Search Results - "Ercu, Maria"
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Roles of A-Kinase Anchoring Proteins and Phosphodiesterases in the Cardiovascular System
Published in Journal of cardiovascular development and disease (20-02-2018)“…A-kinase anchoring proteins (AKAPs) and cyclic nucleotide phosphodiesterases (PDEs) are essential enzymes in the cyclic adenosine 3'-5' monophosphate (cAMP)…”
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Abstract 12025: Phosphodiesterase 3A Mutations Limit Hypertension-Induced Cardiac Damage
Published in Circulation (New York, N.Y.) (16-11-2021)“…Hypertension affects more than 1 billion people worldwide and can cause cardiac hypertrophy and ultimately heart failure, a condition with an unmet medical…”
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Mutations in Phosphodiesterase 3A ( PDE3A ) Cause Hypertension Without Cardiac Damage
Published in Hypertension (Dallas, Tex. 1979) (01-06-2023)“…Hypertension with brachydactyly (HTNB) represents an autosomal dominant form of hypertension. It is a rare syndrome, in which the blood pressure can rise by…”
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Mutations in phosphodiesterase 3A (PDE3A) Cause Hypertension Without Cardiac Damage
Published in Hypertension (Dallas, Tex. 1979) (10-04-2023)“…Hypertension with brachydactyly (HTNB) represents an autosomal dominant form of hypertension. It is a rare syndrome, in which the blood pressure can rise by…”
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Integrated Proteomics Unveils Nuclear PDE3A2 as a Regulator of Cardiac Myocyte Hypertrophy
Published in Circulation research (31-03-2023)“…Signaling by cAMP is organized in multiple distinct subcellular nanodomains regulated by cAMP-hydrolyzing PDEs (phosphodiesterases). Cardiac β-adrenergic…”
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Phosphodiesterase 3A and Arterial Hypertension
Published in Circulation (New York, N.Y.) (14-07-2020)“…Background: High blood pressure is the primary risk factor for cardiovascular death worldwide. Autosomal dominant hypertension with brachydactyly clinically…”
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Mutant Phosphodiesterase 3A Protects From Hypertension-Induced Cardiac Damage
Published in Circulation (New York, N.Y.) (06-12-2022)“…Phosphodiesterase 3A ( ) gain-of-function mutations cause hypertension with brachydactyly (HTNB) and lead to stroke. Increased peripheral vascular resistance,…”
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Phosphodiesterase 3A activation for cardioprotection
Published in Journal of molecular and cellular cardiology (31-12-2022)Get full text
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Abstract 039: The PDE3A Gene Regulates Blood Pressure
Published in Hypertension (Dallas, Tex. 1979) (01-09-2019)“…Abstract only Hypertension is the greatest driver of cardiovascular disease, the most common cause of death. Finding novel model mechanisms for blood-pressure…”
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MYCN and HDAC5 transcriptionally repress CD9 to trigger invasion and metastasis in neuroblastoma
Published in Oncotarget (11-10-2016)“…The systemic and resistant nature of metastatic neuroblastoma renders it largely incurable with current multimodal treatment. Clinical progression stems mainly…”
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Phosphodiesterase 3A and Arterial Hypertension
Published in Circulation (New York, N.Y.) (14-07-2020)Get full text
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