Search Results - "Epand, R.M."

Membrane-Active Peptides and the Clustering of Anionic Lipids by Wadhwani, P., Epand, R.F., Heidenreich, N., Bürck, J., Ulrich, A.S., Epand, R.M.

“…There is some overlap in the biological activities of cell-penetrating peptides (CPPs) and antimicrobial peptides (AMPs). We compared nine AMPs, seven CPPs,…”
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The mechanism of lamellar-to-inverted hexagonal phase transitions in phosphatidylethanolamine: implications for membrane fusion mechanisms by Siegel, D.P., Epand, R.M.

“…We studied the mechanism of the lamellar-to-inverted hexagonal (L alpha/H[II]) phase transition, using time-resolved cryotransmission electron microscopy…”
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DSC studies on interactions between low molecular mass peptide dendrimers and model lipid membranes by Klajnert, B., Janiszewska, J., Urbanczyk-Lipkowska, Z., Bryszewska, M., Epand, R.M.

“…It has recently been shown that a newly synthesized peptide dendrimers possess antimicrobial activity against Gram-positive ( Staphylococcus aureus) and…”
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Lipopeptaibols, a novel family of membrane active, antimicrobial peptides by Toniolo, C, Crisma, M, Formaggio, F, Peggion, C, Epand, R F, Epand, R M

“…Lipopeptaibols are members of a novel group of naturally occurring, short peptides with antimicrobial activity, characterized by a lipophilic acyl chain at the…”
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The oxysterol 3β-hydroxy-5-oxo-5,6-secocholestan-6-al changes the phase behavior and structure of phosphatidylethanolamine–phosphatidylcholine mixtures by Bach, D., Epand, R.F., Epand, R.M., Miller, I.R., Wachtel, E.

“…► Small amounts of PC change PE/oxysterol membrane structure and thermotropic behavior. ► Membrane curvature depends on sterol and phospholipid acyl chain…”
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Osmotically Induced Membrane Tension Modulates Membrane Permeabilization by Class L Amphipathic Helical Peptides: Nucleation Model of Defect Formation by Polozov, I.V., Anantharamaiah, G.M., Segrest, J.P., Epand, R.M.

“…The mechanism of action of lytic peptides on membranes is widely studied and is important in view of potential medical applications. Previously (I. V. Polozov,…”
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Interaction of Influenza Virus Fusion Peptide with Lipid Membranes: Effect of Lysolipid by Ohki, S, Baker, G.A, Page, P.M, McCarty, T.A, Epand, R.M, Bright, F.V

“…The effect of lysophosphatidylcholine (LPC) on lipid vesicle fusion and leakage induced by influenza virus fusion peptides and the peptide interaction with…”
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Role of the position of unsaturation on the phase behavior and intrinsic curvature of phosphatidylethanolamines by Epand, R.M., Fuller, N., Rand, R.P.

“…The bilayer-to-hexagonal phase transition temperatures (T(H)) of di-18:1(C) phosphatidylethanolamine with double bonds at positions 6, 9, and 11 are 37 degrees…”
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Reciprocal effects of apolipoprotein and lytic peptide analogs on membranes. Cross-sectional molecular shapes of amphipathic alpha helixes control membrane stability by Tytler, E M, Segrest, J P, Epand, R M, Nie, S Q, Epand, R F, Mishra, V K, Venkatachalapathi, Y V, Anantharamaiah, G M

“…Apolipoprotein (class A) amphipathic helixes are postulated to act as detergents by virtue of their cross-section being wedge-shaped. Using computer analysis…”
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Amphipathic peptide affects the lateral domain organization of lipid bilayers by Polozov, I.V, Polozova, A.I, Molotkovsky, J.G, Epand, R.M

“…Using lipid-specific fluorescent probes, we studied the effects of amphipathic helical, membrane active peptides of the A- and L-type on membrane domain…”
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Formation of a new stable phase of phosphatidylglycerols by Epand, R.M., Gabel, B., Epand, R.F., Sen, A., Hui, S.W., Muga, A., Surewicz, W.K.

“…Dilauroyl and dimyristoylphosphatidylglycerol (DMPG) form a more stable gel state when aqueous suspensions are incubated several days at low temperature (0–2…”
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PAMAM dendrimers and model membranes: Differential scanning calorimetry studies by Klajnert, B., Epand, R.M.

“…Dendrimers attract much attention as potential drug and gene carriers for intracellular delivery. From this point of view, it is crucial to extend our…”
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Cochleate Assemblies with Antimicrobial Oaks and Lipid Mixtures in Absence of Divalent Cations: Biophysical Properties and Strategies to Overcome Drug Resistance by Epand, R.F., Sarig, H., Ohana, D., Papahadjopoulos-Sternberg, B., Mor, A., Epand, R.M.

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Towards a structure-function analysis of bovine lactoferricin and related tryptophan- and arginine-containing peptides by Vogel, Hans J, Schibli, David J, Jing, Weiguo, Lohmeier-Vogel, Elke M, Epand, Raquel F, Epand, Richard M

“…The iron-binding protein lactoferrin is a multifunctional protein that has antibacterial, antifungal, antiviral, antitumour, anti-inflammatory, and…”
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Mitochondrial Nm23-H4 can switch between phosphotransfer and lipid transfer activities by Schlattner, U., Amoscato, A., Tyuina, Y.Y., Tokarska-Schlattner, M., Rios, S. Ramirez, Boissan, M., Epand, R.F., Epand, R.M., Klein-Seetharaman, J., Lacombe, M.L., Kagan, V.E.

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The oxidized form of cholesterol 3β-hydroxy-5-oxo-5,6-secocholestan-6-al induces structural and thermotropic changes in phospholipid membranes by Bach, D., Epand, R.F., Epand, R.M., Miller, I.R., Wachtel, E.

“…The effect of an oxidized form of cholesterol, 3β-hydroxy-5-oxo-5,6-secocholestan-6-al on the thermotropic and structural properties of phospholipid membranes…”
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OAK-based cochleates as a novel approach to overcome multidrug resistance in bacteria by Livne, L, Epand, R.F, Papahadjopoulos-Sternberg, B, Epand, R.M, Mor, A

“…Antibiotic resistance has become a worldwide medical problem. To find new ways of overcoming this phenomenon, we investigated the role of the membrane-active…”
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Effect of influenza hemagglutinin fusion peptide on lamellar/inverted phase transitions in dipalmitoleoylphosphatidylethanolamine: implications for membrane fusion mechanisms by Siegel, D.P., Epand, R.M.

“…Low mole fractions of viral fusion peptides induce inverted cubic (Q II) phases in dipalmitoleoylphosphatidylethanolamine (DiPoPE), a lipid with unsaturated…”
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The effect of free fatty acids on the thermotropic phase transition of dimyristoyl glycerophosphocholine by Usher, J R, Epand, R M, Papahadjopoulos, D

“…The effect of free fatty acids on the phase transition characteristics and fluidity of bilayers of dimyristoyl glycerophosphocholine were studied by pyrene…”
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Anomalous swelling in phospholipid bilayers is not coupled to the formation of a ripple phase by Mason, P C, Nagle, J F, Epand, R M, Katsaras, J

“…Aligned stacks of monomethyl and dimethyl dimyristoyl phosphatidylethanolamine (DMPE) lipid bilayers, like the much studied dimyristoyl PC (DMPC) bilayers,…”
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