Search Results - "Epifanova, Ekaterina A."
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Overexpression of Brain- and Glial Cell Line-Derived Neurotrophic Factors Is Neuroprotective in an Animal Model of Acute Hypobaric Hypoxia
Published in International journal of molecular sciences (27-08-2022)“…Currently, the role of the neurotrophic factors BDNF and GDNF in maintaining the brain’s resistance to the damaging effects of hypoxia and functional recovery…”
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AAV-Syn-BDNF-EGFP Virus Construct Exerts Neuroprotective Action on the Hippocampal Neural Network during Hypoxia In Vitro
Published in International journal of molecular sciences (05-08-2018)“…Brain-derived neurotrophic factor (BDNF) is one of the key signaling molecules that supports the viability of neural cells in various brain pathologies, and…”
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Intracellular Neuroprotective Mechanisms in Neuron-Glial Networks Mediated by Glial Cell Line-Derived Neurotrophic Factor
Published in Oxidative medicine and cellular longevity (2019)“…Glial cell line-derived neurotrophic factor (GDNF) has a pronounced neuroprotective effect in various nervous system pathologies, including ischaemic brain…”
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The Influence of Neurotrophic Factors BDNF and GDNF Overexpression on the Functional State of Mice and Their Adaptation to Audiogenic Seizures
Published in Brain sciences (04-08-2022)“…The high prevalence of diagnosed cases of severe neurological disorders, a significant proportion of which are epilepsy, contributes to a high level of…”
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Brain-Derived Neurotrophic Factor (BDNF) Preserves the Functional Integrity of Neural Networks in the β-Amyloidopathy Model in vitro
Published in Frontiers in cell and developmental biology (08-07-2020)“…Alzheimer's disease (AD) is a widespread chronic neurodegenerative pathology characterized by synaptic dysfunction, partial neuronal death, cognitive decline…”
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Mutation in the Sip1 transcription factor leads to a disturbance of the preconditioning of AMPA receptors by episodes of hypoxia in neurons of the cerebral cortex due to changes in their activity and subunit composition. The protective effects of interleukin-10
Published in Archives of biochemistry and biophysics (15-09-2018)“…The Sip1 mutation plays the main role in pathogenesis of the Mowat-Wilson syndrome, which is characterized by the pronounced epileptic symptoms. Cortical…”
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Interleukin-10 restores glutamate receptor-mediated Ca 2+ -signaling in brain circuits under loss of Sip1 transcription factor
Published in International journal of neuroscience (01-02-2022)“…This study aimed to investigate the connection between the mutation of the transcription factor and impaired Ca -signaling, which reflects changes in…”
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NUMERICAL ANALYSIS OF DEFORMATIONS OF THE LIGHTING MAST BY GROUND LASER SCANNING AND FINITE ELEMENTS METHOD
Published in Izvestiâ Tomskogo politehničeskogo universiteta. Inžiniring georesursov (01-05-2019)“…The topic is relevant due to the necessity to improve approaches to estimation and prediction of deformations of the lighting mast. Thesolution of this problem…”
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Sip-1 mutations cause disturbances in the activity of NMDA- and AMPA-, but not kainate receptors of neurons in the cerebral cortex
Published in Neuroscience letters (22-05-2017)“…•Sip1 haploinsufficiency causes higher neuronal sensitivity to NMDA- and AMPA-receptors.•Sip1 homozygosity causes resistance to activation of NMDA- and AMPA…”
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DEFINITION OF DEFORMATIONS OF STEEL VERTICAL CYLINDRICAL RESERVOIR WITH VOLUME OF V=10000 m³ FOR OIL USING TERRESTRIAL LASER SCANNING
Published in Izvestiâ Tomskogo politehničeskogo universiteta. Inžiniring georesursov (01-11-2020)“…The relevance of the topic is caused by the need to develop new approaches to assessing and forecasting structural changes in the space of critical engineering…”
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Interleukin-10 restores glutamate receptor-mediated Ca2+-signaling in brain circuits under loss of Sip1 transcription factor
Published in International journal of neuroscience (30-12-2021)“…This study aimed to investigate the connection between the mutation of the Sip1 transcription factor and impaired Ca 2+ -signaling, which reflects changes in…”
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Interleukin-10 restores glutamate receptor-mediated Ca(2+)-signaling in brain circuits under loss of Sip1 transcription factor
Published 01-02-2022“…OBJECTIVE: This study aimed to investigate the connection between the mutation of the Sip1 transcription factor and impaired Ca(2+)-signaling, which reflects…”
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ASSESSMENT OF SUFFOSION IN THE TERRITORY OF SETTLEMENT SABETTA, THE YAMAL PENINSULA
Published in Izvestiâ Tomskogo politehničeskogo universiteta. Inžiniring georesursov (01-07-2021)“…Relevance. The active development of the Yamal Peninsula leads to the transformation of the geological environment, often accompanied by the activation of…”
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Evaluation of deformation of the historic building in Tomsk by the integrated approach based on terrestrial laser scanner and finite element modeling
Published in Izvestiâ Tomskogo politehničeskogo universiteta. Inžiniring georesursov (01-01-2018)“…The topic is relevant due to the necessity to improve approaches to estimation and prediction of deformations of historical constructions. The article deals…”
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Numerical analysis of bridge foundation behaviour on the old railway line
Published in Izvestiâ Tomskogo politehničeskogo universiteta. Inžiniring georesursov (01-08-2017)“…The topic is relevant due to the necessity to improve approaches to estimation and prediction of deformations of structures operating in harsh natural…”
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ОЦЕНКА СУФФОЗИОННОЙ ОПАСНОСТИ ТЕРРИТОРИИ ПОС. САБЕТТА (ПОЛУОСТРОВ ЯМАЛ)
Published in Izvestiâ Tomskogo politehničeskogo universiteta. Inžiniring georesursov (15-07-2021)“…Актуальность. Активное освоение полуострова Ямал приводит к трансформации геологической среды, часто сопровождающейся активизацией природных и техноприродных…”
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АНАЛИЗ ДЕФОРМАЦИЙ ПРОЖЕКТОРНОЙ МАЧТЫ ПРИ ПОМОЩИ НАЗЕМНОГО ЛАЗЕРНОГО СКАНИРОВАНИЯ И МЕТОДА КОНЕЧНЫХ ЭЛЕМЕНТОВ
Published in Izvestiâ Tomskogo politehničeskogo universiteta. Inžiniring georesursov (13-05-2019)“…Актуальность темы обусловлена необходимостью усовершенствования подходов к оценке и прогнозу деформаций высокомачтовых опор. Решение этой задачи сопряжено с…”
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