Search Results - "Eom, Soomin"

Load and Display: Engineering Encapsulin as a Modular Nanoplatform for Protein-Cargo Encapsulation and Protein-Ligand Decoration Using Split Intein and SpyTag/SpyCatcher by Choi, Hyukjun, Eom, Soomin, Kim, Han-ul, Bae, Yoonji, Jung, Hyun Suk, Kang, Sebyung

“…Protein cage nanoparticles have a unique spherical hollow structure that provides a modifiable interior space and an exterior surface. For full application, it…”
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Development of Recombinant Immunoglobulin G‑Binding Luciferase-Based Signal Amplifiers in Immunoassays by Eom, Soomin, Bae, Yoonji, Kim, Sunghwan, Choi, Hyukjun, Park, Jongnam, Kang, Sebyung

“…In general immunoassays, secondary antibodies are covalently linked with enzymes and bind to the Fc region of target-bound primary antibodies to amplify…”
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Compact and modular bioprobe: Integrating SpyCatcher/SpyTag recombinant proteins with zwitterionic polymer-coated quantum dots by Kim, Sunghwan, Bae, Yoonji, Park, Sung Han, Chen, Ning, Eom, Soomin, Kang, Sebyung, Park, Jongnam

“…[Display omitted] The development of quantum dot (QD)-based modular bioprobe that has a compact size and enable a facile conjugation of various biofunctional…”
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Developing Porous Protein Cage Nanoparticles as Cargo-Loadable and Ligand-Displayable Modular Delivery Nanoplatforms by Eom, Soomin, Jun, Heejin, Kim, Eojin, Min, Duyoung, Kim, Hansol, Kang, Sebyung

“…Protein cage nanoparticles, self-assembled from protein subunits, provide distinct exterior and interior spaces and can carry diagnostic and/or therapeutic…”
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HRP-conjugated plug-and-playable IgG-binding nanobodies as secondary antibody mimics in immunoassays by Bae, Yoonji, Jang, Dong Gil, Eom, Soomin, Park, Tae Joo, Kang, Sebyung

“…•IgG-binding nanobody-based secondary antibody mimics are established using SpyTag/SpyCatcher protein ligation system.•Both HRP:MG1Nb and HRP:RNb specifically…”
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Development of recombinant secondary antibody mimics (rSAMs) for immunoassays through genetic fusion of monomeric alkaline phosphatase with antibody binders by Park, Jiyeon, Bae, Yoonji, Eom, Soomin, Choi, Yuha, Lee, Giwook, Kang, Sebyung

“…In conventional immunoassays, a secondary antibody is used to amplify the signal generated by the binding of the primary antibody to the target analyte. Due to…”
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Protein cage nanoparticle-based NK cell-engaging nanodrones (NKeNDs) effectively recruit NK cells to target tumor sites and suppress tumor growth by Park, Seong Guk, Kim, Hyo Jeong, Lee, Hyun Bin, Eom, Soomin, Jun, Heejin, Jang, Yeongim, Park, Sung Ho, Kang, Sebyung

“…Natural killer (NK) cells are innate lymphoid cells that play a pivotal role in anticancer immunity, and significant efforts have been made to develop…”
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Highly sensitive pregnancy test kit via oriented antibody conjugation on brush-type ligand-coated quantum beads by Kim, Sunghwan, Ahn, Yujin, Bae, Yoonji, Woo, Sunyoung, Park, Jungsik, Han, Im kyung, Kim, Hyunhong, Eom, Soomin, Kang, Sebyung, Jung, Woonggyu, Park, Jongnam

“…Lateral flow assays (LFA) enable development of portable and rapid diagnostic kits; however, their capacity to detect low levels of disease markers remains…”
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CD13-targeting and TRAIL-displaying protein nanoparticles effectively induce apoptotic cell death of acute myeloid leukemia, prolonging survival in mouse models by Jun, Heejin, Yeo, Mirae, Jeon, Jun Pyo, Eom, Soomin, Kim, Hyo Jeong, Kim, Yunjung, Jang, Eunjung, Park, Sung Ho, Kim, Eunhee, Kang, Sebyung

“…Acute myeloid leukemia (AML) is a rapidly proliferating blood cancer, necessitating treatments that specifically target and swiftly eradicate it. In this…”
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Lactate oxidase/vSIRPα conjugates efficiently consume tumor-produced lactates and locally produce tumor-necrotic H2O2 to suppress tumor growth by Kang, Yujin, Yeo, Mirae, Choi, Hyukjun, Jun, Heejin, Eom, Soomin, Park, Seong Guk, Yoon, Haejin, Kim, Eunhee, Kang, Sebyung

“…Aggressive tumor formation often leads to excessive anaerobic glycolysis and massive production and accumulation of lactate in the tumor microenvironment…”
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Lactate oxidase/vSIRPα conjugates efficiently consume tumor-produced lactates and locally produce tumor-necrotic H 2 O 2 to suppress tumor growth by Kang, Yujin, Yeo, Mirae, Choi, Hyukjun, Jun, Heejin, Eom, Soomin, Park, Seong Guk, Yoon, Haejin, Kim, Eunhee, Kang, Sebyung

“…Aggressive tumor formation often leads to excessive anaerobic glycolysis and massive production and accumulation of lactate in the tumor microenvironment…”
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