Search Results - "Entrena, J M"

Pharmacology and therapeutic potential of sigma(1) receptor ligands by Cobos, E J, Entrena, J M, Nieto, F R, Cendán, C M, Del Pozo, E

“…Sigma (sigma) receptors, initially described as a subtype of opioid receptors, are now considered unique receptors. Pharmacological studies have distinguished…”
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Sigma-1 receptor inhibition reverses acute inflammatory hyperalgesia in mice: role of peripheral sigma-1 receptors by Tejada, M. A., Montilla-García, A., Sánchez-Fernández, C., Entrena, J. M., Perazzoli, G., Baeyens, J. M., Cobos, E. J.

“…Rationale Sigma-1 (σ 1 ) receptor inhibition ameliorates neuropathic pain by inhibiting central sensitization. However, it is unknown whether σ 1 receptor…”
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Sigma-1 Receptor Agonism Promotes Mechanical Allodynia After Priming the Nociceptive System with Capsaicin by Entrena, J. M., Sánchez-Fernández, C., Nieto, F. R., González-Cano, R., Yeste, S., Cobos, E. J., Baeyens, J. M.

“…Sigma-1 receptor antagonists promote antinociception in several models of pain, but the effects of sigma-1 agonists on nociception (particularly when the…”
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Pharmacology and Therapeutic Potential of Sigma1 Receptor Ligands by Cobos, E., Entrena, J., Nieto, F., Cendan, C., Pozo, E.

“…Sigma () receptors, initially described as a subtype of opioid receptors, are now considered unique receptors. Pharmacological studies have distinguished two…”
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Push and pull reasons underpinning vulnerable young people’s decisions regarding re-engagement with education and training by Portela-Pruaño, A., Rodríguez-Entrena, M.J., Torres-Soto, A., Nieto-Cano, J.M.

“…Leaving school early is an issue of global concern and various measures have been taken to help early school leavers return to and re-engage with education and…”
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Potassium channels and pain: present realities and future opportunities by Ocaña, María, Cendán, Cruz Miguel, Cobos, Enrique José, Entrena, José Manuel, Baeyens, José Manuel

“…Four families of potassium channels with different structures, functional characteristics and pharmacological sensitivity, are distinguished in neurons:…”
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Grip strength in mice with joint inflammation: A rheumatology function test sensitive to pain and analgesia by Montilla-García, Ángeles, Tejada, Miguel Á., Perazzoli, Gloria, Entrena, José M., Portillo-Salido, Enrique, Fernández-Segura, Eduardo, Cañizares, Francisco J., Cobos, Enrique J.

“…Grip strength deficit is a measure of pain-induced functional disability in rheumatic disease. We tested whether this parameter and tactile allodynia, the…”
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Sigma-1 Receptor Antagonists: A New Class of Neuromodulatory Analgesics by Sánchez-Fernández, Cristina, Entrena, José Manuel, Baeyens, José Manuel, Cobos, Enrique José

“…The sigma-1 receptor is a unique ligand-operated chaperone present in key areas for pain control, in both the peripheral and central nervous system. Sigma-1…”
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Contilisant, a Tetratarget Small Molecule for Alzheimer’s Disease Therapy Combining Cholinesterase, Monoamine Oxidase Inhibition, and H3R Antagonism with S1R Agonism Profile by Bautista-Aguilera, Óscar M, Budni, Josiane, Mina, Francielle, Medeiros, Eduarda Behenck, Deuther-Conrad, Winnie, Entrena, José M, Moraleda, Ignacio, Iriepa, Isabel, López-Muñoz, Francisco, Marco-Contelles, José

“…Contilisant, a permeable, antioxidant, and neuroprotectant agent, showing high nM affinity at H3R and excellent inhibition of the monoamine oxidases and…”
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Sigma-1 receptors are essential for capsaicin-induced mechanical hypersensitivity: Studies with selective sigma-1 ligands and sigma-1 knockout mice by Entrena, José Manuel, Cobos, Enrique José, Nieto, Francisco Rafael, Cendán, Cruz Miguel, Gris, Georgia, Del Pozo, Esperanza, Zamanillo, Daniel, Baeyens, José Manuel

“…We evaluated the role of σ1 receptors on capsaicin-induced mechanical hypersensitivity and on nociceptive pain induced by punctate mechanical stimuli, using…”
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Role of sigma-1 receptors in paclitaxel-induced neuropathic pain in mice by Nieto, Francisco Rafael, Cendán, Cruz Miguel, Sánchez-Fernández, Cristina, Cobos, Enrique José, Entrena, José Manuel, Tejada, Miguel Angel, Zamanillo, Daniel, Vela, José Miguel, Baeyens, José Manuel

“…Sigma-1 (σ(1)) receptors play a role in different types of pain and in central sensitization mechanisms; however, it is unknown whether they are involved in…”
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Enhanced antitumor activity of doxorubicin in breast cancer through the use of poly(butylcyanoacrylate) nanoparticles by Cabeza, Laura, Ortiz, Raúl, Arias, José L, Prados, Jose, Ruiz Martínez, Maria Adolfina, Entrena, José M, Luque, Raquel, Melguizo, Consolación

“…The use of doxorubicin (DOX), one of the most effective antitumor molecules in the treatment of metastatic breast cancer, is limited by its low tumor…”
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Tetrodotoxin inhibits the development and expression of neuropathic pain induced by paclitaxel in mice by Nieto, Francisco Rafael, Entrena, José Manuel, Cendán, Cruz Miguel, Pozo, Esperanza Del, Vela, José Miguel, Baeyens, José Manuel

“…We evaluated the effect of low doses of systemically administered tetrodotoxin (TTX) on the development and expression of neuropathic pain induced by…”
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The antinociceptive effect of morphine is reversed by okadaic acid in morphine-naive but not in morphine-tolerant mice by Ocaña, María, Entrena, José M., Baeyens, José M., Del Pozo, Esperanza

“…The activation of specific subtypes of serine/threonine protein phosphatases (PPs) plays a role in the antinociceptive effect of acute morphine, but it is not…”
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