Search Results - "Enrrico Bloise"

Activin A in Mammalian Physiology by Bloise, Enrrico, Ciarmela, Pasquapina, Dela Cruz, Cynthia, Luisi, Stefano, Petraglia, Felice, Reis, Fernando M

“…Activins are dimeric glycoproteins belonging to the transforming growth factor beta superfamily and resulting from the assembly of two beta subunits, which may…”
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Hormones and pathogenesis of uterine fibroids by Reis, Fernando M., MD, PhD, Bloise, Enrrico, DVM, PhD, Ortiga-Carvalho, Tânia M., PhD

“…The role of ovarian steroid hormones in the pathogenesis of uterine fibroids is supported by epidemiological, clinical, and experimental evidence. Estradiol…”
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Impact of Bacterial and Viral Challenge on Multidrug Resistance in First- and Third-Trimester Human Placenta by Lye, Phetcharawan, Bloise, Enrrico, Javam, Mohsen, Gibb, William, Lye, Stephen J, Matthews, Stephen G

“…The ABC transporters P-glycoprotein (P-gp, official gene symbol ABCB1 ) and breast cancer resistance protein (BCRP, official gene symbol ABCG2 ) protect the…”
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Growth factors and myometrium: biological effects in uterine fibroid and possible clinical implications by Ciarmela, Pasquapina, Islam, Md. Soriful, Reis, Fernando M., Gray, Peter C., Bloise, Enrrico, Petraglia, Felice, Vale, Wylie, Castellucci, Mario

“…BACKGROUND Growth factors are proteins secreted by a number of cell types that are capable of modulating cellular growth, proliferation and cellular…”
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Impaired Placental Nutrient Transport in Mice Generated by in Vitro Fertilization by Bloise, Enrrico, Lin, Wingka, Liu, Xiaowei, Simbulan, Rhodel, Kolahi, Kevin S, Petraglia, Felice, Maltepe, Emin, Donjacour, Annemarie, Rinaudo, Paolo

“…More than 4.5 million children have been conceived by in vitro fertilization (IVF). Interestingly, singleton IVF offspring born at term have an increased…”
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Effects of bacterial and viral pathogen-associated molecular patterns (PAMPs) on multidrug resistance (MDR) transporters in brain endothelial cells of the developing human blood-brain barrier by Lye, Phetcharawan, Bloise, Enrrico, Matthews, Stephen G

“…The multidrug resistance (MDR) transporters, P-glycoprotein (P-gp, encoded by ABCB1) and breast cancer resistance protein (BCRP/ABCG2) contribute to the…”
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Hypoxia alters the expression of ACE2 and TMPRSS2 SARS-CoV-2 cell entry mediators in hCMEC/D3 brain endothelial cells by Imperio, Guinever E., Lye, Phetcharawan, Mughis, Hafsah, Hamada, Hirotaka, Bloise, Enrrico, Lye, Stephen J., Matthews, Stephen G.

“…The mechanisms by which the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) induces neurological complications remain to be elucidated. We aimed…”
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Impact of Maternal Malnutrition on Gut Barrier Defense: Implications for Pregnancy Health and Fetal Development by Srugo, Sebastian A, Bloise, Enrrico, Nguyen, Tina Tu-Thu Ngoc, Connor, Kristin L

“…Small intestinal Paneth cells, enteric glial cells (EGC), and goblet cells maintain gut mucosal integrity, homeostasis, and influence host physiology locally…”
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Effect of substrate stiffness on early mouse embryo development by Kolahi, Kevin S, Donjacour, Annemarie, Liu, Xiaowei, Lin, Wingka, Simbulan, Rhodel K, Bloise, Enrrico, Maltepe, Emin, Rinaudo, Paolo

“…It is becoming increasingly clear that cells are remarkably sensitive to the biophysical cues of their microenvironment and that these cues play a significant…”
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ZIKV Disrupts Placental Ultrastructure and Drug Transporter Expression in Mice by Andrade, Cherley Borba Vieira, Monteiro, Victoria Regina de Siqueira, Coelho, Sharton Vinicius Antunes, Gomes, Hanailly Ribeiro, Sousa, Ronny Paiva Campos, Nascimento, Veronica Muller de Oliveira, Bloise, Flavia Fonseca, Matthews, Stephen Giles, Bloise, Enrrico, Arruda, Luciana Barros, Ortiga-Carvalho, Tania Maria

“…Congenital Zika virus (ZIKV) infection can induce fetal brain abnormalities. Here, we investigated whether maternal ZIKV infection affects placental physiology…”
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Immunostaining of βA-Activin and Follistatin Is Decreased in HPV(+) Cervical Pre-Neoplastic and Neoplastic Lesions by Payano, Victor Jesus Huaringa, Lopes, Lara Verônica de Araújo, Peixoto, Larissa Rodrigues, Silva, Keila Alves da, Ortiga-Carvalho, Tania Maria, Tafuri, Alexandre, Vago, Annamaria Ravara, Bloise, Enrrico

“…The activin-follistatin system regulates several cellular processes, including differentiation and tumorigenesis. We hypothesized that the immunostaining of…”
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Chorioamnionitis Induces a Specific Signature of Placental ABC Transporters Associated with an Increase of miR-331-5p in the Human Preterm Placenta by do Imperio, Guinever Eustaquio, Bloise, Enrrico, Javam, Mohsen, Lye, Phetcharawan, Constantinof, Andrea, Dunk, Caroline, dos Reis, Fernando Marcos, Lye, Stephen James, Gibb, William, Ortiga-Carvalho, Tania M., Matthews, Stephen Giles

“…Background/Aims: The ATP-binding cassette (ABC) transporters mediate drug biodisposition and immunological responses in the placental barrier. In vitro…”
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Hypoxia modulates P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP) drug transporters in brain endothelial cells of the developing human blood-brain barrier by Mughis, Hafsah, Lye, Phetcharawan, Imperio, Guinever E., Bloise, Enrrico, Matthews, Stephen G.

“…P-glycoprotein (P-gp) and Breast Cancer Resistance Protein (BCRP) multidrug resistance (MDR) transporters are localized at the luminal surface of the…”
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Acute Effects of Viral Exposure on P-Glycoprotein Function in the Mouse Fetal Blood-Brain Barrier by Bloise, Enrrico, Petropoulos, Sophie, Iqbal, Majid, Kostaki, Alisa, Ortiga-Carvalho, Tania Maria, Gibb, William, Matthews, Stephen G.

“…Background/Aims: Viral infection during pregnancy is known to affect the fetal brain. The toll-like receptor (TLR)-3 is a pattern recognition receptor…”
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Functional Expression of Multidrug-Resistance (MDR) Transporters in Developing Human Fetal Brain Endothelial Cells by Lye, Phetcharawan, Bloise, Enrrico, Imperio, Guinever E, Chitayat, David, Matthews, Stephen G

“…There is little information about the functional expression of the multidrug resistance (MDR) transporters P-glycoprotein (P-gp, encoded by ABCB1) and breast…”
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Effect of Sublethal Prenatal Endotoxaemia on Murine Placental Transport Systems and Lipid Homeostasis by Reginatto, Mila W., Fontes, Klaus Novaes, Monteiro, Victoria R. S., Silva, Natalia L., Andrade, Cherley Borba Vieira, Gomes, Hanailly Ribeiro, Imperio, Guinever E., Bloise, Flavia Fonseca, Kluck, George Eduardo Gabriel, Atella, Georgia Correa, Matthews, Stephen G., Bloise, Enrrico, Ortiga-Carvalho, Tania M.

“…Infection alters the expression of transporters that mediate the placental exchange of xenobiotics, lipids and cytokines. We hypothesized that…”
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Prenatal endotoxemia and placental drug transport in the mouse: placental size-specific effects by Bloise, Enrrico, Bhuiyan, Manzerul, Audette, Melanie C, Petropoulos, Sophie, Javam, Mohsen, Gibb, William, Matthews, Stephen G

“…Lipopolysaccharide (LPS) in high doses inhibits placental multidrug resistance P-glycoprotein (P-gp--Abcb1a/b) and breast cancer resistance protein…”
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Impact of Co-Occurrence of Obesity and SARS-CoV-2 Infection during Pregnancy on Placental Pathologies and Adverse Birth Outcomes: A Systematic Review and Narrative Synthesis by Ferraz, Thaina, Benton, Samantha J, Zareef, Israa, Aribaloye, Oluwatomike, Bloise, Enrrico, Connor, Kristin L

“…Obesity is a risk factor for severe COVID-19 disease during pregnancy. We hypothesized that the co-occurrence of high maternal body mass index (BMI) and…”
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L-type voltage-dependent Ca2+ channels expression involved in pre-neoplastic transformation of breast cancer by Aguiar, Flávia, Rhana, Paula, Bloise, Enrrico, Rodrigues, Andreia Laura Prates, Ferreira, Enio

“…Abstract Background Intracellular Ca2+ levels can modulate several cellular functions, including proliferation and other processes found altered in neoplastic…”
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ACE2 Is Expressed in Immune Cells That Infiltrate the Placenta in Infection-Associated Preterm Birth by Lye, Phetcharawan, Dunk, Caroline E., Zhang, Jianhong, Wei, Yanxing, Nakpu, Jittanan, Hamada, Hirotaka, Imperio, Guinever E., Bloise, Enrrico, Matthews, Stephen G., Lye, Stephen J.

“…COVID-19 is associated with increased incidence of preterm birth (PTB). We assessed pathways by which SARS-CoV-2 could access the placenta. Placentae, from PTB…”
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