Search Results - "Erez, Baruch"
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Fecal microbiota transplant promotes response in immunotherapy-refractory melanoma patients
Published in Science (American Association for the Advancement of Science) (05-02-2021)“…The gut microbiome has been shown to influence the response of tumors to anti-PD-1 (programmed cell death-1) immunotherapy in preclinical mouse models and…”
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Immune-Related Adverse Events (irAEs): Diagnosis, Management, and Clinical Pearls
Published in Current oncology reports (21-03-2020)“…Purpose of Review While immune checkpoint inhibitor (ICI) therapy has improved melanoma patient outcomes, it has also resulted in the rise of unique…”
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Proteomics of Melanoma Response to Immunotherapy Reveals Mitochondrial Dependence
Published in Cell (19-09-2019)“…Immunotherapy has revolutionized cancer treatment, yet most patients do not respond. Here, we investigated mechanisms of response by profiling the proteome of…”
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Possible immune adverse events as predictors of durable response to BRAF inhibitors in patients with BRAF V600–mutant metastatic melanoma
Published in European journal of cancer (1990) (01-09-2018)“…BRAF inhibitors (BRAFi) and MEK inhibitors (MEKi) are among the cornerstones of metastatic melanoma therapy demonstrating excellent response rates with…”
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Point of injury tourniquet application during Operation Protective Edge-What do we learn?
Published in The journal of trauma and acute care surgery (01-08-2017)“…Hemorrhage is a leading cause of preventable death on the battlefield. Timely tourniquet application to massively bleeding extremity wounds is critical for…”
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TNFSF4 (OX40L) expression and survival in locally advanced and metastatic melanoma
Published in Cancer Immunology, Immunotherapy (01-09-2019)“…Immunotherapy with checkpoint inhibitors revolutionized melanoma treatment in both the adjuvant and metastatic setting, yet not all metastatic patients…”
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CXCR2 Expression in Tumor Cells is a Poor Prognostic Factor and Promotes Invasion and Metastasis in Lung Adenocarcinoma
Published in Cancer research (Chicago, Ill.) (15-01-2013)“…CXCR2 in non-small cell lung cancer (NSCLC) has been studied mainly in stromal cells and is known to increase tumor inflammation and angiogenesis. Here, we…”
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Elective neck dissection versus observation in patients with head and neck cutaneous squamous cell carcinoma
Published in Cancer (01-12-2021)“…Background The survival benefit of elective neck dissection (END) for patients with cutaneous squamous cell carcinoma (cSCC) of the head and neck and no…”
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Dietary fiber and probiotics influence the gut microbiome and melanoma immunotherapy response
Published in Science (American Association for the Advancement of Science) (24-12-2021)“…Gut bacteria modulate the response to immune checkpoint blockade (ICB) treatment in cancer, but the effect of diet and supplements on this interaction is not…”
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Inclusion of extranodal extension in the lymph node classification of cutaneous squamous cell carcinoma of the head and neck
Published in Cancer (15-04-2021)“…Background The prognostic performance of the recently updated American Joint Committee on Cancer lymph node classification of cutaneous head and neck squamous…”
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MYC Induces Immunotherapy and IFNγ Resistance Through Downregulation of JAK2
Published in Cancer immunology research (05-07-2023)“…Immunotherapy has revolutionized the treatment of advanced melanoma. Because the pathways mediating resistance to immunotherapy are largely unknown, we…”
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Does practice make perfect? Prospectively comparing effects of 2 amounts of practice on tourniquet use performance
Published in The American journal of emergency medicine (01-12-2016)“…Although a lifesaving skill, currently, there is no consensus for the required amount of practice in tourniquet use. We compared the effect of 2 amounts of…”
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Histopathological expression analysis of intercellular adhesion molecule 1 (ICAM-1) along development and progression of human melanoma
Published in Oncotarget (21-11-2017)“…Intercellular adhesion molecule 1 (ICAM-1) protein is an important adhesion molecule that facilitates metastasis on one hand, and on the other hand supports…”
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Combined MEK and VEGFR Inhibition in Orthotopic Human Lung Cancer Models Results in Enhanced Inhibition of Tumor Angiogenesis, Growth, and Metastasis
Published in Clinical cancer research (15-03-2012)“…Ras/Raf/mitogen-activated protein-extracellular signal-regulated kinase (ERK) kinase (MEK)/ERK signaling is critical for tumor cell proliferation and survival…”
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Abstract PO-074: The evolution of the tumor immune microenvironment in immunosuppressed patients with cutaneous squamous cell carcinoma
Published in Clinical cancer research (15-09-2023)“…Abstract Immunosuppression is a major risk and prognostic factor for cutaneous squamous cell carcinoma (cSCC). Immune checkpoint inhibition is approved for the…”
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Confidence-Competence Mismatch and Reasons for Failure of Non-Medical Tourniquet Users
Published in Prehospital emergency care (02-01-2017)“…Objective: Tourniquet application is a lifesaving skill taught worldwide in first aid bleeding control courses. We observed performance among non-medical users…”
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Immune-Related Adverse Events (irAEs): Diagnosis, Management, and Clinical Pearls
Published in Current oncology reports (01-04-2020)Get full text
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Extending a Helping Hand: A Comparison of Israel Defense Forces Medical Corps Humanitarian Aid Field Hospitals
Published in The Israel Medical Association journal (01-10-2016)“…During the past 6 years the Israel Defense Forces Medical Corps (IDF-MC) deployed three humanitarian delegation field hospitals (HDFHs) in disaster zones…”
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ADAR1-mediated regulation of melanoma invasion
Published in Nature communications (31-05-2018)“…Melanoma cells use different migratory strategies to exit the primary tumor mass and invade surrounding and subsequently distant tissues. We reported…”
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