Search Results - "Eppinger, Jörg"

Bioprospecting of Novel Extremozymes From Prokaryotes-The Advent of Culture-Independent Methods by Sysoev, Maksim, Grötzinger, Stefan W, Renn, Dominik, Eppinger, Jörg, Rueping, Magnus, Karan, Ram

“…Extremophiles are remarkable organisms that thrive in the harshest environments on Earth, such as hydrothermal vents, hypersaline lakes and pools, alkaline…”
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Poly(3-hydroxybutyrate) production in an integrated electromicrobial setup: Investigation under stress-inducing conditions by Al Rowaihi, Israa Salem, Paillier, Alexis, Rasul, Shahid, Karan, Ram, Grötzinger, Stefan Wolfgang, Takanabe, Kazuhiro, Eppinger, Jörg

“…Poly(3-hydroxybutyrate) (PHB), a biodegradable polymer, can be produced by different microorganisms. The PHB belongs to the family of polyhydroxyalkanoate…”
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Crystal Structure and Active Site Engineering of a Halophilic γ-Carbonic Anhydrase by Vogler, Malvina, Karan, Ram, Renn, Dominik, Vancea, Alexandra, Vielberg, Marie-Theres, Grötzinger, Stefan W, DasSarma, Priya, DasSarma, Shiladitya, Eppinger, Jörg, Groll, Michael, Rueping, Magnus

“…Environments previously thought to be uninhabitable offer a tremendous wealth of unexplored microorganisms and enzymes. In this paper, we present the discovery…”
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Identification and Experimental Characterization of an Extremophilic Brine Pool Alcohol Dehydrogenase from Single Amplified Genomes by Grötzinger, Stefan W, Karan, Ram, Strillinger, Eva, Bader, Stefan, Frank, Annika, Al Rowaihi, Israa S, Akal, Anastassja, Wackerow, Wiebke, Archer, John A, Rueping, Magnus, Weuster-Botz, Dirk, Groll, Michael, Eppinger, Jörg, Arold, Stefan T

“…Because only 0.01% of prokaryotic genospecies can be cultured and in situ observations are often impracticable, culture-independent methods are required to…”
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Robust and Versatile Host Protein for the Design and Evaluation of Artificial Metal Centers by Fischer, Johannes, Renn, Dominik, Quitterer, Felix, Radhakrishnan, Anand, Liu, Meina, Makki, Arwa, Ghorpade, Seema, Rueping, Magnus, Arold, Stefan T, Groll, Michael, Eppinger, Jörg

“…Artificial metalloenzymes (ArMs) have high potential in biotechnological applications as they combine the versatility of transition-metal catalysis with the…”
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Probing the reaction mechanism of IspH protein by x-ray structure analysis by Gräwert, Tobias, Span, Ingrid, Eisenreich, Wolfgang, Rohdich, Felix, Eppinger, Jörg, Bacher, Adelbert, Groll, Michael

“…Isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) represent the two central intermediates in the biosynthesis of isoprenoids. The recently…”
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cis-Tetrachlorido-bis(indazole)osmium(iv) and its osmium(iii) analogues: paving the way towards the cis-isomer of the ruthenium anticancer drugs KP1019 and/or NKP1339 by Büchel, Gabriel E, Kossatz, Susanne, Sadique, Ahmad, Rapta, Peter, Zalibera, Michal, Bucinsky, Lukas, Komorovsky, Stanislav, Telser, Joshua, Eppinger, Jörg, Reiner, Thomas, Arion, Vladimir B

“…The relationship between cis-trans isomerism and anticancer activity has been mainly addressed for square-planar metal complexes, in particular, for…”
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Structure of Active IspH Enzyme from Escherichia coli Provides Mechanistic Insights into Substrate Reduction by Gräwert, Tobias, Rohdich, Felix, Span, Ingrid, Bacher, Adelbert, Eisenreich, Wolfgang, Eppinger, Jörg, Groll, Michael

“…The terminal step of the non‐mevalonate pathway of terpene biosynthesis is catalyzed by IspH (see scheme). In the crystal structure of IspH from E. coli, a…”
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Biosynthesis of Isoprenoids: Crystal Structure of the [4Fe–4S] Cluster Protein IspG by Lee, Matthias, Gräwert, Tobias, Quitterer, Felix, Rohdich, Felix, Eppinger, Jörg, Eisenreich, Wolfgang, Bacher, Adelbert, Groll, Michael

“…IspG protein serves as the penultimate enzyme of the recently discovered non-mevalonate pathway for the biosynthesis of the universal isoprenoid precursors,…”
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Formic Acid as a Hydrogen Energy Carrier by Eppinger, Jörg, Huang, Kuo-Wei

“…The high volumetric capacity (53 g H2/L) and its low toxicity and flammability under ambient conditions make formic acid a promising hydrogen energy carrier…”
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Electronic and Magnetic Properties of Infinite 1D Chains of Paddlewheel Carboxylates M2(COOR)4 (M = Mo, W, Ru, Rh, Ir, Cu) by Peskov, Maxim V, Miao, Xiao-He, Heryadi, Dodi, Eppinger, Jörg, Schwingenschlögl, Udo

“…Dinuclear complexes of transition metals bridged by four carboxylate-groups are examples of stable atomic configurations serving as fundamental building blocks…”
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Palladium N(CH2CH2P i Pr2)2-Dialkylamides: Synthesis, Structural Characterization, and Reactivity by Marziale, Alexander N, Herdtweck, Eberhardt, Eppinger, Jörg, Schneider, Sven

“…Palladium(II) aminodiphosphine PNP pincer complexes [PdR(PNP H )]PF6 (1 R ; R = Cl Me, Ph; PNP H = HN(CH2CH2P i Pr2)2) were prepared. Deprotonation with KO t…”
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A Saccharomyces cerevisiae assay system to investigate ligand/AdipoR1 interactions that lead to cellular signaling by Aouida, Mustapha, Kim, Kangchang, Shaikh, Abdul Rajjak, Pardo, Jose M, Eppinger, Jörg, Yun, Dae-Jin, Bressan, Ray A, Narasimhan, Meena L

“…Adiponectin is a mammalian hormone that exerts anti-diabetic, anti-cancer and cardioprotective effects through interaction with its major ubiquitously…”
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Metal‐Conjugated Affinity Labels: A New Concept to Create Enantioselective Artificial Metalloenzymes by Reiner, Thomas, Jantke, Dominik, Marziale, Alexander N., Raba, Andreas, Eppinger, Jörg

“…How to train a protein: Metal‐conjugated affinity labels were used to selectively position catalytically active metal centers in the binding pocket of…”
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Near-Infrared Intraoperative Chemiluminescence Imaging by Büchel, Gabriel E., Carney, Brandon, Shaffer, Travis M., Tang, Jun, Austin, Christine, Arora, Manish, Zeglis, Brian M., Grimm, Jan, Eppinger, Jörg, Reiner, Thomas

“…Intraoperative imaging technologies recently entered the operating room, and their implementation is revolutionizing how physicians plan, monitor, and perform…”
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Enzyme family-specific and activity-based screening of chemical libraries using enzyme microarrays by Funeriu, Daniel P, Eppinger, Jörg, Denizot, Lucile, Miyake, Masato, Miyake, Jun

“…The potential of protein microarrays in high-throughput screening (HTS) still remains largely unfulfilled, essentially because of the difficulty of extracting…”
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Alkyl Complexes of Rare-Earth Metal Centers Supported by Chelating 1,1′-Diamidoferrocene Ligands: Synthesis, Structure, and Application in Methacrylate Polymerization by Eppinger, Jörg, Nikolaides, Katharina R, Zhang-Presse, Mei, Riederer, Florian A, Rabe, Gerd W, Rheingold, Arnold L

“…Conversion of 1,1′-dianilinoferrocenes of the composition [3,4-R2C5H2(NHPh)]2Fe (R = H, Ph) with 1 equiv of the rare-earth metal alkyl precursors…”
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S-functionalized MXenes as electrode materials for Li-ion batteries by Zhu, Jiajie, Chroneos, Alexander, Eppinger, Jörg, Schwingenschlögl, Udo

“…[Display omitted] •Zr2CS2 MXenes are promising electrode materials for Li-ion batteries.•S groups can be introduced by reaction with CS2 in solution.•S groups…”
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Enzyme Microarrays: On-Chip Determination of Inhibition Constants Based on Affinity-Label Detection of Enzymatic Activity by Eppinger, Jörg, Funeriu, Daniel P., Miyake, Masato, Denizot, Lucile, Miyake, Jun

“…High‐throughput screening of libraries of potential inhibitors is possible by using an enzyme microarray method that combines low sample consumption with…”
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Engineering a Polyspecific Pyrrolysyl-tRNA Synthetase by a High Throughput FACS Screen by Hohl, Adrian, Karan, Ram, Akal, Anastassja, Renn, Dominik, Liu, Xuechao, Ghorpade, Seema, Groll, Michael, Rueping, Magnus, Eppinger, Jörg

“…The Pyrrolysyl-tRNA synthetase (PylRS) and its cognate tRNA Pyl are extensively used to add non-canonical amino acids (ncAAs) to the genetic code of bacterial…”
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