogenicity of the 9-Valent HPV Vaccine Using 2-Dose Regimens in Girls and Boys vs a 3-Dose Regimen in Women by Iversen, Ole-Erik, Miranda, Maria Jose, Ulied, Angels, Soerdal, Terje, Lazarus, Erica, Chokephaibulkit, Kulkanya, Block, Stan L, Skrivanek, Ales, Nur Azurah, Abdul Ghani, Fong, Siew Moy, Dvorak, Vladimir, Kim, Kyung-Hyo, Cestero, Ramon M, Berkovitch, Matitiahu, Ceyhan, Mehmet, Ellison, Misoo C, Ritter, Michael A, Yuan, Shuai S, DiNubile, Mark J, Saah, Alfred J, Luxembourg, Alain

“…IMPORTANCE: Human papillomavirus (HPV) infections cause anogenital cancers and warts. The 9-valent HPV vaccine provides protection against 7 high-risk types of…”
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Early time-limited antiretroviral therapy versus deferred therapy in South African infants infected with HIV: results from the children with HIV early antiretroviral (CHER) randomised trial by Cotton, Mark F, Prof, Violari, Avy, FCPaed [SA], Otwombe, Kennedy, MSc, Panchia, Ravindre, MB, Dobbels, Els, FCPaed [SA], Rabie, Helena, FCPaed [SA], Josipovic, Deirdre, MB, Liberty, Afaaf, MB, Lazarus, Erica, MB, Innes, Steve, MB, van Rensburg, Anita Janse, Dip Nurs, Pelser, Wilma, RN, Truter, Handre, NDip, Madhi, Shabir A, Prof, Handelsman, Edward, MD, Jean-Philippe, Patrick, MD, McIntyre, James A, Prof, Gibb, Diana M, Prof, Babiker, Abdel G, Prof

“…Summary Background Interim results from the children with HIV early antiretroviral (CHER) trial showed that early antiretroviral therapy (ART) was life-saving…”
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A mixed methods investigation of implementation barriers and facilitators to a daily mobile phone sexual risk assessment for young women in Soweto, South Africa by Dietrich, Janan J, Hornschuh, Stefanie, Khunwane, Mamakiri, Makhale, Lerato M, Otwombe, Kennedy, Morgan, Cecilia, Huang, Yunda, Lemos, Maria, Lazarus, Erica, Kublin, James G, Gray, Glenda E, Laher, Fatima, Andrasik, Michele

“…The HIV epidemiology in South Africa reveals stark age and gender disparities, with young women being the most vulnerable to HIV acquisition in 2017…”
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Longitudinal IgA and IgG Response, and ACE2 Binding Blockade, to Full-Length SARS-CoV-2 Spike Protein Variants in a Population of Black PLWH Vaccinated with ChAdOx1 nCoV-19 by Smith, Muneerah, Kwatra, Gaurav, Izu, Alane, Nel, Andrew, Cutland, Clare, Ahmed, Khatja, Baillie, Vicky, Barnabas, Shaun, Bhorat, Qasim, Briner, Carmen, Lazarus, Erica, Dheda, Keertan, Fairlie, Lee, Koen, Anthonet, Madhi, Shabir, Blackburn, Jonathan M

“…Vaccines against SARS-CoV-2 have been pivotal in overcoming the COVID-19 pandemic yet understanding the subsequent outcomes and immunological effects remain…”
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A Cross Sectional Study of the Prevalence of Preputial and Penile Scrotal Abnormalities among Clients Undergoing Voluntary Medical Male Circumcision in Soweto, South Africa by Mukudu, Hillary, Otwombe, Kennedy, Laher, Fatima, Lazarus, Erica, Manentsa, Mmatsie, Lebina, Limakatso, Mapulanga, Victor, Bowa, Kasonde, Martinson, Neil

“…Medical device use is currently approved for males without preputial or major penile scrotal abnormalities for voluntary medical male circumcision (VMMC). We…”
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A retrospective case-cohort study comparing treatment outcomes in abacavir versus stavudine containing first line antiretroviral treatment regimens in children <3yrs old, at a paediatric programme based in Soweto, South Africa by Cassim, Haseena, Otwombe, Kennedy, Lazarus, Erica, Liberty, Afaaf, Gray, Glenda E, Greeff, Oppel B W, Violari, Avy

“…The current World Health Organization guideline for first line antiretroviral therapy (ART) in HIV-infected children recommends the use of abacavir and…”
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Early severe HIV disease precedes early antiretroviral therapy in infants: Are we too late? by Innes, Steve, Lazarus, Erica, Otwombe, Kennedy, Liberty, Afaaf, Germanus, Ramona, Van Rensburg, Anita Janse, Grobbelaar, Nelis, Hurter, Theunis, Eley, Brian, Violari, Avy, Cotton, Mark F

“…Objective To describe the degree of HIV disease progression in infants initiating antiretroviral therapy (ART) by three months of age in a programmatic setting…”
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Uptake of genital mucosal sampling in HVTN 097, a phase 1b HIV vaccine trial in South Africa by Lazarus, Erica Maxine, Otwombe, Kennedy, Adonis, Tania, Sebastian, Elaine, Gray, Glenda, Grunenberg, Nicole, Roux, Surita, Churchyard, Gavin, Innes, Craig, Laher, Fatima

“…Because sexual transmission of HIV occurs across mucosal membranes, understanding the immune responses of the genital mucosa to vaccines may contribute…”
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Pharmacokinetics and predicted neutralisation coverage of VRC01 in HIV-uninfected participants of the Antibody Mediated Prevention (AMP) trials by Huang, Yunda, Naidoo, Logashvari, Zhang, Lily, Carpp, Lindsay N., Rudnicki, Erika, Randhawa, April, Gonzales, Pedro, McDermott, Adrian, Ledgerwood, Julie, Lorenzo, Margarita M.Gomez, Burns, David, DeCamp, Allan, Juraska, Michal, Mascola, John, Edupuganti, Srilatha, Mgodi, Nyaradzo, Cohen, Myron, Corey, Lawrence, Andrew, Philip, Karuna, Shelly, Gilbert, Peter B., Mngadi, Kathryn, Lazarus, Erica

“…The phase 2b AMP trials are testing whether the broadly neutralising antibody VRC01 prevents HIV-1 infection in two cohorts: women in sub-Saharan Africa, and…”
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Safety and immunogenicity of booster vaccination and fractional dosing with Ad26.COV2.S or BNT162b2 in Ad26.COV2.S-vaccinated participants by Riou, Catherine, Bhiman, Jinal N, Ganga, Yashica, Sawry, Shobna, Ayres, Frances, Baguma, Richard, Balla, Sashkia R, Benede, Ntombi, Bernstein, Mallory, Besethi, Asiphe S, Cele, Sandile, Crowther, Carol, Dhar, Mrinmayee, Geyer, Sohair, Gill, Katherine, Grifoni, Alba, Hermanus, Tandile, Kaldine, Haajira, Keeton, Roanne S, Kgagudi, Prudence, Khan, Khadija, Lazarus, Erica, Le Roux, Jean, Lustig, Gila, Madzivhandila, Mashudu, Magugu, Siyabulela F J, Makhado, Zanele, Manamela, Nelia P, Mkhize, Qiniso, Mosala, Paballo, Motlou, Thopisang P, Mutavhatsindi, Hygon, Mzindle, Nonkululeko B, Nana, Anusha, Nesamari, Rofhiwa, Ngomti, Amkele, Nkayi, Anathi A, Nkosi, Thandeka P, Omondi, Millicent A, Panchia, Ravindre, Patel, Faeezah, Sette, Alessandro, Singh, Upasna, van Graan, Strauss, Venter, Elizabeth M, Walters, Avril, Moyo-Gwete, Thandeka, Richardson, Simone I, Garrett, Nigel, Rees, Helen, Bekker, Linda-Gail, Gray, Glenda, Burgers, Wendy A, Sigal, Alex, Moore, Penny L, Fairlie, Lee

“…We report the safety and immunogenicity of fractional and full dose Ad26.COV2.S and BNT162b2 in an open label phase 2 trial of participants previously…”
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“You Are on the Right Track With the App:” Qualitative Analysis of Mobile Phone Use and User Feedback Regarding Mobile Phone Sexual Risk Assessments for HIV Prevention Research by Dietrich, Janan J., Benadé, Gabriella L., Mulaudzi, Mamakiri, Kagee, Ashraf, Hornschuh, Stefanie, Makhale, Lerato M., Lemos, Maria P., Lazarus, Erica, Andrasik, Michele P., Horvath, Keith J.

“…Background: Accurate self-report of sexual behavior assists in identifying potential HIV exposure in HIV prevention trials. Brief mobile phone assessments,…”
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Vaginal practices among women at risk for HIV acquisition in Soweto, South Africa by Andrasik, Michele P., Morgan, Cecilia A., Isaacs, Abby J., Kublin, James G., Lazarus, Erica, Dietrich, Janan, Gray, Glenda E., Otwombe, Kennedy, Laher, Fatima

“…Background: Vaginal practices (VP) may adversely affect normal vaginal flora and mucosal integrity, and increase acquisition risk of HIV and other genital…”
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Sexually transmitted infections amongst men who have sex with men (MSM) in South Africa by Mashingaidze, Rujeko, Moodie, Zoe, Allen, Mary, Bekker, Linda-Gail, Grove, Doug, Grunenberg, Nicole, Huang, Yunda, Janes, Holly E, Lazarus, Erica Maxine, Malahleha, Mookho, Nchabeleng, Maphoshane, Laher, Fatima

“…There is limited data about bacterial STIs in MSM populations in sub-Saharan Africa. Our retrospective analysis used data from the HVTN 702 HIV vaccine…”
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Held to Ransom: CMV Treatment in South Africa by Laher, Fatima, Ashford, Gail, Cescon, Angela, Cullen, Claire, Lazarus, Erica, Puren, Adrian, Visser, Linda

“…Cytomegalovirus is a multi-systemic infection reactivated in the immunocompromised. Diagnosis and treatment are prohibitively costly in sub-Saharan Africa, and…”
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Neonatal Cryptococcosis: Beware of False-positive Results by Soni, Zaheera J., Reubenson, Gary, De Maayer, Tim, Coovadia, Ashraf, Lazarus, Erica M.

“…Although cryptococcal meningitis is uncommon in children and rare in neonates, it does occur. We highlight circumstances in which the diagnosis should be…”
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Two Randomized Trials of Neutralizing Antibodies to Prevent HIV-1 Acquisition by Corey, Lawrence, Gilbert, Peter B, Juraska, Michal, Montefiori, David C, Morris, Lynn, Karuna, Shelly T, Edupuganti, Srilatha, Mgodi, Nyaradzo M, deCamp, Allan C, Rudnicki, Erika, Huang, Yunda, Gonzales, Pedro, Cabello, Robinson, Orrell, Catherine, Lama, Javier R, Laher, Fatima, Lazarus, Erica M, Sanchez, Jorge, Frank, Ian, Hinojosa, Juan, Sobieszczyk, Magdalena E, Marshall, Kyle E, Mukwekwerere, Pamela G, Makhema, Joseph, Baden, Lindsey R, Mullins, James I, Williamson, Carolyn, Hural, John, McElrath, M. Juliana, Bentley, Carter, Takuva, Simbarashe, Gomez Lorenzo, Margarita M, Burns, David N, Espy, Nicole, Randhawa, April K, Kochar, Nidhi, Piwowar-Manning, Estelle, Donnell, Deborah J, Sista, Nirupama, Andrew, Philip, Kublin, James G, Gray, Glenda, Ledgerwood, Julie E, Mascola, John R, Cohen, Myron S

“…Two phase 2 trials assessed the efficacy and safety of intravenous infusions of a broadly neutralizing antibody, VRCO1, to prevent HIV-1 infection. VRC01 did…”
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Evaluation of a mosaic HIV-1 vaccine in a multicentre, randomised, double-blind, placebo-controlled, phase 1/2a clinical trial (APPROACH) and in rhesus monkeys (NHP 13-19) by Barouch, Dan H, Tomaka, Frank L, Wegmann, Frank, Stieh, Daniel J, Alter, Galit, Robb, Merlin L, Michael, Nelson L, Peter, Lauren, Nkolola, Joseph P, Borducchi, Erica N, Chandrashekar, Abishek, Jetton, David, Stephenson, Kathryn E, Li, Wenjun, Korber, Bette, Tomaras, Georgia D, Montefiori, David C, Gray, Glenda, Frahm, Nicole, McElrath, M Juliana, Baden, Lindsey, Johnson, Jennifer, Hutter, Julia, Swann, Edith, Karita, Etienne, Kibuuka, Hannah, Mpendo, Juliet, Garrett, Nigel, Mngadi, Kathy, Chinyenze, Kundai, Priddy, Frances, Lazarus, Erica, Laher, Fatima, Nitayapan, Sorachai, Pitisuttithum, Punnee, Bart, Stephan, Campbell, Thomas, Feldman, Robert, Lucksinger, Gregg, Borremans, Caroline, Callewaert, Katleen, Roten, Raphaele, Sadoff, Jerald, Scheppler, Lorenz, Weijtens, Mo, Feddes-de Boer, Karin, van Manen, Daniëlle, Vreugdenhil, Jessica, Zahn, Roland, Lavreys, Ludo, Nijs, Steven, Tolboom, Jeroen, Hendriks, Jenny, Euler, Zelda, Pau, Maria G, Schuitemaker, Hanneke

“…More than 1·8 million new cases of HIV-1 infection were diagnosed worldwide in 2016. No licensed prophylactic HIV-1 vaccine exists. A major limitation to date…”
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Approaches to preventative and therapeutic HIV vaccines by Gray, Glenda E, Laher, Fatima, Lazarus, Erica, Ensoli, Barbara, Corey, Lawrence

“…•Non-efficacious preventative vaccines: gp120, Ad5 vector, DNA/Ad5.•Partially-efficacious preventative vaccine: ALVAC-HIV/AIDSVAX® B/E gp120.•Clade C…”
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Effectiveness of the Ad26.COV2.S vaccine in health-care workers in South Africa (the Sisonke study): results from a single-arm, open-label, phase 3B, implementation study by Bekker, Linda-Gail, Garrett, Nigel, Goga, Ameena, Fairall, Lara, Reddy, Tarylee, Yende-Zuma, Nonhlanhla, Kassanjee, Reshma, Collie, Shirley, Sanne, Ian, Boulle, Andrew, Seocharan, Ishen, Engelbrecht, Imke, Davies, Mary-Ann, Champion, Jared, Chen, Tommy, Bennett, Sarah, Mametja, Selaelo, Semenya, Mabatlo, Moultrie, Harry, de Oliveira, Tulio, Lessells, Richard John, Cohen, Cheryl, Jassat, Waasila, Groome, Michelle, Von Gottberg, Anne, Le Roux, Engelbert, Khuto, Kentse, Barouch, Dan, Mahomed, Hassan, Wolmarans, Milani, Rousseau, Petro, Bradshaw, Debbie, Mulder, Michelle, Opie, Jessica, Louw, Vernon, Jacobson, Barry, Rowji, Pradeep, Peter, Jonny G, Takalani, Azwi, Odhiambo, Jackline, Mayat, Fatima, Takuva, Simbarashe, Corey, Lawrence, Gray, Glenda E, Brumskine, William, Naicker, Nivashnee, Makhaza, Disebo, Naicker, Vimla, Naidoo, Logashvari, Spooner, Elizabeth, van Nieuwenhuizen, Elane, Mngadi, Kathryn, Nchabeleng, Maphoshane, Innes, James Craig, Gill, Katherine, Petrick, Friedrich Georg, Barnabas, Shaun, Badal-Faesen, Sharlaa, Kassim, Sheetal, Mahoney, Scott Hayden, Lazarus, Erica, Nana, Anusha, Maboa, Rebone Molobane, Kotze, Philip, Lombaard, Johan, Malan, Daniel Rudolf, Kotze, Sheena, Mohlala, Phuthi, Ward, Amy, Meintjes, Graeme, Urbach, Dorothea, Patel, Faeezah, Diacon, Andreas, Ahmed, Khatija, Grobbelaar, Coert, Mda, Pamela, Dubula, Thozama, Luabeya, Angelique, Mamba, Musawenkosi Bhekithemba, Burgess, Lesley, Dawson, Rodney

“…We aimed to assess the effectiveness of a single dose of the Ad26.COV2.S vaccine (Johnson & Johnson) in health-care workers in South Africa during two waves of…”
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