Search Results - "Epple, Raja"

Memory CD8+ T Cells Balance Pro- and Anti-inflammatory Activity by Reprogramming Cellular Acetate Handling at Sites of Infection by Balmer, Maria L., Ma, Eric H., Thompson, Andrew J., Epple, Raja, Unterstab, Gunhild, Lötscher, Jonas, Dehio, Philippe, Schürch, Christian M., Warncke, Jan D., Perrin, Gaëlle, Woischnig, Anne-Kathrin, Grählert, Jasmin, Löliger, Jordan, Assmann, Nadine, Bantug, Glenn R., Schären, Olivier P., Khanna, Nina, Egli, Adrian, Bubendorf, Lukas, Rentsch, Katharina, Hapfelmeier, Siegfried, Jones, Russell G., Hess, Christoph

“…Serum acetate increases upon systemic infection. Acutely, assimilation of acetate expands the capacity of memory CD8+ T cells to produce IFN-γ. Whether acetate…”
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SDHA gain-of-function engages inflammatory mitochondrial retrograde signaling via KEAP1–Nrf2 by Burgener, Anne-Valérie, Bantug, Glenn R., Meyer, Benedikt J., Higgins, Rebecca, Ghosh, Adhideb, Bignucolo, Olivier, Ma, Eric H., Loeliger, Jordan, Unterstab, Gunhild, Geigges, Marco, Steiner, Rebekah, Enamorado, Michel, Ivanek, Robert, Hunziker, Danielle, Schmidt, Alexander, Müller-Durovic, Bojana, Grählert, Jasmin, Epple, Raja, Dimeloe, Sarah, Lötscher, Jonas, Sauder, Ursula, Ebnöther, Monika, Burger, Bettina, Heijnen, Ingmar, Martínez-Cano, Sarai, Cantoni, Nathan, Brücker, Rolf, Kahlert, Christian R., Sancho, David, Jones, Russell G., Navarini, Alexander, Recher, Mike, Hess, Christoph

“…Whether screening the metabolic activity of immune cells facilitates discovery of molecular pathology remains unknown. Here we prospectively screened the…”
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