Search Results - "Epifantseva, Irina"
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Intracellular trafficking pathways of Cx43 gap junction channels
Published in Biochimica et biophysica acta. Biomembranes (01-01-2018)“…Gap Junction (GJ) channels, including the most common Connexin 43 (Cx43), have fundamental roles in excitable tissues by facilitating rapid transmission of…”
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GJA1-20k Arranges Actin to Guide Cx43 Delivery to Cardiac Intercalated Discs
Published in Circulation research (13-10-2017)“…RATIONALE:Delivery of Cx43 (connexin 43) to the intercalated disc is a continuous and rapid process critical for intercellular coupling. By a pathway of…”
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Cx43 Isoform GJA1-20k Promotes Microtubule Dependent Mitochondrial Transport
Published in Frontiers in physiology (07-11-2017)“…Connexin 43 (Cx43, encoded by ) is a cell-cell communication gap junction protein expressed in all organ systems. It was recently found that mRNA undergoes…”
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An Alternatively Translated Connexin 43 Isoform, GJA1-11k, Localizes to the Nucleus and Can Inhibit Cell Cycle Progression
Published in Biomolecules (Basel, Switzerland) (20-03-2020)“…Connexin 43 (Cx43) is a gap junction protein that assembles at the cell border to form intercellular gap junction (GJ) channels which allow for cell-cell…”
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Abstract 235: GJA1-11k Localizes to the Nucleus and Inhibits Cell Cycle Progression
Published in Circulation research (21-07-2017)“…Abstract only Gap Junction (GJ) channels, including the most common Connexin 43 (Cx43), are involved in the exchange of ions and small molecules to maintain…”
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Variation in the lysyl oxidase (LOX) gene is associated with keratoconus in family-based and case-control studies
Published in Investigative ophthalmology & visual science (28-06-2012)“…Keratoconus is a bilateral noninflammatory progressive corneal disorder with complex genetic inheritance and a common cause for cornea transplantation in young…”
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Enhanced wound healing, kinase and stem cell marker expression in diabetic organ-cultured human corneas upon MMP-10 and cathepsin F gene silencing
Published in Investigative ophthalmology & visual science (17-12-2013)“…Diabetic corneas overexpress proteinases including matrix metalloproteinase-10 (M10) and cathepsin F (CF). Our purpose was to assess if silencing M10 and CF in…”
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Abstract 307: GJA1-20k Regulates Actin Cytoskeleton and Promotes Delivery of Connexin 43 to Cardiac Intercalated Discs
Published in Circulation research (21-07-2017)“…Abstract only Rationale: Delivery of connexin 43 (Cx43) to the intercalated disc is a continuous and rapid process critical for intercellular coupling. By a…”
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Induced Pluripotent Stem Cell Based Models of CMT1A and HNPP (P1.066)
Published in Neurology (08-04-2014)“…Abstract only…”
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Induced Pluripotent Stem Cell Based Models of CMT1A and HNPP (I6-2.004)
Published in Neurology (08-04-2014)“…Abstract only…”
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Cell transplantation strategies for acquired and inherited disorders of peripheral myelin
Published in Annals of clinical and translational neurology (01-02-2018)“…Objective To investigate transplantation of rat Schwann cells or human iPSC‐derived neural crest cells and derivatives into models of acquired and inherited…”
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Generation and characterization of a Gdf1 conditional null allele
Published in Genesis (New York, N.Y. : 2000) (01-07-2008)“…Growth differentiation factor‐1 (GDF1), a TGF‐β superfamily member, participates in early embryo patterning. Later functions are implied by the Gdf1 expression…”
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