Search Results - "Erausquin, Elena"
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Structural plasticity in I-Ag7 links autoreactivity to hybrid insulin peptides in type I diabetes
Published in Frontiers in immunology (28-07-2022)“…We recently provided evidence for promiscuous recognition of several different hybrid insulin peptides (HIPs) by the highly diabetogenic, I-A g7 -restricted…”
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2
Structural vulnerability in EPCR suggests functional modulation
Published in Scientific reports (31-01-2024)“…The endothelial protein C receptor (EPCR) is a fundamental component of the vascular system in mammals due to its contribution in maintaining blood in a…”
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Tubastatin A, an inhibitor of HDAC6, enhances temozolomide‑induced apoptosis and reverses the malignant phenotype of glioblastoma cells
Published in International journal of oncology (01-05-2019)“…Glioblastoma or grade IV astrocytoma is the most common and lethal form of glioma. Current glioblastoma treatment strategies use surgery followed by…”
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4
Identification of a broad lipid repertoire associated to the endothelial cell protein C receptor (EPCR)
Published in Scientific reports (06-09-2022)“…Evidence is mounting that the nature of the lipid bound to the endothelial cell protein C receptor (EPCR) has an impact on its biological roles, as observed in…”
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Silencing of Histone Deacetylase 6 Decreases Cellular Malignancy and Contributes to Primary Cilium Restoration, Epithelial-to-Mesenchymal Transition Reversion, and Autophagy Inhibition in Glioblastoma Cell Lines
Published in Biology (Basel, Switzerland) (26-05-2021)“…Glioblastoma multiforme, the most common type of malignant brain tumor as well as the most aggressive one, lacks an effective therapy. Glioblastoma presents…”
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Fine-tuned plasticity in a pMHC-II complex drives autorecognition by a highly diabetogenic T cell receptor
Published in Acta crystallographica. Section A, Foundations and advances (22-08-2023)“…Abstract only…”
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Structural plasticity in I-Ag7 links autoreactivity to hybrid insulin peptides in type I diabetes
Published in Acta crystallographica. Section A, Foundations and advances (22-08-2023)“…Abstract only…”
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Structural bases for the higher adherence to ACE2 conferred by the SARS‐CoV‐2 spike Q498Y substitution
Published in Acta crystallographica. Section D, Biological crystallography. (01-09-2022)“…A remarkable number of SARS‐CoV‐2 variants and other as yet unmonitored lineages harbor amino‐acid substitutions with the potential to modulate the interface…”
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