Search Results - "Epstein, Joshua"

Modelling to contain pandemics by Epstein, Joshua M

“…Agent-based computational models can capture irrational behaviour, complex social networks and global scale — all essential in confronting H1N1, says Joshua M…”
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Triple contagion: a two-fears epidemic model by Epstein, Joshua M, Hatna, Erez, Crodelle, Jennifer

“…We present a differential equations model in which contagious disease transmission is affected by contagious fear of the disease and contagious fear of the…”
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Why Model? by Epstein, Joshua M

“…This lecture treats some enduring misconceptions about modeling. One of these is that the goal is always prediction. The lecture distinguishes between…”
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Inverse Generative Social Science: Backward to the Future by Epstein, Joshua M

“…The agent-based model is the principal scientific instrument of generative social science. Typically, we design completed agents-fully endowed with rules and…”
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Coupled contagion dynamics of fear and disease: mathematical and computational explorations by Epstein, Joshua M, Parker, Jon, Cummings, Derek, Hammond, Ross A

“…In classical mathematical epidemiology, individuals do not adapt their contact behavior during epidemics. They do not endogenously engage, for example, in…”
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Patterns of Wetland Hydrologic Connectivity Across Coastal‐Plain Wetlandscapes by Lee, Esther, Epstein, Joshua M., Cohen, Matthew J.

“…Depressional wetlands influence the functions of wetlandscapes by storing and releasing water, providing critical habitat, amplifying carbon and nutrient…”
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Bortezomib with lenalidomide and dexamethasone versus lenalidomide and dexamethasone alone in patients with newly diagnosed myeloma without intent for immediate autologous stem-cell transplant (SWOG S0777): a randomised, open-label, phase 3 trial by Durie, Brian G M, Dr Prof, Hoering, Antje, PhD, Abidi, Muneer H, MD, Rajkumar, S Vincent, Prof, Epstein, Joshua, Prof, Kahanic, Stephen P, MD, Thakuri, Mohan, MD, Reu, Frederic, MD, Reynolds, Christopher M, MD, Sexton, Rachael, MS, Orlowski, Robert Z, Prof, Barlogie, Bart, Prof, Dispenzieri, Angela, Prof

“…Summary Background Lenalidomide plus dexamethasone is a reference treatment for patients with newly diagnosed myeloma. The combination of the proteasome…”
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Curing myeloma at last: defining criteria and providing the evidence by Barlogie, Bart, Mitchell, Alan, van Rhee, Frits, Epstein, Joshua, Morgan, Gareth J., Crowley, John

“…Does the dogma that multiple myeloma is incurable still hold?. The genomic chaos and resulting resistance to apoptosis of myeloma, long considered an obstacle…”
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Controlling pandemic flu: the value of international air travel restrictions by Epstein, Joshua M, Goedecke, D Michael, Yu, Feng, Morris, Robert J, Wagener, Diane K, Bobashev, Georgiy V

“…Planning for a possible influenza pandemic is an extremely high priority, as social and economic effects of an unmitigated pandemic would be devastating…”
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Privacy and contact tracing efficacy by Benthall, Sebastian, Hatna, Erez, Epstein, Joshua M, Strandburg, Katherine J

“…As the COVID-19 pandemic emerged, public health authorities and software designers considered the possibility that smartphones could be used for contact…”
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Generating Mixed Patterns of Residential Segregation: An Evolutionary Approach by Gunaratne, Chathika, Hatna, Erez, Epstein, Joshua M., Garibay, Ivan

“…The Schelling model of residential segregation has demonstrated that even the slightest preference for neighbors of the same race can be amplified into…”
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Modeling civil violence: an agent-based computational approach by Epstein, Joshua M

“…This article presents an agent-based computational model of civil violence. Two variants of the civil violence model are presented. In the first a central…”
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Clonal selection and double-hit events involving tumor suppressor genes underlie relapse in myeloma by Weinhold, Niels, Ashby, Cody, Rasche, Leo, Chavan, Shweta S., Stein, Caleb, Stephens, Owen W., Tytarenko, Ruslana, Bauer, Michael A., Meissner, Tobias, Deshpande, Shayu, Patel, Purvi H., Buzder, Timea, Molnar, Gabor, Peterson, Erich A., van Rhee, Frits, Zangari, Maurizio, Thanendrarajan, Sharmilan, Schinke, Carolina, Tian, Erming, Epstein, Joshua, Barlogie, Bart, Davies, Faith E., Heuck, Christoph J., Walker, Brian A, Morgan, Gareth J.

“…To elucidate the mechanisms underlying relapse from chemotherapy in multiple myeloma, we performed a longitudinal study of 33 patients entered into Total…”
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Simulating the Simultaneous Impact of Medication for Opioid Use Disorder and Naloxone on Opioid Overdose Death in Eight New York Counties by Cerdá, Magdalena, Hamilton, Ava D, Hyder, Ayaz, Rutherford, Caroline, Bobashev, Georgiy, Epstein, Joshua M, Hatna, Erez, Krawczyk, Noa, El-Bassel, Nabila, Feaster, Daniel J, Keyes, Katherine M

“…The United States is in the midst of an opioid overdose epidemic; 28.3 per 100,000 people died of opioid overdose in 2020. Simulation models can help…”
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Special Section on "Inverse Generative Social Science": Guest Editors’ Statement by Epstein, Joshua M., Garibay, Ivan, Hatna, Erez, Koehler, Matthew, Rand, William

“…This is a guest editors' statement accompanying the publication of a special issue on "Inverse Generative Social Science", published in volume 26, issue 2,…”
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Data analysis and modeling pipelines for controlled networked social science experiments by Cedeno-Mieles, Vanessa, Hu, Zhihao, Ren, Yihui, Deng, Xinwei, Contractor, Noshir, Ekanayake, Saliya, Epstein, Joshua M, Goode, Brian J, Korkmaz, Gizem, Kuhlman, Chris J, Machi, Dustin, Macy, Michael, Marathe, Madhav V, Ramakrishnan, Naren, Saraf, Parang, Self, Nathan

“…There is large interest in networked social science experiments for understanding human behavior at-scale. Significant effort is required to perform data…”
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F18-fluorodeoxyglucose positron emission tomography in the context of other imaging techniques and prognostic factors in multiple myeloma by Bartel, Twyla B., Haessler, Jeff, Brown, Tracy L.Y., Shaughnessy, John D., van Rhee, Frits, Anaissie, Elias, Alpe, Terri, Angtuaco, Edgardo, Walker, Ronald, Epstein, Joshua, Crowley, John, Barlogie, Bart

“…F18-fluorodeoxyglucose positron emission tomography (FDG-PET) is a powerful tool to investigate the role of tumor metabolic activity and its suppression by…”
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Combining Computational Fluid Dynamics and Agent-Based Modeling: a new approach to evacuation planning by Epstein, Joshua M, Pankajakshan, Ramesh, Hammond, Ross A

“…We introduce a novel hybrid of two fields-Computational Fluid Dynamics (CFD) and Agent-Based Modeling (ABM)-as a powerful new technique for urban evacuation…”
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The presence of large focal lesions is a strong independent prognostic factor in multiple myeloma by Rasche, Leo, Angtuaco, Edgardo J., Alpe, Terri L., Gershner, Grant H., McDonald, James E., Samant, Rohan S., Kumar, Manoj, Van Hemert, Rudy, Epstein, Joshua, Deshpande, Shayu, Tytarenko, Ruslana, Yaccoby, Shmuel, Hillengass, Jens, Thanendrarajan, Sharmilan, Schinke, Carolina, van Rhee, Frits, Zangari, Maurizio, Walker, Brian A., Barlogie, Bart, Morgan, Gareth J., Davies, Faith E., Weinhold, Niels

“…Spatial intratumor heterogeneity is frequently seen in multiple myeloma (MM) and poses a significant challenge for risk classifiers, which rely on tumor…”
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MAF protein mediates innate resistance to proteasome inhibition therapy in multiple myeloma by Qiang, Ya-Wei, Ye, Shiqiao, Chen, Yu, Buros, Amy F., Edmonson, Ricky, van Rhee, Frits, Barlogie, Bart, Epstein, Joshua, Morgan, Gareth J., Davies, Faith E.

“…Multiple myeloma (MM) patients with the t(14;16) translocation have a poor prognosis, and unlike other molecular subgroups, their outcome has not improved with…”
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