Search Results - "Eppinga, Wietse S C"

Comparing conVEntional RadioTherapy with stereotactIC body radiotherapy in patients with spinAL metastases: study protocol for an randomized controlled trial following the cohort multiple randomized controlled trial design by van der Velden, Joanne M, Verkooijen, Helena M, Seravalli, Enrica, Hes, Jochem, Gerlich, A Sophie, Kasperts, Nicolien, Eppinga, Wietse S C, Verlaan, Jorrit-Jan, van Vulpen, Marco

“…Standard radiotherapy is the treatment of first choice in patients with symptomatic spinal metastases, but is only moderately effective. Stereotactic body…”
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Long-term Local Control and Overall Survival After Radiotherapy in Oligoprogressive Patients During Treatment With Checkpoint Inhibitors by DAMEN, PIM J.J., SUIJKERBUIJK, KARIJN P.M., VAN LINDERT, ANNE S.R., EPPINGA, WIETSE S.C., EL SHAROUNI, SHERIF Y., VERHOEFF, JOOST J.C.

“…Background/Aim: Recent studies described the safety and clinical utility of combined anti-programmed cell death protein-1 (anti-PD1) checkpoint inhibition with…”
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Superior target delineation for stereotactic body radiotherapy of bone metastases from renal cell carcinoma on MRI compared to CT by Prins, Fieke M, van der Velden, Joanne M, Gerlich, Anne S, Kotte, Alexis N T J, Eppinga, Wietse S C, Kasperts, Nicolien, Verlaan, Jorrit J, Pameijer, Frank A, Kerkmeijer, Linda G W

“…In metastatic renal cell carcinoma (mRCC) there has been a treatment shift towards targeted therapy, which has resulted in improved overall survival…”
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Pain Response After Stereotactic Body Radiation Therapy Versus Conventional Radiation Therapy in Patients With Bone Metastases—A Phase 2 Randomized Controlled Trial Within a Prospective Cohort by Pielkenrood, Bart J., van der Velden, Joanne M., van der Linden, Yvette M., Bartels, Marcia M.T., Kasperts, Nicolien, Verhoeff, Joost J.C., Eppinga, Wietse S.C., Gal, Roxanne, Verlaan, Jorrit J., Verkooijen, H.M. (Lenny)

“…Pain response after conventional external beam radiation therapy (cRT) in patients with painful bone metastases is observed in 60% to 70% of patients. The aim…”
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Feasibility of stereotactic radiotherapy using a 1.5 T MR-linac: Multi-fraction treatment of pelvic lymph node oligometastases by Werensteijn-Honingh, Anita M., Kroon, Petra S., Winkel, Dennis, Aalbers, Ellart M., van Asselen, Bram, Bol, Gijsbert H., Brown, Kevin J., Eppinga, Wietse S.C., van Es, Corine A., Glitzner, Markus, de Groot-van Breugel, Eline N., Hackett, Sara L., Intven, Martijn, Kok, Jan G.M., Kontaxis, Charis, Kotte, Alexis N., Lagendijk, Jan J.W., Philippens, Mariëlle E.P., Tijssen, Rob H.N., Wolthaus, Jochem W.H., Woodings, Simon J., Raaymakers, Bas W., Jürgenliemk-Schulz, Ina M.

“…•5 patients with pelvic lymph node metastases received SBRT using a 1.5 T MR-linac.•Session time was <60 min for all 25 treatment fractions.•All quality…”
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Adaptive radiotherapy: The Elekta Unity MR-linac concept by Winkel, Dennis, Bol, Gijsbert H., Kroon, Petra S., van Asselen, Bram, Hackett, Sara S., Werensteijn-Honingh, Anita M., Intven, Martijn P.W., Eppinga, Wietse S.C., Tijssen, Rob H.N., Kerkmeijer, Linda G.W., de Boer, Hans C.J., Mook, Stella, Meijer, Gert J., Hes, Jochem, Willemsen-Bosman, Mirjam, de Groot-van Breugel, Eline N., Jürgenliemk-Schulz, Ina M., Raaymakers, Bas W.

“…•The Elekta Unity MR-linac adaptive radiotherapy concept is explained.•The adapt to shape and adapt to position workflows are compared.•Different methods for…”
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MRI-Guided Ultrafocal Salvage High-Dose-Rate Brachytherapy for Localized Radiorecurrent Prostate Cancer: Updated Results of 50 Patients by van Son, Marieke Juliet, Peters, Max, Moerland, Marinus A., Lagendijk, Jan J.W., Eppinga, Wietse S.C., Shah, Taimur T., Ahmed, Hashim U., van der Voort van Zyp, Jochem R.N.

“…Most patients with local prostate cancer recurrence after radiation therapy undergo palliative androgen deprivation therapy because whole-gland salvage…”
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Target coverage and dose criteria based evaluation of the first clinical 1.5T MR-linac SBRT treatments of lymph node oligometastases compared with conventional CBCT-linac treatment by Winkel, Dennis, Bol, Gijsbert H., Werensteijn-Honingh, Anita M., Intven, Martijn P.W., Eppinga, Wietse S.C., Hes, Jochem, Snoeren, Louk M.W., Sikkes, Gonda G., Gadellaa-van Hooijdonk, Christa G.M., Raaymakers, Bas W., Jürgenliemk-Schulz, Ina M., Kroon, Petra S.

“…•Single and multiple lymph node oligometastases were treated using a 1.5T MR-linac.•The clinically delivered MR-linac plans were compared with CBCT-linac…”
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Remineralization of lytic spinal metastases after radiotherapy by Pielkenrood, Bart J., Visser, Thomas F., van Tol, Floris R., Foppen, Wouter, Eppinga, Wietse S.C., Verhoeff, Joost J.C., Bol, Gijs H., Van der Velden, Joanne M., Verlaan, Jorrit-Jan

“…Palliative radiotherapy (RT) can lead to remineralization of osteolytic lesions thereby potentially restoring some of the weight-bearing capacity and…”
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MRI-Guided Ultrafocal HDR Brachytherapy for Localized Prostate Cancer: Median 4-Year Results of a feasibility study by Peters, Max, van Son, Marieke J., Moerland, Marinus A., Kerkmeijer, Linda G.W., Eppinga, Wietse S.C., Meijer, Richard P., Lagendijk, Jan J.W., Shah, Taimur T., Ahmed, Hashim U., van der Voort van Zijp, Jochem R.N.

“…For the treatment of localized prostate cancer, focal therapy has the potential to cure with fewer side effects than traditional whole-gland treatments. We…”
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Impact of a vacuum cushion on intrafraction motion during online adaptive MR-guided SBRT for pelvic and para-aortic lymph node oligometastases by Werensteijn-Honingh, Anita M., Jürgenliemk-Schulz, Ina M., Gadellaa-Van Hooijdonk, Christa G., Sikkes, Gonda G., Vissers, Nicole G.P.M., Winkel, Dennis, Eppinga, Wietse S.C., Intven, Martijn, Raaymakers, Bas W., Kroon, Petra S.

“…•Vacuum cushion immobilization reduced intrafraction motion in posterior direction.•Most intrafraction motion occurred in the first 16 minutes.•On an MR-linac,…”
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Early Tissue Effects of Stereotactic Body Radiation Therapy for Spinal Metastases by Steverink, Jasper G., Willems, Stefan M., Philippens, Marielle E.P., Kasperts, Nicolien, Eppinga, Wietse S.C., Versteeg, Anne L., van der Velden, Joanne M., Faruqi, Salman, Sahgal, Arjun, Verlaan, Jorrit-Jan

“…Stereotactic body radiation therapy (SBRT) is a highly effective and potentially ablative treatment for complex spinal metastases. Recent data have suggested…”
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Dosimetric feasibility of hypofractionation for SBRT treatment of lymph node oligometastases on the 1.5T MR-linac by Winkel, Dennis, Werensteijn-Honingh, Anita M., Eppinga, Wietse S.C., Intven, Martijn P.W., Hes, Jochem, Snoeren, Louk M.W., Visser, Sanne A., Bol, Gijsbert H., Raaymakers, Bas W., Jürgenliemk-Schulz, Ina M., Kroon, Petra S.

“…•Lymph node oligometastases were treated using a 1.5T MR-linac with a 5x7 Gy scheme.•Hypofractionated schedules were investigated based on dose criteria and…”
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Progression-free survival in patients with 68 Ga-PSMA-PET-directed SBRT for lymph node oligometastases by Werensteijn-Honingh, Anita M, Wevers, Anne F J, Peters, Max, Kroon, Petra S, Intven, Martijn, Eppinga, Wietse S C, Jürgenliemk-Schulz, Ina M

“…Prostate cancer oligometastatic disease can be treated using stereotactic body radiotherapy (SBRT) in order to postpone start of systemic treatments such as…”
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The use of a simultaneous integrated boost in spinal stereotactic body radiotherapy to reduce the risk of vertebral compression fractures: a treatment planning study by van der Velden, Joanne M, Hes, Jochem, Sahgal, Arjun, Hoogcarspel, Stan J, Philippens, Marielle E P, Eppinga, Wietse S C, Seravalli, Enrica

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Prostate-specific Membrane Antigen Positron Emission Tomography/Computed Tomography Is Associated with Improved Oncological Outcome in Men Treated with Salvage Radiation Therapy for Biochemically Recurrent Prostate Cancer by Meijer, Dennie, Eppinga, Wietse S.C., Mohede, Roos M., Vanneste, Ben G.L., Meijnen, Philip, Meijer, Otto W.M., Daniels, Laurien A., van den Bergh, Roderick C.N., Lont, Anne P., Ettema, Rosemarijn H., Oudshoorn, Frederik H.K., van Leeuwen, Pim J., van der Poel, Henk G., Donswijk, Maarten L., Oprea-Lager, Daniela E., Schaake, Eva E., Vis, André N.

“…Patients who underwent restaging prostate-specific membrane antigen positron emission tomography/computed tomography (PSMA-PET/CT) for biochemically recurrent…”
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Bringing online adaptive radiotherapy to a standard C-arm linac by Groot Koerkamp, Maureen L., Bol, Gijsbert H., Kroon, Petra S., Krikke, Lean L., Harderwijk, Tessa, Zoetelief, Annelies J., Scheeren, Annick, van der Vegt, Stefan, Plat, Annika, Hes, Jochem, van Gasteren, Ineke B.A., Renders, Esmee R.T., Rutgers, Reijer H.A., Kok, Saskia W., van Kaam, Joost, Schimmel-de Kogel, Geja J., Sikkes, Gonda G., Winkel, Dennis, van Rijssel, Michael J., Wopereis, André J.M., Ishakoglu, Kübra, Noteboom, Juus L., van der Voort van Zyp, Jochem R.N., Beck, Naomi, Soeterik, Timo F.W., van de Pol, Sandrine M.G., Eppinga, Wietse S.C., van Es, Corine A., Raaymakers, Bas W.

“…•We developed an online adaptive radiotherapy (oART) workflow.•The oART workflow is cone-beam computed tomography-guided.•The oART workflow can be performed on…”
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Clinical utility of convolutional neural networks for treatment planning in radiotherapy for spinal metastases by Arends, Sebastiaan R.S., Savenije, Mark H.F., Eppinga, Wietse S.C., van der Velden, Joanne M., van den Berg, Cornelis A.T., Verhoeff, Joost J.C.

“…•We presented a CNN workflow for segmentation and labeling of vertebrae on CT.•This approach proved to be robust in a majority of cases with spinal…”
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Online adaptive MR-guided radiotherapy: Conformity of contour adaptation for prostate cancer, rectal cancer and lymph node oligometastases among radiation therapists and radiation oncologists by Rasing, Marnix J.A., Sikkes, Gonda G., Vissers, Nicole G.P.M., Kotte, Alexis N.T.J., Boudewijn, Joske H., Doornaert, Patricia A.H., Eppinga, Wietse S.C., Intven, Martijn, Rutgers, Reijer H.A., Scheeren, Annick, Snoeren, Louk M.W., Vlig, Tiny B., van der Voort van Zyp, Jochem R.N., Wijkhuizen, Lisa M., van Rossum, Peter S.N., Peters, Max, Jürgenliemk-Schulz, Ina M.

“…•Contour adaptation conformity analyzed for LN-metastases, rectal- + prostate cancer.•Contour adaptation conformity among RTTs and radiation oncologists is…”
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Evaluation of plan adaptation strategies for stereotactic radiotherapy of lymph node oligometastases using online magnetic resonance image guidance by Winkel, Dennis, Bol, Gijsbert H., Werensteijn-Honingh, Anita M., Kiekebosch, Ilse H., van Asselen, Bram, Intven, Martijn P.W., Eppinga, Wietse S.C., Raaymakers, Bas W., Jürgenliemk-Schulz, Ina M., Kroon, Petra S.

“…Recent studies have shown that the use of magnetic resonance (MR) guided online plan adaptation yields beneficial dosimetric values and reduces unplanned…”
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