Search Results - "Epshtein, Anastasiya"

Swi2/Snf2-Related Translocases Prevent Accumulation of Toxic Rad51 Complexes during Mitotic Growth by Shah, Parisha P., Zheng, Xiuzhong, Epshtein, Anastasiya, Carey, Jeffrey N., Bishop, Douglas K., Klein, Hannah L.

“…Purified DNA translocases Rdh54 and Rad54 can dissociate complexes formed by eukaryotic RecA-like recombinases on double-stranded DNA. Here, we show that Rad51…”
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Roles of DNA helicases and Exo1 in the avoidance of mutations induced by Top1-mediated cleavage at ribonucleotides in DNA by Niu, Hengyao, Potenski, Catherine J., Epshtein, Anastasiya, Sung, Patrick, Klein, Hannah L.

“…The replicative DNA polymerases insert ribonucleotides into DNA at a frequency of approximately 1/6500 nucleotides replicated. The rNMP residues make the DNA…”
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Yeast Recombination Factor Rdh54 Functionally Interacts with the Rad51 Recombinase and Catalyzes Rad51 Removal from DNA by Chi, Peter, Kwon, Youngho, Seong, Changhyun, Epshtein, Anastasiya, Lam, Isabel, Sung, Patrick, Klein, Hannah L.

“…The Saccharomyces cerevisiae RDH54-encoded product, a member of the Swi2/Snf2 protein family, is needed for mitotic and meiotic interhomologue recombination…”
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Increased Spontaneous Recombination in RNase H2-Deficient Cells Arises From Multiple Contiguous rNMPs and Not From Single rNMP Residues Incorporated by DNA Polymerase Epsilon by Epshtein, Anastasiya, Potenski, Catherine J, Klein, Hannah L

“…Ribonucleotides can become embedded in DNA from insertion by DNA polymerases, failure to remove Okazaki fragment primers, R-loops that can prime replication,…”
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Genome instability consequences of RNase H2 Aicardi-Goutières syndrome alleles by Potenski, Catherine J., Epshtein, Anastasiya, Bianco, Christopher, Klein, Hannah L.

“…•AGS mutations in RNase H2 subunits can be modeled in yeast.•Some AGS alleles have no observable phenotype in yeast.•Other AGS alleles have strong negative…”
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Intrachromosomal Recombination in Yeast by Epshtein, Anastasiya, Symington, Lorraine S, Klein, Hannah L

“…Spontaneous and induced mitotic recombinations are driven by lesions such as single-strand nicks and gaps and double-strand breaks in the genome. For regions…”
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Guidelines for DNA recombination and repair studies: Cellular assays of DNA repair pathways by Klein, Hannah L, Bačinskaja, Giedrė, Che, Jun, Cheblal, Anais, Elango, Rajula, Epshtein, Anastasiya, Fitzgerald, Devon M, Gómez-González, Belén, Khan, Sharik R, Kumar, Sandeep, Leland, Bryan A, Marie, Léa, Mei, Qian, Miné-Hattab, Judith, Piotrowska, Alicja, Polleys, Erica J, Putnam, Christopher D, Radchenko, Elina A, Saada, Anissia Ait, Sakofsky, Cynthia J, Shim, Eun Yong, Stracy, Mathew, Xia, Jun, Yan, Zhenxin, Yin, Yi, Aguilera, Andrés, Argueso, Juan Lucas, Freudenreich, Catherine H, Gasser, Susan M, Gordenin, Dmitry A, Haber, James E, Ira, Grzegorz, Jinks-Robertson, Sue, King, Megan C, Kolodner, Richard D, Kuzminov, Andrei, Lambert, Sarah Ae, Lee, Sang Eun, Miller, Kyle M, Mirkin, Sergei M, Petes, Thomas D, Rosenberg, Susan M, Rothstein, Rodney, Symington, Lorraine S, Zawadzki, Pawel, Kim, Nayun, Lisby, Michael, Malkova, Anna

“…Understanding the plasticity of genomes has been greatly aided by assays for recombination, repair and mutagenesis. These assays have been developed in…”
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Analyses of the yeast Rad51 recombinase A265V mutant reveal different in vivo roles of Swi2-like factors by Chi, Peter, Kwon, YoungHo, Visnapuu, Mari-Liis, Lam, Isabel, Santa Maria, Sergio R, Zheng, Xiuzhong, Epshtein, Anastasiya, Greene, Eric C, Sung, Patrick, Klein, Hannah L

“…The Saccharomyces cerevisiae Swi2-like factors Rad54 and Rdh54 play multifaceted roles in homologous recombination via their DNA translocase activity. Aside…”
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