Search Results - "Eric Deutsch"
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GHOST: Graph-based higher-order similarity transformation for classification
Published in Pattern recognition (01-11-2024)“…Exploring and identifying a good feature representation to describe high-dimensional datasets is a challenge of prime importance. However, plenty of feature…”
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Optimising efficacy and reducing toxicity of anticancer radioimmunotherapy
Published in The lancet oncology (01-08-2019)“…SummaryImmunotherapy is radically changing the clinical management of patients affected by an increasingly wide array of tumours. However, not all patients…”
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File Formats Commonly Used in Mass Spectrometry Proteomics
Published in Molecular & cellular proteomics (01-12-2012)“…The application of mass spectrometry (MS) to the analysis of proteomes has enabled the high-throughput identification and abundance measurement of hundreds to…”
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Radiotherapy–immunotherapy combinations – perspectives and challenges
Published in Molecular oncology (01-07-2020)“…Ionizing radiation has historically been used to treat cancer by killing tumour cells, in particular by inducing DNA damage. This view of radiotherapy (RT) as…”
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The ProteomeXchange consortium in 2020: enabling ‘big data’ approaches in proteomics
Published in Nucleic acids research (08-01-2020)“…Abstract The ProteomeXchange (PX) consortium of proteomics resources (http://www.proteomexchange.org) has standardized data submission and dissemination of…”
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The ProteomeXchange consortium at 10 years: 2023 update
Published in Nucleic acids research (06-01-2023)“…Mass spectrometry (MS) is by far the most used experimental approach in high-throughput proteomics. The ProteomeXchange (PX) consortium of proteomics resources…”
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The ProteomeXchange consortium in 2017: supporting the cultural change in proteomics public data deposition
Published in Nucleic acids research (04-01-2017)“…The ProteomeXchange (PX) Consortium of proteomics resources (http://www.proteomexchange.org) was formally started in 2011 to standardize data submission and…”
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PeptideAtlas: a resource for target selection for emerging targeted proteomics workflows
Published in EMBO reports (01-05-2008)“…A crucial part of a successful systems biology experiment is an assay that provides reliable, quantitative measurements for each of the components in the…”
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The PeptideAtlas Project
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2010)“…PeptideAtlas is a multi-species compendium of peptides observed with tandem mass spectrometry methods. Raw mass spectrometer output files are collected from…”
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ProteomeXchange provides globally coordinated proteomics data submission and dissemination
Published in Nature biotechnology (01-03-2014)Get full text
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Trans-Proteomic Pipeline, a standardized data processing pipeline for large-scale reproducible proteomics informatics
Published in Proteomics. Clinical applications (01-08-2015)“…Democratization of genomics technologies has enabled the rapid determination of genotypes. More recently the democratization of comprehensive proteomics…”
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Extending Comet for Global Amino Acid Variant and Post‐Translational Modification Analysis Using the PSI Extended FASTA Format
Published in Proteomics (Weinheim) (01-11-2020)“…Protein identification by tandem mass spectrometry sequence database searching is a standard practice in many proteomics laboratories. The de facto standard…”
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A cross-platform toolkit for mass spectrometry and proteomics
Published in Nature biotechnology (01-10-2012)“…Mass-spectrometry-based proteomics has become an important component of biological research. Numerous proteomics methods have been developed to identify and…”
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Gut microbiome influences efficacy of PD-1-based immunotherapy against epithelial tumors
Published in Science (American Association for the Advancement of Science) (05-01-2018)“…Immune checkpoint inhibitors (ICIs) targeting the PD-1/PD-L1 axis induce sustained clinical responses in a sizable minority of cancer patients. We found that…”
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iProphet: Multi-level Integrative Analysis of Shotgun Proteomic Data Improves Peptide and Protein Identification Rates and Error Estimates
Published in Molecular & cellular proteomics (01-12-2011)“…The combination of tandem mass spectrometry and sequence database searching is the method of choice for the identification of peptides and the mapping of…”
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Combining Results of Multiple Search Engines in Proteomics
Published in Molecular & cellular proteomics (01-09-2013)“…A crucial component of the analysis of shotgun proteomics datasets is the search engine, an algorithm that attempts to identify the peptide sequence from the…”
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SpectiCal: m/z Calibration of MS2 Peptide Spectra Using Known Low Mass Ions
Published in Journal of proteome research (05-04-2024)“…Most tandem mass spectrometry fragmentation spectra have small calibration errors that can lead to suboptimal interpretation and annotation. We developed…”
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Predictive Big Data Analytics: A Study of Parkinson's Disease Using Large, Complex, Heterogeneous, Incongruent, Multi-Source and Incomplete Observations
Published in PloS one (05-08-2016)“…A unique archive of Big Data on Parkinson's Disease is collected, managed and disseminated by the Parkinson's Progression Markers Initiative (PPMI). The…”
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The Human Immunopeptidome Project: A Roadmap to Predict and Treat Immune Diseases
Published in Molecular & cellular proteomics (01-01-2020)“…Immunopeptidomics is a rapidly evolving field that is catalyzed by neoantigen discovery and cancer immunotherapy. Emulating the path of other omic disciplines,…”
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Brachytherapy: An overview for clinicians
Published in CA: a cancer journal for clinicians (01-09-2019)“…Brachytherapy is a specific form of radiotherapy consisting of the precise placement of radioactive sources directly into or next to the tumor. This technique…”
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