Risk factors and microbiology of wound infections following cesarean delivery: Experience of a single institution

Abstract Aims To determine the prevalence of wound infection following cesarean delivery, risk factors, common bacterial pathogens and their antibiotic sensitivity. Material-method The study population consisted of 5787 cesarean deliveries. All of the patients received 2 g doses of cephazolin periop...

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Bibliographic Details
Published in:	Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy Vol. 22; no. 10; pp. 667 - 670
Main Authors:	ilhan, Gülşah, Verit Atmaca, Fatma Ferda, Kaya, Abdurrahman, Ergin, Ahmet Hasan, Gökmen Karasu, Ayşe Filiz, Turfan, Mehtap
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier Ltd 01-10-2016
Subjects:	Abdomen Adult Anti-Bacterial Agents - administration & dosage Anti-Bacterial Agents - therapeutic use Antibiotic Prophylaxis Cefazolin - administration & dosage Cefazolin - therapeutic use Cefuroxime - administration & dosage Cefuroxime - therapeutic use Cesarean Cesarean Section - adverse effects Enterococcus - isolation & purification Escherichia coli - isolation & purification Escherichia coli Infections - epidemiology Escherichia coli Infections - microbiology Escherichia coli Infections - prevention & control Female Hematology, Oncology and Palliative Medicine Humans Incidence Pregnancy Prevalence Prophylaxis Risk Factors Staphylococcal Infections - epidemiology Staphylococcal Infections - microbiology Staphylococcal Infections - prevention & control Staphylococcus - isolation & purification Surgical Wound Infection - epidemiology Surgical Wound Infection - microbiology Surgical Wound Infection - prevention & control Treatment Outcome Wound infection Young Adult Wound infection Cesarean Prophylaxis
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Summary:	Abstract Aims To determine the prevalence of wound infection following cesarean delivery, risk factors, common bacterial pathogens and their antibiotic sensitivity. Material-method The study population consisted of 5787 cesarean deliveries. All of the patients received 2 g doses of cephazolin perioperatively for antibiotic prophylaxis. Patients with wound infection who had two doses of 1 g cephazolin postoperatively and who were continued on oral preparations of 500 mg of cephuroxime twice daily for 5 days after hospital discharge were included in Group A. Patients with wound infection whose postoperative antibiotics and antibiotics after discharge were omitted were included in Group B. Patient related variables, gestational age, co-morbidities, cesarean section indications, neonatal intensive care requirements were assessed. Risk factors were evaluated according to the type of the procedure (elective or emergent) and administered antibiotic protocol. Results The incidence of wound infection following cesarean section was 0,37% in elective operations and 5,4% in emergency cases. On the other hand, wound infection rate was found to be 1,35% in antibiotic receiving group (Group A) and 1,12% in the group not receiving antibiotics (Group B). Conclusion Increased rate of wound infections were remarkable in emergency cases and postoperative antibiotics did not have a major impact in reducing the rate of wound infection following cesarean section.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1341-321X 1437-7780
DOI:	10.1016/j.jiac.2016.07.001