Search Results - "Enriz, Ricardo"

Structure activity relationships and the binding mode of quinolinone-pyrimidine hybrids as reversal agents of multidrug resistance mediated by P-gp by Laiolo, Jerónimo, Lanza, Priscila Ailin, Parravicini, Oscar, Barbieri, Cecilia, Insuasty, Daniel, Cobo, Justo, Vera, D. Mariano Adolfo, Enriz, Ricardo Daniel, Carpinella, Maria Cecilia

“…P-gp-associated multidrug resistance is a major impediment to the success of chemotherapy. With the aim of finding non-toxic and effective P-gp inhibitors, we…”
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Theoretical and Experimental Study of Inclusion Complexes of β‑Cyclodextrins with Chalcone and 2′,4′-Dihydroxychalcone by Sancho, Matias I, Andujar, Sebastian, Porasso, Rodolfo D, Enriz, Ricardo D

“…The inclusion complexes formed by chalcone and 2′,4′-dihydroxychalcone with β-cyclodextrin have been studied combining experimental (phase solubility diagrams,…”
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Anti-inflammatory effects and improved metabolic derangements in ob/ob mice by a newly synthesized prenylated benzopyran with pan-PPAR activity by Marques, Patrice, Villarroel-Vicente, Carlos, Collado, Aida, García, Ainhoa, Vila, Laura, Duplan, Isabelle, Hennuyer, Nathalie, Garibotto, Francisco, Enriz, Ricardo D., Dacquet, Catherine, Staels, Bart, Piqueras, Laura, Cortes, Diego, Sanz, María-Jesús, Cabedo, Nuria

“…Selective peroxisome proliferator-activated receptors (PPARs) are widely used to treat metabolic complications; however, the limited effect of PPARα agonists…”
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Benzopyran hydrazones with dual PPARα/γ or PPARα/δ agonism and an anti-inflammatory effect on human THP-1 macrophages by García, Ainhoa, Vila, Laura, Duplan, Isabelle, Schiel, María Ayelén, Enriz, Ricardo D., Hennuyer, Nathalie, Staels, Bart, Cabedo, Nuria, Cortes, Diego

“…Peroxisome proliferator-activated receptors (PPARs) play a major role in regulating inflammatory processes, and dual or pan-PPAR agonists with PPARγ partial…”
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Synthesis of a new 2-prenylated quinoline as potential drug for metabolic syndrome with pan-PPAR activity and anti-inflammatory effects by Villarroel-Vicente, Carlos, García, Ainhoa, Zibar, Khamis, Schiel, María Ayelén, Ferri, Jordi, Hennuyer, Nathalie, Enriz, Ricardo D., Staels, Bart, Cortes, Diego, Cabedo, Nuria

“…[Display omitted] •Synthesis and PPAR activity of 2-prenylated benzopyrans and quinolines.•γ,δ-Unsaturated ester of benzopyran 5a and quinoline 4b showed…”
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Novel Sulfonamide-Based Carbamates as Selective Inhibitors of BChE by Magar, Pratibha, Parravicini, Oscar, Štěpánková, Šárka, Svrčková, Katarina, Garro, Adriana D., Jendrzejewska, Izabela, Pauk, Karel, Hošek, Jan, Jampílek, Josef, Enriz, Ricardo D., Imramovský, Aleš

“…A series of 14 target benzyl [2-(arylsulfamoyl)-1-substituted-ethyl]carbamates was prepared by multi-step synthesis and characterized. All the final compounds…”
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Polycerasoidol, a Natural Prenylated Benzopyran with a Dual PPARα/PPARγ Agonist Activity and Anti-inflammatory Effect by Bermejo, Almudena, Collado, Aida, Barrachina, Isabel, Marqués, Patrice, El Aouad, Noureddine, Franck, Xavier, Garibotto, Francisco, Dacquet, Catherine, Caignard, Daniel H, Suvire, Fernando D, Enriz, Ricardo D, Piqueras, Laura, Figadère, Bruno, Sanz, María-Jesús, Cabedo, Nuria, Cortes, Diego

“…Dual peroxisome proliferator-activated receptor-α/γ (PPARα/γ) agonists regulate both lipid and glucose homeostasis under different metabolic conditions and can…”
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Second generation of pyrimidin-quinolone hybrids obtained from virtual screening acting as sphingosine kinase 1 inhibitors and potential anticancer agents by Vettorazzi, Marcela, Díaz, Iván, Angelina, Emilio, Salido, Sofía, Gutierrez, Lucas, Alvarez, Sergio E., Cobo, Justo, Enriz, Ricardo D.

“…[Display omitted] •We report a virtual screening, design, synthesis and activity of eight new inhibitors of SphK1.•Four compounds displayed anticancer activity…”
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Conformational and electronic study of dopamine interacting with the D2 dopamine receptor by Tosso, Rodrigo D., Parravicini, Oscar, Zarycz, M. Natalia C., Angelina, Emilio, Vettorazzi, Marcela, Peruchena, Nélida, Andujar, Sebastián, Enriz, Ricardo D.

“…We report an exhaustive conformational and electronic study on dopamine (DA) interacting with the D2 dopamine receptor (D2DR). For the first time, the complete…”
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Evaluating the conformational space of the active site of D 2 dopamine receptor. Scope and limitations of the standard docking methods by Tosso, Rodrigo D, Zarycz, M Natalia C, Schiel, Ayelén, Goicoechea Moro, Luisa, Baldoni, Héctor A, Angelina, Emilio, Enriz, Ricardo D

“…We report here for the first time the potential energy surfaces (PES) of phenyletilamine (PEA) and meta-tyramine (m-OH-PEA) at the D dopamine receptor (D2DR)…”
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Synthesis, Analysis, Cholinesterase-Inhibiting Activity and Molecular Modelling Studies of 3-(Dialkylamino)-2-hydroxypropyl 4-[(Alkoxy-carbonyl)amino]benzoates and Their Quaternary Ammonium Salts by Padrtova, Tereza, Marvanova, Pavlina, Odehnalova, Klara, Kubinova, Renata, Parravicini, Oscar, Garro, Adriana, Enriz, Ricardo D, Humpa, Otakar, Oravec, Michal, Mokry, Petr

“…Tertiary amines 3-(dialkylamino)-2-hydroxypropyl 4-[(alkoxycarbonyl)amino]benzoates and their quaternary ammonium salts were synthesized. The final step of…”
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The Mechanism of Antimicrobial Small-Cationic Peptides from Coarse-Grained Simulations by Frigini, Ezequiel N., Porasso, Rodolfo D., Beke-Somfai, Tamás, López Cascales, José Javier, Enriz, Ricardo D., Pantano, Sergio

“…Antimicrobial cationic peptides (AMPs) are excellent candidates for use as therapeutic antimicrobial agents. Among them, short peptides possessing sequences of…”
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Targeting defective sphingosine kinase 1 in Niemann–Pick type C disease with an activator mitigates cholesterol accumulation by Newton, Jason, Palladino, Elisa N.D., Weigel, Cynthia, Maceyka, Michael, Gräler, Markus H., Senkal, Can E., Enriz, Ricardo D., Marvanova, Pavlina, Jampilek, Josef, Lima, Santiago, Milstien, Sheldon, Spiegel, Sarah

“…Niemann–Pick type C (NPC) disease is a lysosomal storage disorder arising from mutations in the cholesterol-trafficking protein NPC1 (95%) or NPC2 (5%). These…”
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Evaluating the conformational space of the active site of D2 dopamine receptor. Scope and limitations of the standard docking methods by Tosso, Rodrigo D., Zarycz, M. Natalia C., Schiel, Ayelén, Goicoechea Moro, Luisa, Baldoni, Héctor A., Angelina, Emilio, Enriz, Ricardo D.

“…We report here for the first time the potential energy surfaces (PES) of phenyletilamine (PEA) and meta‐tyramine (m‐OH‐PEA) at the D2 dopamine receptor (D2DR)…”
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The Antimicrobial Activity of Annona emarginata (Schltdl.) H. Rainer and Most Active Isolated Compounds against Clinically Important Bacteria by Dolab, Juan G, Lima, Beatriz, Spaczynska, Ewelina, Kos, Jiri, Cano, Natividad H, Feresin, Gabriela, Tapia, Alejandro, Garibotto, Francisco, Petenatti, Elisa, Olivella, Monica, Musiol, Robert, Jampilek, Josef, Enriz, Ricardo D

“…(Schltdl.) H. Rainer, commonly known as "arachichú", "araticú", "aratigú", and "yerba mora", is a plant that grows in Argentina. Infusions and decoctions are…”
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Cholinesterase-inhibitory effect and in silico analysis of alkaloids from bulbs of Hieronymiella species by Ortiz, Javier E., Garro, Adriana, Pigni, Natalia B., Agüero, María Belén, Roitman, German, Slanis, Alberto, Enriz, Ricardo D., Feresin, Gabriela E., Bastida, Jaume, Tapia, Alejandro

“…In Argentina, the Amaryllidaceae family (59 species) comprises a wide variety of genera, only a few species have been investigated as a potential source of…”
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Exploring the interaction of N-(benzothiazol-2-yl)pyrrolamide DNA gyrase inhibitors with the GyrB ATP-binding site lipophilic floor: A medicinal chemistry and QTAIM study by Zidar, Nace, Emanuel Cotman, Andrej, Sinnige, Wessel, Benek, Ondrej, Barančokova, Michaela, Zega, Anamarija, Peterlin Mašič, Lucija, Tomašič, Tihomir, Ilaš, Janez, Henderson, Sara R., Mundy, Julia E.A., Maxwell, Anthony, Stevenson, Clare E.M., Lawson, David M., Jan Sterk, Geert, Tosso, Rodrigo, Gutierrez, Lucas, Enriz, Ricardo D., Kikelj, Danijel

“…[Display omitted] •The interactions of benzothiazole GyrB inhibitors with the lipophilic floor of the active site were studied.•The inhibition of E. coli GyrB…”
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Synthesis and antifungal activity of ( Z)-5-arylidenerhodanines by Sortino, Maximiliano, Delgado, Paula, Juárez, Sabina, Quiroga, Jairo, Abonía, Rodrigo, Insuasty, Braulio, Nogueras, Manuel, Rodero, Laura, Garibotto, Francisco M., Enriz, Ricardo D., Zacchino, Susana A.

“…New benciliden-rhodanines of the general structure A showed fungicidal properties against standardized and clinical fungi displaying potent activities against…”
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Small Cationic Peptides: Influence of Charge on Their Antimicrobial Activity by López Cascales, José Javier, Zenak, Siham, García de la Torre, José, Lezama, Osvaldo Guy, Garro, Adriana, Enriz, Ricardo Daniel

“…The first stage of the action mechanism of small cationic peptides with antimicrobial activity is ruled by electrostatic interactions between the peptide and…”
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An integrative study to identify novel scaffolds for sphingosine kinase 1 inhibitors by Vettorazzi, Marcela, Angelina, Emilio, Lima, Santiago, Gonec, Tomas, Otevrel, Jan, Marvanova, Pavlina, Padrtova, Tereza, Mokry, Petr, Bobal, Pavel, Acosta, Lina M., Palma, Alirio, Cobo, Justo, Bobalova, Janette, Csollei, Jozef, Malik, Ivan, Alvarez, Sergio, Spiegel, Sarah, Jampilek, Josef, Enriz, Ricardo D.

“…Sphingosine kinase 1 (SphK1), the enzyme that produces the bioactive sphingolipid metabolite, sphingosine-1-phosphate, is a promising new molecular target for…”
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