Search Results - "Erdman Jr, John W."
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The Impact of LPS on Inflammatory Responses in Alpha-Tocopherol Deficient Mice
Published in Current developments in nutrition (01-08-2024)“…To facilitate the evaluation of vitamin E (α-tocopherol, αT) status on health outcomes, the αT transfer protein knockout (Ttpa–/–) mouse model has proved to be…”
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Successful dietary changes correlate with weight‐loss outcomes in a new dietary weight‐loss program
Published in Obesity science & practice (01-06-2024)“…Background Currently available behavioral and dietary weight‐loss programs lack magnitude and sustainability compared with bariatric surgery. A novel dietary…”
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3
Health and nutrition beyond essential nutrients: The evolution of the bioactives concept for human health
Published in Molecular aspects of medicine (01-02-2023)“…Our food supply contains a range of essential and non-essential food components. There are substantial epidemiologic findings and additional clinical data to…”
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Lycopene Accumulation in Transgenic Mice Lacking One or Both Carotenoid Cleaving Enzymes
Published in The Journal of nutrition (01-08-2023)“…β-carotene oxygenase 1 (BCO1) and β-carotene oxygenase 2 (BCO2) are responsible for the cleavage of carotenoids in mammals. The goals of this study were to (1)…”
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5
Complex interactions between dietary and genetic factors impact lycopene metabolism and distribution
Published in Archives of biochemistry and biophysics (15-11-2013)“…•There is wide tissue and plasma lycopene variability in response to dietary consumption.•Dietary factors include fat amount and type, food matrix, and…”
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Orchestration of miRNA Patterns by Testosterone and Dietary Tomato Carotenoids during Early Prostate Carcinogenesis in TRAMP Mice
Published in The Journal of nutrition (01-07-2023)“…The integrative effects of prostate cancer risk factors, such as diet and endocrine status, on cancer-associated miRNA expression are poorly defined. This…”
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α‐Tocopherol, but Not γ‐Tocopherol, Attenuates the Expression of Selective Tumor Necrosis Factor‐Alpha‐Induced Genes in Primary Human Aortic Cell Lines
Published in Lipids (01-05-2019)“…Of the antioxidant vitamin E isoforms, α‐tocopherol (αT) and γ‐tocopherol (γT) are the most abundant in the human diet, and αT is consumed from both natural…”
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Flavonoids and heart health: proceedings of the ILSI North America Flavonoids Workshop, May 31-June 1, 2005, Washington, DC
Published in The Journal of nutrition (01-03-2007)“…This article provides an overview of current research on flavonoids as presented during a workshop entitled, "Flavonoids and Heart Health," held by the ILSI…”
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Presence of Lunasin in Plasma of Men after Soy Protein Consumption
Published in Journal of agricultural and food chemistry (25-02-2009)“…Lunasin is a 43-amino acid bioactive peptide from soybean and other plant sources which is reported to possess anti-inflammatory and anticancer properties. The…”
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10
Optimization of Lycopene Extraction from Tomato Cell Suspension Culture by Response Surface Methodology
Published in Journal of agricultural and food chemistry (10-09-2008)“…Radioisotope-labeled lycopene is an important tool for biomedical research but currently is not commercially available. A tomato cell suspension culture system…”
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Combinations of tomato and broccoli enhance antitumor activity in dunning R3327-H prostate adenocarcinomas
Published in Cancer research (Chicago, Ill.) (15-01-2007)“…The consumption of diets containing 5 to 10 servings of fruits and vegetables daily is the foundation of public health recommendations for cancer prevention,…”
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Loss of carotene-9',10'-monooxygenase expression increases serum and tissue lycopene concentrations in lycopene-fed mice
Published in The Journal of nutrition (01-12-2010)“…Two enzymes have been identified for the oxidative metabolism of carotenoids in mammals. Carotene-15,15'-monooxygenase (CMO-I) primarily centrally cleaves…”
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13
Daily consumption of a dark chocolate containing flavanols and added sterol esters affects cardiovascular risk factors in a normotensive population with elevated cholesterol
Published in The Journal of nutrition (01-04-2008)“…Previous studies with plant sterols (PS) and cocoa flavanols (CF) provide support for their dietary use in maintaining cardiovascular health. This…”
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Apo-8'-lycopenal and apo-12'-lycopenal are metabolic products of lycopene in rat liver
Published in The Journal of nutrition (01-06-2006)“…The health benefits of lycopene as an anticarcinogenic compound have been widely studied but little is known about the metabolic products of lycopene produced…”
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Genetic ablation of carotene oxygenases and consumption of lycopene or tomato powder diets modulate carotenoid and lipid metabolism in mice
Published in Nutrition research (New York, N.Y.) (01-09-2013)“…Abstract Carotene-15,15′-monooxygenase (CMO-I) cleaves β -carotene to form vitamin A, whereas carotene-9′,10′-monooxygenase (CMO-II) preferentially cleaves…”
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Coconut Oil Enhances Tomato Carotenoid Tissue Accumulation Compared to Safflower Oil in the Mongolian Gerbil (Meriones unguiculatus)
Published in Journal of agricultural and food chemistry (29-08-2012)“…Evidence suggests that monounsaturated and polyunsaturated fats facilitate greater absorption of carotenoids than saturated fats. However, the comparison of…”
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17
Effects of Tomato and Soy Germ on Lipid Bioaccumulation and Atherosclerosis in ApoE−/− Mice
Published in Journal of food science (01-08-2015)“…Dietary patterns with cardiovascular benefits have been recommended, but the relative contributions of individual foods and food components, alone or in…”
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An interaction between carotene-15,15′-monooxygenase expression and consumption of a tomato or lycopene-containing diet impacts serum and testicular testosterone
Published in International journal of cancer (15-07-2012)“…Lycopene, the red pigment of tomatoes, is hypothesized to reduce prostate cancer risk, a disease strongly dependent upon testosterone. In this study, mice…”
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Serum testosterone is reduced following short-term phytofluene, lycopene, or tomato powder consumption in F344 rats
Published in The Journal of nutrition (01-11-2006)“…Elevated serum androgens are associated with increased prostate cancer risk. Tomato consumption is also associated with reduced prostate cancer incidence, and…”
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Lycopene biodistribution is altered in 15,15'-carotenoid monooxygenase knockout mice
Published in The Journal of nutrition (01-12-2008)“…15,15'-carotenoid monooxygenase (CMO I) is generally recognized as the central carotenoid cleavage enzyme responsible for converting provitamin A carotenoids…”
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