Search Results - "Erben, G."

Vitamin D and Cardiovascular Disease, with Emphasis on Hypertension, Atherosclerosis, and Heart Failure by Latic, Nejla, Erben, Reinhold G

“…Vitamin D deficiency is the most common nutritional deficiency, affecting almost one billion people worldwide. Vitamin D is mostly known for its role in…”
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Physiological Actions of Fibroblast Growth Factor-23 by Erben, Reinhold G

“…Fibroblast growth factor-23 (FGF23) is a bone-derived hormone suppressing phosphate reabsorption and vitamin D hormone synthesis in the kidney. At…”
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Pleiotropic Actions of FGF23 by Erben, Reinhold G.

“…Fibroblast growth factor-23 (FGF23) is a bone-derived hormone, mainly produced by osteoblasts and osteocytes in response to increased extracellular phosphate…”
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Interaction of Vitamin D with Peptide Hormones with Emphasis on Parathyroid Hormone, FGF23, and the Renin-Angiotensin-Aldosterone System by Latic, Nejla, Erben, Reinhold G

“…The seminal discoveries that parathyroid hormone (PTH) and fibroblast growth factor 23 (FGF23) are major endocrine regulators of vitamin D metabolism led to a…”
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Excessive Osteocytic Fgf23 Secretion Contributes to Pyrophosphate Accumulation and Mineralization Defect in Hyp Mice by Murali, Sathish K, Andrukhova, Olena, Clinkenbeard, Erica L, White, Kenneth E, Erben, Reinhold G

“…X-linked hypophosphatemia (XLH) is the most frequent form of inherited rickets in humans caused by mutations in the phosphate-regulating gene with homologies…”
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The kidney is the principal organ mediating klotho effects by Lindberg, Karolina, Amin, Risul, Moe, Orson W, Hu, Ming-Chang, Erben, Reinhold G, Östman Wernerson, Annika, Lanske, Beate, Olauson, Hannes, Larsson, Tobias E

“…Klotho was discovered as an antiaging gene, and α-Klotho (Klotho) is expressed in multiple tissues with a broad set of biologic functions. Membrane-bound…”
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FGF23 Regulates Bone Mineralization in a 1,25(OH)2D3 and Klotho‐Independent Manner by Murali, Sathish Kumar, Roschger, Paul, Zeitz, Ute, Klaushofer, Klaus, Andrukhova, Olena, Erben, Reinhold G

“…ABSTRACT Fibroblast growth factor‐23 (Fgf23) is a bone‐derived hormone, suppressing phosphate reabsorption and vitamin D hormone (1,25(OH)2D3) production in…”
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Estrogen Regulates Bone Turnover by Targeting RANKL Expression in Bone Lining Cells by Streicher, Carmen, Heyny, Alexandra, Andrukhova, Olena, Haigl, Barbara, Slavic, Svetlana, Schüler, Christiane, Kollmann, Karoline, Kantner, Ingrid, Sexl, Veronika, Kleiter, Miriam, Hofbauer, Lorenz C., Kostenuik, Paul J., Erben, Reinhold G.

“…Estrogen is critical for skeletal homeostasis and regulates bone remodeling, in part, by modulating the expression of receptor activator of NF-κB ligand…”
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FGF23 regulates renal sodium handling and blood pressure by Andrukhova, Olena, Slavic, Svetlana, Smorodchenko, Alina, Zeitz, Ute, Shalhoub, Victoria, Lanske, Beate, Pohl, Elena E, Erben, Reinhold G

“…Fibroblast growth factor‐23 (FGF23) is a bone‐derived hormone regulating renal phosphate reabsorption and vitamin D synthesis in renal proximal tubules. Here,…”
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Vitamin D Is a Regulator of Endothelial Nitric Oxide Synthase and Arterial Stiffness in Mice by Andrukhova, Olena, Slavic, Svetlana, Zeitz, Ute, Riesen, Sabine C, Heppelmann, Monika S, Ambrisko, Tamas D, Markovic, Mato, Kuebler, Wolfgang M, Erben, Reinhold G

“…The vitamin D hormone 1α,25-dihydroxyvitamin D3 [1,25(OH)2D3] is essential for the preservation of serum calcium and phosphate levels but may also be important…”
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FGF23 acts directly on renal proximal tubules to induce phosphaturia through activation of the ERK1/2–SGK1 signaling pathway by Andrukhova, Olena, Zeitz, Ute, Goetz, Regina, Mohammadi, Moosa, Lanske, Beate, Erben, Reinhold G

“…Abstract Fibroblast growth factor-23 (FGF23) is a bone-derived endocrine regulator of phosphate homeostasis which inhibits renal tubular phosphate…”
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Randomized Trial of Etelcalcetide for Cardiac Hypertrophy in Hemodialysis by Dörr, Katharina, Kammer, Michael, Reindl-Schwaighofer, Roman, Lorenz, Matthias, Prikoszovich, Thomas, Marculescu, Rodrig, Beitzke, Dietrich, Wielandner, Alice, Erben, Reinhold G., Oberbauer, Rainer

“…[Figure: see text]…”
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Experimental Myocardial Infarction Upregulates Circulating Fibroblast Growth Factor‐23 by Andrukhova, Olena, Slavic, Svetlana, Odörfer, Kathrin I, Erben, Reinhold G

“…ABSTRACT Myocardial infarction (MI) is a major cause of death worldwide. Epidemiological studies have linked vitamin D deficiency to MI incidence. Because…”
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FGF23 and Vitamin D Metabolism by Latic, Nejla, Erben, Reinhold G.

“…ABSTRACT Apart from its phosphaturic action, the bone‐derived hormone fibroblast growth factor‐23 (FGF23) is also an essential regulator of vitamin D…”
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Local MicroRNA Modulation Using a Novel Anti-miR-21–Eluting Stent Effectively Prevents Experimental In-Stent Restenosis by Wang, Dong, Deuse, Tobias, Stubbendorff, Mandy, Chernogubova, Ekaterina, Erben, Reinhold G, Eken, Suzanne M, Jin, Hong, Li, Yuhuang, Busch, Albert, Heeger, Christian-H, Behnisch, Boris, Reichenspurner, Hermann, Robbins, Robert C, Spin, Joshua M, Tsao, Philip S, Schrepfer, Sonja, Maegdefessel, Lars

“…OBJECTIVE—Despite advances in stent technology for vascular interventions, in-stent restenosis (ISR) because of myointimal hyperplasia remains a major…”
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Genetic evidence of serum phosphate-independent functions of FGF-23 on bone by Sitara, Despina, Kim, Somi, Razzaque, Mohammed S, Bergwitz, Clemens, Taguchi, Takashi, Schüler, Christiane, Erben, Reinhold G, Lanske, Beate

“…Maintenance of physiologic phosphate balance is of crucial biological importance, as it is fundamental to cellular function, energy metabolism, and skeletal…”
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The bone is the major source of high circulating intact fibroblast growth factor-23 in acute murine polymicrobial sepsis induced by cecum ligation puncture by Bayer, Jessica, Vaghela, Ravikumar, Drechsler, Susanne, Osuchowski, Marcin F, Erben, Reinhold G, Andrukhova, Olena

“…Fibroblast growth factor-23 (FGF23), a bone-produced hormone, plays a critical role in mineral homeostasis. Human diseases associated with excessive intact…”
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Fgf23 and parathyroid hormone signaling interact in kidney and bone by Andrukhova, Olena, Streicher, Carmen, Zeitz, Ute, Erben, Reinhold G.

“…Fibroblast growth factor-23 (FGF23) is a bone-derived hormone, suppressing renal phosphate reabsorption and vitamin D hormone synthesis in proximal tubules,…”
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FGF23 regulation of renal tubular solute transport by Erben, Reinhold G, Andrukhova, Olena

“…PURPOSE OF REVIEWFibroblast growth factor-23 (FGF23) is a bone-derived hormone known to suppress phosphate reabsorption in the kidney. The purpose of this…”
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Increased Osteopontin Contributes to Inhibition of Bone Mineralization in FGF23‐Deficient Mice by Yuan, Quan, Jiang, Yan, Zhao, Xuefeng, Sato, Tadatoshi, Densmore, Michael, Schüler, Christiane, Erben, Reinhold G, McKee, Marc D, Lanske, Beate

“…ABSTRACT Excessive FGF23 has been identified as a pivotal phosphaturic factor leading to renal phosphate‐wasting and the subsequent development of rickets and…”
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