Search Results - "Eppig, Janan T."

Mammalian Phenotype Ontology as a unifying standard for experimental and high-throughput phenotyping data by Smith, Cynthia L, Eppig, Janan T

“…The Mammalian Phenotype Ontology (MP) is a structured vocabulary for describing mammalian phenotypes and serves as a critical tool for efficient annotation and…”
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Global genetic analysis in mice unveils central role for cilia in congenital heart disease by Li, You, Klena, Nikolai T., Gabriel, George C., Liu, Xiaoqin, Kim, Andrew J., Lemke, Kristi, Chen, Yu, Chatterjee, Bishwanath, Devine, William, Damerla, Rama Rao, Chang, Chienfu, Yagi, Hisato, San Agustin, Jovenal T., Thahir, Mohamed, Anderton, Shane, Lawhead, Caroline, Vescovi, Anita, Pratt, Herbert, Morgan, Judy, Haynes, Leslie, Smith, Cynthia L., Eppig, Janan T., Reinholdt, Laura, Francis, Richard, Leatherbury, Linda, Ganapathiraju, Madhavi K., Tobita, Kimimasa, Pazour, Gregory J., Lo, Cecilia W.

“…A forward genetic screen in fetal mice to identify genes involved in congenital heart disease (CHD) reveals that a large proportion of genes associated with…”
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Mouse Genome Database (MGD)-2017: community knowledge resource for the laboratory mouse by Blake, Judith A, Eppig, Janan T, Kadin, James A, Richardson, Joel E, Smith, Cynthia L, Bult, Carol J

“…The Mouse Genome Database (MGD: http://www.informatics.jax.org) is the primary community data resource for the laboratory mouse. It provides a highly…”
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The Mouse Genome Database: integration of and access to knowledge about the laboratory mouse by Blake, Judith A, Bult, Carol J, Eppig, Janan T, Kadin, James A, Richardson, Joel E

“…The Mouse Genome Database (MGD) (http://www.informatics.jax.org) is the community model organism database resource for the laboratory mouse, a premier animal…”
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The Human Phenotype Ontology project: linking molecular biology and disease through phenotype data by Köhler, Sebastian, Doelken, Sandra C, Mungall, Christopher J, Bauer, Sebastian, Firth, Helen V, Bailleul-Forestier, Isabelle, Black, Graeme C M, Brown, Danielle L, Brudno, Michael, Campbell, Jennifer, FitzPatrick, David R, Eppig, Janan T, Jackson, Andrew P, Freson, Kathleen, Girdea, Marta, Helbig, Ingo, Hurst, Jane A, Jähn, Johanna, Jackson, Laird G, Kelly, Anne M, Ledbetter, David H, Mansour, Sahar, Martin, Christa L, Moss, Celia, Mumford, Andrew, Ouwehand, Willem H, Park, Soo-Mi, Riggs, Erin Rooney, Scott, Richard H, Sisodiya, Sanjay, Van Vooren, Steven, Wapner, Ronald J, Wilkie, Andrew O M, Wright, Caroline F, Vulto-van Silfhout, Anneke T, de Leeuw, Nicole, de Vries, Bert B A, Washingthon, Nicole L, Smith, Cynthia L, Westerfield, Monte, Schofield, Paul, Ruef, Barbara J, Gkoutos, Georgios V, Haendel, Melissa, Smedley, Damian, Lewis, Suzanna E, Robinson, Peter N

“…The Human Phenotype Ontology (HPO) project, available at http://www.human-phenotype-ontology.org, provides a structured, comprehensive and well-defined set of…”
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The Mouse Genome Database (MGD): facilitating mouse as a model for human biology and disease by Eppig, Janan T, Blake, Judith A, Bult, Carol J, Kadin, James A, Richardson, Joel E

“…The Mouse Genome Database (MGD, http://www.informatics.jax.org) serves the international biomedical research community as the central resource for integrated…”
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The mammalian phenotype ontology: enabling robust annotation and comparative analysis by Smith, Cynthia L., Eppig, Janan T.

“…The mouse has long been an important model for the study of human genetic disease. Through the application of genetic engineering and mutagenesis techniques,…”
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Mouse Genome Informatics (MGI) Resource: Genetic, Genomic, and Biological Knowledgebase for the Laboratory Mouse by Eppig, Janan T.

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Disease Ontology: improving and unifying disease annotations across species by Bello, Susan M, Shimoyama, Mary, Mitraka, Elvira, Laulederkind, Stanley J F, Smith, Cynthia L, Eppig, Janan T, Schriml, Lynn M

“…Model organisms are vital to uncovering the mechanisms of human disease and developing new therapeutic tools. Researchers collecting and integrating relevant…”
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The International Mouse Strain Resource (IMSR): cataloging worldwide mouse and ES cell line resources by Eppig, Janan T., Motenko, Howie, Richardson, Joel E., Richards-Smith, Beverly, Smith, Cynthia L.

“…The availability of and access to quality genetically defined, health-status known mouse resources is critical for biomedical research. By ensuring that mice…”
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Expanding the mammalian phenotype ontology to support automated exchange of high throughput mouse phenotyping data generated by large-scale mouse knockout screens by Smith, Cynthia L, Eppig, Janan T

“…A vast array of data is about to emerge from the large scale high-throughput mouse knockout phenotyping projects worldwide. It is critical that this…”
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Beyond knockouts: cre resources for conditional mutagenesis by Murray, Stephen A, Eppig, Janan T, Smedley, Damian, Simpson, Elizabeth M, Rosenthal, Nadia

“…With the effort of the International Phenotyping Consortium to produce thousands of strains with conditional potential gathering steam, there is growing…”
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Gene Ontology: tool for the unification of biology by Botstein, David, Cherry, J. Michael, Ashburner, Michael, Ball, Catherine A, Blake, Judith A, Butler, Heather, Davis, Allan P, Dolinski, Kara, Dwight, Selina S, Eppig, Janan T, Harris, Midori A, Hill, David P, Issel-Tarver, Laurie, Kasarskis, Andrew, Lewis, Suzanna, Matese, John C, Richardson, Joel E, Ringwald, Martin, Rubin, Gerald M, Sherlock, Gavin

“…Genomic sequencing has made it clear that a large fraction of the genes specifying the core biological functions are shared by all eukaryotes. Knowledge of the…”
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Mouse Genome Informatics (MGI) Resource: Genetic, Genomic, and Biological Knowledgebase for the Laboratory Mouse by Eppig, Janan T.

“…Abstract The Mouse Genome Informatics (MGI) Resource supports basic, translational, and computational research by providing high-quality, integrated data on…”
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Allele, phenotype and disease data at Mouse Genome Informatics: improving access and analysis by Bello, Susan M., Smith, Cynthia L., Eppig, Janan T.

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Mouse Genome Database: From sequence to phenotypes and disease models by Eppig, Janan T., Richardson, Joel E., Kadin, James A., Smith, Cynthia L., Blake, Judith A., Bult, Carol J.

“…Summary The Mouse Genome Database (MGD, www.informatics.jax.org) is the international scientific database for genetic, genomic, and biological data on the…”
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Towards BioDBcore: a community-defined information specification for biological databases by Gaudet, Pascale, Bairoch, Amos, Field, Dawn, Sansone, Susanna-Assunta, Taylor, Chris, Attwood, Teresa K, Bateman, Alex, Blake, Judith A, Bult, Carol J, Cherry, J. Michael, Chisholm, Rex L, Cochrane, Guy, Cook, Charles E, Eppig, Janan T, Galperin, Michael Y, Gentleman, Robert, Goble, Carole A, Gojobori, Takashi, Hancock, John M, Howe, Douglas G, Imanishi, Tadashi, Kelso, Janet, Landsman, David, Lewis, Suzanna E, Mizrachi, Ilene Karsch, Orchard, Sandra, Ouellette, B.F. Francis, Ranganathan, Shoba, Richardson, Lorna, Rocca-Serra, Philippe, Schofield, Paul N, Smedley, Damian, Southan, Christopher, Tan, Tin Wee, Tatusova, Tatiana, Whetzel, Patricia L, White, Owen, Yamasaki, Chisato

“…The present article proposes the adoption of a community-defined, uniform, generic description of the core attributes of biological databases, BioDBCore. The…”
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Inferring gene-to-phenotype and gene-to-disease relationships at Mouse Genome Informatics: challenges and solutions by Bello, Susan M, Eppig, Janan T,

“…Background Inferring gene-to-phenotype and gene-to-human disease model relationships from annotated mouse phenotypes and disease associations is critical when…”
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Mouse Genome Informatics (MGI): Resources for Mining Mouse Genetic, Genomic, and Biological Data in Support of Primary and Translational Research by Eppig, Janan T, Smith, Cynthia L, Blake, Judith A, Ringwald, Martin, Kadin, James A, Richardson, Joel E, Bult, Carol J

“…The Mouse Genome Informatics (MGI), resource ( www.informatics.jax.org ) has existed for over 25 years, and over this time its data content, informatics…”
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Supporting conditional mouse mutagenesis with a comprehensive cre characterization resource by Heffner, Caleb S., Herbert Pratt, C., Babiuk, Randal P., Sharma, Yashoda, Rockwood, Stephen F., Donahue, Leah R., Eppig, Janan T., Murray, Stephen A.

“…Full realization of the value of the loxP -flanked alleles generated by the International Knockout Mouse Consortium will require a large set of…”
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