Search Results - "Erdel, M."

Regulation of transcription factor E2F3a and its clinical relevance in ovarian cancer by Reimer, D, Hubalek, M, Kiefel, H, Riedle, S, Skvortsov, S, Erdel, M, Hofstetter, G, Concin, N, Fiegl, H, Müller-Holzner, E, Marth, C, Altevogt, P, Zeimet, A G

“…Recently we showed an integral epidermal growth factor receptor (EGFR)–E2F3a signaling path, in which E2F3a was found to be essential in EGFR-mediated…”
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Clinical outcome of pretreated B-cell chronic lymphocytic leukemia following alemtuzumab therapy: a retrospective study on various cytogenetic risk categories by Fiegl, M., Erdel, M., Tinhofer, I., Brychtova, Y., Panovska, A., Doubek, M., Eigenberger, K., Fonatsch, C., Hopfinger, G., Mühlberger, H., Zabernigg, A., Falkner, F., Gastl, G., Mayer, J., Greil, R.

“…Patients with B-cell chronic lymphocytic leukemia (CLL) with 17p deletion respond poorly to chemotherapy. This retrospective study evaluated the benefit of…”
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Two novel translocation breakpoints upstream of SOX9 define borders of the proximal and distal breakpoint cluster region in campomelic dysplasia by Leipoldt, M, Erdel, M, Bien-Willner, GA, Smyk, M, Theurl, M, Yatsenko, SA, Lupski, JR, Lane, AH, Shanske, AL, Stankiewicz, P, Scherer, G

“…The semilethal skeletal malformation syndrome campomelic dysplasia (CD) with or without XY sex reversal is caused by mutations within the SOX9 gene on 17q24.3…”
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Switch from antagonist to agonist of the androgen receptor blocker bicalutamide is associated with prostate tumour progression in a new model system by CULIG, Z, HOFFMANN, J, KLOCKER, H, ERDEL, M, EDER, I. E, HOBISCH, A, HITTMAIR, A, BARTSCH, G, UTERMANN, G, SCHNEIDER, M. R, PARCZYK, K

“…Advanced prostate cancer is treated by androgen ablation and/or androgen receptor (AR) antagonists. In order to investigate the mechanisms relevant to the…”
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Whole genome amplification from microdissected chromosomes by Höckner, M, Erdel, M, Spreiz, A, Utermann, G, Kotzot, D

“…Over the last years various whole genome amplification (WGA) methods have been established for genetic investigations from a limited number of cells or small…”
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Switch of the mutation type of the NPM1 gene in acute myeloid leukemia (AML): relapse or secondary AML? by Webersinke, G, Kranewitter, W, Deutschbauer, S, Zach, O, Hasenschwandtner, S, Wiesinger, K, Erdel, M, Marschon, R, Böhm, A, Tschurtschenthaler, G

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IgM myeloma: more on a rare entity by Willenbacher, E., Erdel, M., Strasser, U., Gastl, G., Schmidt, S., Gunsilius, E., Willenbacher, W.

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Parental origin of de novo cytogenetically balanced reciprocal non-Robertsonian translocations by Höckner, M, Spreiz, A, Frühmesser, A, Tzschach, A, Dufke, A, Rittinger, O, Kalscheuer, V, Singer, S, Erdel, M, Fauth, C, Grossmann, V, Utermann, G, Zschocke, J, Kotzot, D

“…De novo cytogenetically balanced reciprocal non-Robertsonian translocations are rare findings in clinical cytogenetics and might be associated with an abnormal…”
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Parental origin of apparently balanced de novo complex chromosomal rearrangements investigated by microdissection, whole genome amplification, and microsatellite-mediated haplotype analysis by Grossmann, V, Höckner, M, Karmous-Benailly, H, Liang, D, Puttinger, R, Quadrelli, R, Röthlisberger, B, Huber, A, Wu, L, Spreiz, A, Fauth, C, Erdel, M, Zschocke, J, Utermann, G, Kotzot, D

“…Grossmann V, Höckner M, Karmous‐Benailly H, Liang D, Puttinger R, Quadrelli R, Röthlisberger B, Huber A, Wu L, Spreiz A, Fauth C, Erdel M, Zschocke J, Utermann…”
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LIM-domain protein cysteine- and glycine-rich protein 2 (CRP2) is a novel marker of hepatic stellate cells and binding partner of the protein inhibitor of activated STAT1 by Weiskirchen, R, Moser, M, Weiskirchen, S, Erdel, M, Dahmen, S, Buettner, R, Gressner, A M

“…Activation of hepatic stellate cells is considered to be the main step in the development of liver fibrosis, which is characterized by the transition of…”
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Unfavourable prognosis of patients with trisomy 18q21 detected by fluorescence in situ hybridisation in t(11;18) negative, surgically resected, gastrointestinal B cell lymphomas by Krugmann, J, Tzankov, A, Dirnhofer, S, Fend, F, Greil, R, Siebert, R, Erdel, M

“…Background: The most frequent cytogenetic alteration in gastrointestinal (GI) B cell lymphoma (BCL) is t(11;18)(q21;q21). GI B cell non-Hodgkin lymphomas…”
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Three novel SRY mutations in XY gonadal dysgenesis and the enigma of XY gonadal dysgenesis cases without SRY mutations by Scherer, G, Held, M, Erdel, M, Meschede, D, Horst, J, Lesniewicz, R, Midro, A T

“…Mutations in the Y-located testis-determining gene SRY are one cause for XY sex reversal. We have previously identified four SRY mutations in a total of 45…”
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Counting the repetitive kringle-IV repeats in the gene encoding human apolipoprotein(a) by fibre-FISH by Utermann, Gerd, Erdel, Martin, Hubalek, Michael, Lingenhel, Arno, Kofler, Kurt, Duba, Hans-C

“…Fluorescence in situ hybridization (FISH) using completely extended chromatin fibres from interphase nuclei was pioneered by Wiegant et al.. Since then,…”
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High-resolution mapping of the human 4q21 and the mouse 5E3 SCYB chemokine cluster by fiber-fluorescence in situ hybridization by Erdel, M, Theurl, M, Meyer, M, Duba, H C, Utermann, G, Werner-Felmayer, G

“…The CXC chemokine or small inducible cytokine B (SCYB) subfamily includes the T-cell chemoattractants MIG (CXCL9, SCYB9), IP-10 (CXCL10, SCYB10), and I-TAC…”
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Combined study of prostatic carcinoma by classical cytogenetic analysis and comparative genomic hybridization by Verdorfer, I, Hobisch, A, Culig, Z, Hittmair, A, Bartsch, G, Erdel, M, Duba, H C, Utermann, G

“…Conventional cytogenetic analysis of prostatic carcinoma (PC) is characterized by inefficient growth of tumor cells during in vitro culture, leading to a lack…”
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Cloning, genomic sequence, and chromosome mapping of Scyb11, the murine homologue of SCYB11 (alias betaR1/H174/SCYB9B/I-TAC/IP-9/CXCL11) by Meyer, M, Erdel, M, Duba, H C, Werner, E R, Werner-Felmayer, G

“…A T-cell attracting CXC chemokine phylogenetically related to MIG and SCYB10 was recently characterized and termed SCYB11 (alias…”
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Hypermetaphase and interphase fluorescence in situ hybridisation for monitoring of remission status in Philadelphia chromosome positive chronic myeloid leukaemia by Duba, H C, Hilbe, W, Mehringer, A, Erdel, M, Thaler, J, Utermann, G

“…Interferon (IFN) alone or in combination with cytostatic drugs, can induce major and durable cytogenetic remissions in chronic myelogenous leukaemia (CML)…”
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Comparative genomic hybridization reveals a partial de novo trisomy 6q23-qter in an infant with congenital malformations : delineation of the phenotype by ERDEL, M, DUBA, H.-C, VERDORFER, I, LINGENHEL, A, GEIGER, R, GUTENBERGER, K.-H, LUDESCHER, E, UTERMANN, B, UTERMANN, G

“…We report the use of comparative genomic hybridization (CGH) to define the origin of a small extra segment (unidentifiable by classical cytogenetics) present…”
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The human gene encoding SCYB9B, a putative novel CXC chemokine, maps to human chromosome 4q21 like the closely related genes for MIG (SCYB9) and INP10 (SCYB10) by Erdel, M, Laich, A, Utermann, G, Werner, E R, Werner-Felmayer, G

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Localization of cathepsin B in two human lung cancer cell lines by Erdel, M, Trefz, G, Spiess, E, Habermaas, S, Spring, H, Lah, T, Ebert, W

“…We demonstrated the cysteine proteinase cathepsin B in two human lung tumor cell lines by cytochemical and immunocytochemical methods. The cell lines were…”
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