CT-guided pleural needle biopsy in the diagnosis of malignant mesothelioma

Our goal was to determine the sensitivity of CT-guided closed pleural needle biopsy (CPNB) for the histopathologic diagnosis of diffuse malignant pleural mesothelioma (DMPM). Thirty patients with DMPM were studied with CT-guided CPNB. Tumor specimens were classified according to their cell types. In...

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Bibliographic Details
Published in:	Journal of computer assisted tomography Vol. 19; no. 3; p. 370
Main Authors:	Metintaş, M, Ozdemir, N, Işiksoy, S, Kaya, T, Ekici, M, Erginel, S, Harmanci, E, Erdinç, P, Ulgey, N, Alataş, F
Format:	Journal Article
Language:	English
Published:	United States 01-05-1995
Subjects:	Adult Aged Biopsy, Needle - methods Female Humans Male Mesothelioma - diagnostic imaging Mesothelioma - pathology Middle Aged Pleural Neoplasms - diagnostic imaging Pleural Neoplasms - pathology Prospective Studies Tomography, X-Ray Computed - methods
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Summary:	Our goal was to determine the sensitivity of CT-guided closed pleural needle biopsy (CPNB) for the histopathologic diagnosis of diffuse malignant pleural mesothelioma (DMPM). Thirty patients with DMPM were studied with CT-guided CPNB. Tumor specimens were classified according to their cell types. In 25 (83.3%) patients, the diagnosis was made by CT-guided CPNB. The remaining five patients were diagnosed by thoracoscopy, thoracotomy, or excisional biopsy of the chest wall mass. Pneumothorax was observed in 9.5% of patients and local seeding of tumor in 21.7% of patients who underwent CPNB. Properly performed CPNB under CT guidance may yield an increased sensitivity for the diagnosis of diffuse malignant pleural mesothelioma.
ISSN:	0363-8715
DOI:	10.1097/00004728-199505000-00006