Search Results - "Erfani, Mehran"
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Antioxidative and antidiabetic effects of Capparis spinosa fruit extract on high-fat diet and low-dose streptozotocin-induced type 2 diabetic rats
Published in Biomedicine & pharmacotherapy (01-06-2021)“…Capparis spinosa (CS) is known as a hypoglycemic medication in many countries. This study was designed to reveal the protective effects of the hydro-ethanolic…”
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ARID1A regulates E-cadherin expression in colorectal cancer cells: a promising candidate therapeutic target
Published in Molecular biology reports (01-10-2021)“…Background Metastasis is a major cause of death in Colorectal cancer (CRC) patients, and the Epithelial–mesenchymal transition (EMT) has been known to be a…”
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The effect of curcumin on serum copper, zinc, and zinc/copper ratio in patients with β-thalassemia intermedia: a randomized double-blind clinical trial
Published in Annals of hematology (01-03-2021)“…Thalassemia intermedia is a subgroup of β-thalassemia which originates from mutations in the beta-globin gene. Zinc and copper play important roles in the…”
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Altered ARID1A expression in colorectal cancer
Published in BMC cancer (25-04-2020)“…ARID1A has been described as a tumor suppressor gene, participating in chromatin re-modeling, epithelial-mesenchymal-transition and many other cellular and…”
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Endoplasmic reticulum Metallo protease 1, a triggering factor for unfolded protein response and promising target in colorectal cancer
Published in Biológia (01-08-2021)“…Unfolded protein response (UPR) pathway is a promising target for cancer treatment because of its over-activation in different cancers and its role in…”
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Identifying a Novel Pathogenic Mutation in Exon 3 of ARID1A Gene in Colon Cancer
Published in Middle East journal of cancer (01-04-2020)“…ARID1A, a bona fide tumor suppressor, is the third most mutated gene in human colorectal cancer. In this paper, we reported the identification of a novel…”
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Modulation of TNF-α plasma levels in coronary artery disease [CAD] and non-CAD male patients by lncRNA UCA1 and aspirin
Published in Archives of biological sciences (2020)“…The aim of this study was to investigate the expression of long non-coding RNA urothelial carcinoma-associated 1 (UCA1) and its role in TNF-? production as one…”
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An overview of the biological and multifunctional roles of IL-38 in different infectious diseases and COVID-19
Published in Immunologic research (01-06-2022)“…Undoubtfully, the normal immune system can make a potential response to variable pathogens and neutralize or kill them depending on the type of infection…”
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Examining the expression of low-density lipoprotein receptor ( LDLR ) and low-density lipoprotein receptor-related protein 6 ( LRP6 ) genes in breast cancer cell lines
Published in Molecular biology research communications (01-01-2024)“…Cholesterol and the Wnt/β-catenin pathway have an effective role in the proliferation, survival, drug resistance, immune exhaustion, and metastasis of all…”
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Evidence of histone modification affecting ARID1A expression in colorectal cancer cell lines
Published in Gastroenterology and hepatology from bed to bench (2022)“…The current study aimed to focus on the role of histone deacetylation in reduced expression in colorectal cancer cell lines. ARID1A, a subunit of the…”
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The Effect of Curcumin on Iron Overload in Patients with Beta-Thalassemia Intermedia
Published in Clinical laboratory (Heidelberg) (01-01-2022)“…β-thalassemia is an inherited disorder that stems from a defect in beta-globin chain synthesis. Iron overload toxicity is one of the major clinical…”
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BDNF Val66Met genetic variation and its plasma level in patients with morbid obesity: A case-control study
Published in Gene (15-07-2019)“…Obesity is a major public health concern worldwide. Genetic, behavioral, and environmental factors contribute to the multifactorial etiology of obesity…”
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Suppression of Growth Differentiation Factor 15 Gene Expression by Curcumin in Patients with Beta-Thalassemia Intermedia
Published in Clinical laboratory (Heidelberg) (01-01-2024)“…β-thalassemia is an inherited disorder caused by defects in the synthesis of the beta-globin chain. One of the significant clinical complications in…”
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The effect of decitabine on the expression and methylation of the PPP1CA, BTG2, and PTEN in association with changes in miR‐125b, miR‐17, and miR‐181b in NALM6 cell line
Published in Journal of cellular biochemistry (01-08-2019)“…Precursor B‐cell acute lymphoblastic leukemia (B‐ALL) is the most prevalent pediatric cancer. DNA methylation and changes in the microRNAs (miRNAs) expression…”
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Up-regulated lncRNA-PVT1 expression in peripheral blood mononuclear cells of patients with coronary artery disease is correlated with decreased interleukin-10 production
Published in Molecular biology reports (01-05-2022)“…Objectives Plasmacytoma variant translocation 1 (PVT1) is a newly discovered long non-coding RNA, which has not been previously studied in the inflammatory…”
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Stevia rebaudiana extract attenuate metabolic disorders in diabetic rats via modulation of glucose transport and antioxidant signaling pathways and aquaporin‐2 expression in two extrahepatic tissues
Published in Journal of food biochemistry (01-08-2020)“…Today, plant‐based therapies have been attracted attention to overcome diabetes complications. This study was an attempt to evaluate whether antidiabetic and…”
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Abstract 294: Altered ARID1A expression in colorectal cancer
Published in Cancer research (Chicago, Ill.) (15-08-2020)“…Abstract Background: ARID1A has been described as a tumor suppressor gene, participating in chromatin re-modeling, epithelial-mesenchymal-transition and many…”
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An Expert Overview on Therapies in Non-Transfusion-Dependent Thalassemia: Classical to Cutting Edge in Treatment
Published in Hemoglobin (04-03-2023)“…The thalassemia issue is a growing worldwide health concern that anticipates the number of patients suffering from the disease will soon increase…”
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Expression and methylation status of BTG2 , PPP1CA , and PEG3 genes in colon adenocarcinoma cell lines: promising treatment targets
Published in Gastroenterology and hepatology from bed to bench (01-01-2022)“…This study investigated the association between methylation status and expression levels of , , and genes in colon cancer. Aberrant DNA methylation is one of…”
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The Role of endoplasmic reticulum metallo protease 1 on Autophagy Pathway in HCT-116 Colorectal Cancer Cell Line
Published in Iranian journal of colorectal research (01-06-2021)“…Background: Autophagy and unfolded protein response (UPR) are mechanisms with dual roles in both maintaining the cellular homeostasis and progression of…”
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