Search Results - "Erbani, Johanna"

Endothelial E-selectin inhibition improves acute myeloid leukaemia therapy by disrupting vascular niche-mediated chemoresistance by Barbier, Valerie, Erbani, Johanna, Fiveash, Corrine, Davies, Julie M., Tay, Joshua, Tallack, Michael R., Lowe, Jessica, Magnani, John L., Pattabiraman, Diwakar R., Perkins, Andrew C., Lisle, Jessica, Rasko, John E. J., Levesque, Jean-Pierre, Winkler, Ingrid G.

“…The endothelial cell adhesion molecule E-selectin is a key component of the bone marrow hematopoietic stem cell (HSC) vascular niche regulating balance between…”
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Protocol for studying macrophage lipid crosstalk with murine tumor cells by Kloosterman, Daan J., Farber, Martina, Boon, Menno, Erbani, Johanna, Akkari, Leila

“…Lipid accumulation has recently emerged as a key feature underlying the pro-tumorigenic role of macrophages. Here, we present a workflow to study macrophage…”
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Acute Myeloid Leukemia Chemo-Resistance Is Mediated by E-selectin Receptor CD162 in Bone Marrow Niches by Erbani, Johanna, Tay, Joshua, Barbier, Valerie, Levesque, Jean-Pierre, Winkler, Ingrid G.

“…The interactions of leukemia cells with the bone marrow (BM) microenvironment is critical for disease progression and resistance to treatment. We have recently…”
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Therapy-induced shaping of the glioblastoma microenvironment: Macrophages at play by Erbani, Johanna, Boon, Menno, Akkari, Leila

“…The intricate cross-talks between tumor cells and their microenvironment play a key role in cancer progression and resistance to treatment. In recent years,…”
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CD162 Is a Key E-Selectin Receptor Promoting Acute Myeloid Leukemia Chemo-Resistance in the Bone Marrow Niche by Erbani, Johanna D, Tay, Joshua, Barbier, Valerie, Levesque, Jean-Pierre, Magnani, John L., Winkler, Ingrid G

“…We have recently found that the vascular adhesion molecule E(endothelial)-selectin is a critical bone marrow niche component mediating acute myeloid leukemia…”
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Pluripotent Stem Cells and Other Innovative Strategies for the Treatment of Ocular Surface Diseases by Erbani, Johanna, Aberdam, Daniel, Larghero, Jerome, Vanneaux, Valérie

“…The cornea provides two thirds of the refractive power of the eye and protection against insults such as infection and injury. The outermost tissue of the…”
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Blocking Vascular Niche E-Selectin Dampens AML Stem Cell Regeneration/Survival Potential In Vivo By Inhibiting MAPK/ERK and PI3K/AKT Signalling Pathways by Winkler, Ingrid G, Barbier, Valerie, Tay, Joshua, Levesque, Jean-Pierre, Magnani, John L., Fiveash, Corrine E, Erbani, Johanna D

“…We have previously shown vascular E (endothelial)-selectin to play a key role in niche-mediated chemo-resistance in Acute Myeloid Leukaemia (AML). Now we…”
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CD44 AND CD162 ARE KEY E-SELECTIN RECEPTORS PROMOTING ACUTE MYELOID LEUKEMIA CHEMORESISTANCE WITHIN THE BONE MARROW NICHE by Erbani, Johanna, Barbier, Valerie, Tay, Joshua, Lowe, Jessica, Levesque, Jean-Pierre, Winkler, Ingrid

“…The unique interactions of leukemia cells with the bone marrow (BM) microenvironment (niche) are critical for disease progression and resistance to treatment…”
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Macrophage-mediated myelin recycling fuels brain cancer malignancy by Kloosterman, Daan J, Erbani, Johanna, Boon, Menno, Farber, Martina, Handgraaf, Shanna M, Ando-Kuri, Masami, Sánchez-López, Elena, Fontein, Bauke, Mertz, Marjolijn, Nieuwland, Marja, Liu, Ning Qing, Forn-Cuni, Gabriel, van der Wel, Nicole N, Grootemaat, Anita E, Reinalda, Luuk, van Kasteren, Sander I, de Wit, Elzo, Ruffell, Brian, Snaar-Jagalska, Ewa, Petrecca, Kevin, Brandsma, Dieta, Kros, Alexander, Giera, Martin, Akkari, Leila

“…Tumors growing in metabolically challenged environments, such as glioblastoma in the brain, are particularly reliant on crosstalk with their tumor…”
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3033 - Vascular Niche E-Selectin Promotes Acute Myeloid Leukemia Resistance to Chemotherapy via Its Receptors CD44 and CD162 by Erbani, Johanna, Barbier, Valerie, Lowe, Jessica, Tay, Joshua, Levesque, Jean-Pierre, Winkler, Ingrid

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Vascular Niche E-Selectin Promotes Acute Myeloid Leukemia Resistance to Chemotherapy via Its Receptors CD44 and CD162 by Erbani, Johanna, Barbier, Valerie, Lowe, Jessica, Tay, Joshua, Levesque, Jean-Pierre, Winkler, Ingrid

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Vascular E-Selectin Acts As a Gatekeeper Inducing Commitment and Loss of Self-Renewal in HSC Transmigrating through the Marrow Vasculature by Winkler, Ingrid G, Barbier, Valerie, Lowe, Jessica, Tay, Joshua, Magnani, John L, Marlton, Paula, Mills, Anthony K, Perkins, Andrew, Fiveash, Corrine E, Erbani, Johanna M, Levesque, Jean-Pierre

“…Hematopoietic stem cells (HSC) reside in specific peri-vascular niches in the bone marrow (BM). We have shown interactions with the inflammatory vascular…”
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Vascular E-Selectin Mediates Chemo-Resistance in Acute Myeloid Leukemia Initiating Cells Via Canonical Receptors PSGL-1 (CD162) and Hcell (CD44) and AKT Signaling by Winkler, Ingrid G, Erbani, Johanna M, Barbier, Valerie, Davies, Julie M, Tay, Joshua, Fiveash, Corrine E, Lowe, Jessica, Tallack, Michael, Magnani, John L, Levesque, Jean-Pierre

“…The vascular adhesion molecule E-selectin is a key component of the bone marrow (BM) vascular niche, awakening otherwise dormant hematopoietic stem cells (HSC)…”
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Vascular E-Selectin Protects Leukemia Cells from Chemotherapy By Directly Activating Pro-Survival NF-Kb Signalling - Therapeutic Blockade of E-Selectin Dampens NF-Kb Activation by Winkler, Ingrid G, Barbier, Valerie, Ward, Micheal, Tallack, Michael, Lowe, Jessica, Davies, Julie, Erbani, Johanna, Magnani, John L, Levesque, Jean-Pierre

“…The vascular adhesion molecule E-selectin is a key component of the Bone Marrow (BM) Haematopoietic Stem Cell (HSC) niche prompting HSC to proliferate at the…”
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