Search Results - "Eran Elinav"
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Interaction between microbiota and immunity in health and disease
Published in Cell research (01-06-2020)“…The interplay between the commensal microbiota and the mammalian immune system development and function includes multifold interactions in homeostasis and…”
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The pros, cons, and many unknowns of probiotics
Published in Nature medicine (01-05-2019)“…Consumption of over-the-counter probiotics for promotion of health and well-being has increased worldwide in recent years. However, although probiotic use has…”
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Inflammasome activation and regulation: toward a better understanding of complex mechanisms
Published in Cell discovery (09-06-2020)“…Inflammasomes are cytoplasmic multiprotein complexes comprising a sensor protein, inflammatory caspases, and in some but not all cases an adapter protein…”
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You are what you eat: diet, health and the gut microbiota
Published in Nature reviews. Gastroenterology & hepatology (01-01-2019)“…Since the renaissance of microbiome research in the past decade, much insight has accumulated in comprehending forces shaping the architecture and…”
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Bile acids in glucose metabolism in health and disease
Published in The Journal of experimental medicine (05-02-2018)“…Bile acids (BAs) are cholesterol-derived metabolites that facilitate the intestinal absorption and transport of dietary lipids. Recently, BAs also emerged as…”
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Diet–microbiota interactions and personalized nutrition
Published in Nature reviews. Microbiology (01-12-2019)“…Conceptual scientific and medical advances have led to a recent realization that there may be no single, one-size-fits-all diet and that differential human…”
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Microbiome-Modulated Metabolites at the Interface of Host Immunity
Published in The Journal of immunology (1950) (15-01-2017)“…The mammalian gastrointestinal tract and associated mucosal immune system harbor a large repertoire of metabolites of prokaryotic and eukaryotic origin that…”
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No guts, no research glory
Published in Nature medicine (01-02-2019)“…Eran Elinav is an immunologist at the Weizmann Institute of Science in Rehovot, Israel. He has earned many distinctions, including being named a Howard Hughes…”
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The cancer microbiome
Published in Nature reviews. Cancer (01-07-2019)“…Collectively known as the microbiota, the commensal bacteria and other microorganisms that colonize the epithelial surfaces of our body have been shown to…”
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The Role of the Immune System in Metabolic Health and Disease
Published in Cell metabolism (07-03-2017)“…In addition to the immune system’s traditional roles of conferring anti-infectious and anti-neoplastic protection, it has been recently implicated in the…”
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The intestinal microbiota fuelling metabolic inflammation
Published in Nature reviews. Immunology (01-01-2020)“…Low-grade inflammation is the hallmark of metabolic disorders such as obesity, type 2 diabetes and nonalcoholic fatty liver disease. Emerging evidence…”
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Human microbiome research: Growing pains and future promises
Published in PLoS biology (17-03-2023)“…Human microbiome research is evolving from describing associations to understanding the impact of bioactive strains on humans. Despite challenges, progress is…”
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Metabolites: messengers between the microbiota and the immune system
Published in Genes & development (15-07-2016)“…The mammalian intestine harbors one of the largest microbial densities on Earth, necessitating the implementation of control mechanisms by which the host…”
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Phages and their potential to modulate the microbiome and immunity
Published in Cellular & molecular immunology (01-04-2021)“…Bacteriophages (hence termed phages) are viruses that target bacteria and have long been considered as potential future treatments against antibiotic-resistant…”
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Immune-Microbiota Interplay and Colonization Resistance in Infection
Published in Molecular cell (21-05-2020)“…Commensal microbial communities inhabit biological niches in the mammalian host, where they impact the host’s physiology through induction of “colonization…”
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The role of the microbiome in NAFLD and NASH
Published in EMBO molecular medicine (01-02-2019)“…Nonalcoholic fatty liver disease (NAFLD) is the hepatic manifestation of cardiometabolic syndrome, which often also includes obesity, diabetes, and…”
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Nonnutritive sweeteners and glucose intolerance: Where do we go from here?
Published in The Journal of clinical investigation (15-05-2023)Get full text
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Hyperglycemia drives intestinal barrier dysfunction and risk for enteric infection
Published in Science (American Association for the Advancement of Science) (23-03-2018)“…Obesity, diabetes, and related manifestations are associated with an enhanced, but poorly understood, risk for mucosal infection and systemic inflammation…”
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Use of Metatranscriptomics in Microbiome Research
Published in Bioinformatics and Biology Insights (01-01-2016)“…The human intestinal microbiome is a microbial ecosystem that expresses as many as 100 times more genes than the human host, thereby constituting an important…”
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Nutrition Regulates Innate Immunity in Health and Disease
Published in Annual review of nutrition (23-09-2020)“…Nutrient content and nutrient timing are considered key regulators of human health and a variety of diseases and involve complex interactions with the mucosal…”
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