Search Results - "Eric D Scheeff"

Structure of the Pseudokinase VRK3 Reveals a Degraded Catalytic Site, a Highly Conserved Kinase Fold, and a Putative Regulatory Binding Site by Scheeff, Eric D., Eswaran, Jeyanthy, Bunkoczi, Gabor, Knapp, Stefan, Manning, Gerard

“…About 10% of all protein kinases are predicted to be enzymatically inactive pseudokinases, but the structural details of kinase inactivation have remained…”
Get full text

Short Promoters in Viral Vectors Drive Selective Expression in Mammalian Inhibitory Neurons, but do not Restrict Activity to Specific Inhibitory Cell-Types by Nathanson, Jason L, Jappelli, Roberto, Scheeff, Eric D, Manning, Gerard, Obata, Kunihiko, Brenner, Sydney, Callaway, Edward M

“…Short cell-type specific promoter sequences are important for targeted gene therapy and studies of brain circuitry. We report on the ability of short promoter…”
Get full text

Application of protein structure alignments to iterated hidden Markov model protocols for structure prediction by Scheeff, Eric D, Bourne, Philip E

“…One of the most powerful methods for the prediction of protein structure from sequence information alone is the iterative construction of profile-type models…”
Get full text

Structural evolution of the protein kinase-like superfamily by Scheeff, Eric D, Bourne, Philip E

“…The protein kinase family is large and important, but it is only one family in a larger superfamily of homologous kinases that phosphorylate a variety of…”
Get full text

CE-MC: a multiple protein structure alignment server by Guda, Chittibabu, Lu, Sifang, Scheeff, Eric D., Bourne, Philip E., Shindyalov, Ilya N.

“…CE-MC server (http://cemc.sdsc.edu) provides a web-based facility for the alignment of multiple protein structures based on C-α coordinate distances, using…”
Get full text

Genomics, evolution, and crystal structure of a new family of bacterial spore kinases by Scheeff, Eric D., Axelrod, Herbert L., Miller, Mitchell D., Chiu, Hsiu-Ju, Deacon, Ashley M., Wilson, Ian A., Manning, Gerard

“…Bacterial spore formation is a complex process of fundamental relevance to biology and human disease. The spore coat structure is complex and poorly…”
Get full text

Molecular modeling of the intrastrand guanine-guanine DNA adducts produced by cisplatin and oxaliplatin by Scheeff, E D, Briggs, J M, Howell, S B

“…Intrastrand DNA adducts formed by cisplatin and oxaliplatin were modeled with molecular mechanics minimization and restrained molecular dynamics simulations in…”
Get more information

Con-Struct Map: a comparative contact map analysis tool by Chung, Jo-Lan, Beaver, John E., Scheeff, Eric D., Bourne, Philip E.

“…Con-Struct Map is a graphical tool for the comparative study of protein structures. The tool detects potential conserved residue contacts shared by multiple…”
Get full text

Fundamentals of protein structure by Scheeff, Eric D, Fink, J Lynn

Get more information

Structural evolution of the protein kinase-like superfamily by Eric D Scheeff, Philip E Bourne

“…The protein kinase family is large and important, but it is only one family in a larger superfamily of homologous kinases that phosphorylate a variety of…”
Get full text

Nucleic acids by Murray-Rust, Judith, Lakey, Jeremy H, Scheeff, Eric D

Get full text

Nucleic acids: Sequences and topology by Murray-Rust, Judith, Lakey, Jeremy H, Scheeff, Eric D

“…A selection of World Wide Web sites relevant to reviews published in this issue of Current Opinion in Structural Biology…”
Get full text