Search Results - "Enrique, Andrea"

New anticonvulsant candidates prevent P-glycoprotein (P-gp) overexpression in a pharmacoresistant seizure model in mice by Enrique, Andrea Verónica, Di Ianni, Mauricio Emiliano, Goicoechea, Sofía, Lazarowski, Alberto, Valle-Dorado, María Guadalupe, Costa, Juan José López, Rocha, Luisa, Girardi, Elena, Talevi, Alan

“…Despite the approval of a considerable number of last generation antiepileptic drugs (AEDs) (only in the last decade, six drugs have gained Food and Drug…”
Get full text

Design, synthesis and biological evaluation of N-substituted α-hydroxyimides and 1,2,3-oxathiazolidine-4-one-2,2-dioxides with anticonvulsant activity by Sabatier, Laureano L., Palestro, Pablo H., Enrique, Andrea V., Pastore, Valentina, Sbaraglini, María L., Martín, Pedro, Gavernet, Luciana

“…In this investigation, we studied a family of compounds with an oxathiazolidine-4-one-2,2-dioxide skeleton and their amide synthetic precursors as new…”
Get full text

Parabens inhibit hNaV 1.2 channels by Enrique, Andrea, Martín, Pedro, Sbaraglini, María Laura, Talevi, Alan, Milesi, Verónica

“…[Display omitted] •Propylparaben, butylparaben and benzylparaben inhibit hNaV1.2 channel mediated currents through a voltage- and frequency-dependent…”
Get full text

Anticonvulsant activity of artificial sweeteners: A structural link between sweet-taste receptor T1R3 and brain glutamate receptors by Talevi, Alan, Enrique, Andrea V., Bruno-Blanch, Luis E.

“…Identification of several non-nutritive sweeteners as potential anticonvulsants through virtual screening suggested a structural link between sweet taste…”
Get full text

Computer-Aided Recognition of ABC Transporters Substrates and Its Application to the Development of New Drugs for Refractory Epilepsy by Couyoupetrou, Manuel, Gantner, Melisa E, Di Ianni, Mauricio E, Palestro, Pablo H, Enrique, Andrea V, Gavernet, Luciana, Ruiz, Maria E, Pesce, Guido, Bruno-Blanch, Luis E, Talevi, Alan

“…Despite the introduction of more than 15 third generation antiepileptic drugs to the market from 1990 to the moment, about one third of the epileptic patients…”
Get more information

Novel sulfamides and sulfamates derived from amino esters: Synthetic studies and anticonvulsant activity by Villalba, Maria L., Enrique, Andrea V., Higgs, Josefina, Castaño, Rocío A., Goicoechea, Sofía, Taborda, Facundo D., Gavernet, Luciana, Lick, Ileana D, Marder, Mariel, Bruno Blanch, Luis E.

“…We report herein the design and optimization of a novel series of sulfamides and sulfamates derived from amino esters with anticonvulsant properties. The…”
Get full text

Is there a relationship between sweet taste and seizures? Anticonvulsant and proconvulsant effects of non-nutritive sweeteners by Di Ianni, Mauricio E, Enrique, Andrea V, Del Valle, María E, Aldana, Blanca, Rosella, María A, Rocha, Luisa, Castro, Eduardo A, Bruno-Blanch, Luis E, Talevi, Alan

“…From a virtual screening campaign, a number of artificial and natural sweeteners were predicted as potential anticonvulsant agents with protective effects in…”
Get more information

Several New Diverse Anticonvulsant Agents Discovered in a Virtual Screening Campaign Aimed at Novel Antiepileptic Drugs to Treat Refractory Epilepsy by Di Ianni, Mauricio E, Enrique, Andrea V, Palestro, Pablo H, Gavernet, Luciana, Talevi, Alan, Bruno-Blanch, Luis E

“…A virtual screening campaign was conducted in order to discover new anticonvulsant drug candidates for the treatment of refractory epilepsy. To this purpose, a…”
Get full text

Computer-Aided Identification of Anticonvulsant Effect of Natural Nonnutritive Sweeteners Stevioside and Rebaudioside A by Di Ianni, Mauricio E, Del Valle, María E, Enrique, Andrea V, Rosella, María A, Bruno, Fiorella, Bruno-Blanch, Luis E, Talevi, Alan

“…Steviol glycosides are natural constituents of Stevia rebaudiana (Bert.) Bert. (Asteraceae) that have recently gained worldwide approval as nonnutritive…”
Get more information

New model of pharmacoresistant seizures induced by 3-mercaptopropionic acid in mice by Enrique, Andrea, Goicoechea, Sofía, Castaño, Rocío, Taborda, Facundo, Rocha, Luisa, Orozco, Sandra, Girardi, Elena, Blanch, Luis Bruno

“…Highlights • A new model of pharmacoresistant seizure was developed in mice. • In the new model animals have a high percentage of PHT and PB resistance. •…”
Get full text

N-propyl-2,2-diphenyl-2-hydroxyacetamide, a novel α-hydroxyamide with anticonvulsant, anxiolytic and antidepressant-like effects that inhibits voltage-gated sodium channels by Pastore, Valentina, Wasowski, Cristina, Martin, Pedro, Enrique, Andrea, Higgs, Josefina, Bruno-Blanch, Luis E., Milesi, Veronica, Marder, Mariel

“…In patients with epilepsy, anxiety and depression are the most frequent psychiatric comorbidities but they often remain unrecognized and untreated. We report…”
Get full text

Parabens inhibit hNa V 1.2 channels by Enrique, Andrea, Martín, Pedro, Sbaraglini, María Laura, Talevi, Alan, Milesi, Verónica

“…Propylparaben, a commonly used antimicrobial preservative, has been reported as an anticonvulsant agent targeting neuronal Na channels (Na ). However, the…”
Get full text

Synthesis and anticonvulsant activity of bioisosteres of trimethadione, N-derivative-1,2,3-oxathiazolidine-4-one-2,2-dioxides from α-hydroxyamides by Pastore, Valentina, Sabatier, Laureano, Enrique, Andrea, Marder, Mariel, Bruno-Blanch, Luis E.

“…The synthesis and anticonvulsant activity of novel heterocycles N-derivative-1,2,3-oxathiazolidine-4-one-2,2-dioxides, bioisosteres of trimethadione (TMD,…”
Get full text

Synthesis and anticonvulsant activity of bioisosteres of trimethadione, N-derivative-1,2,3-oxathiazolidine-4-one-2,2-dioxides from [alpha]-hydroxyamides by Pastore, Valentina, Sabatier, Laureano, Enrique, Andrea, Marder, Mariel, Bruno-Blanch, Luis E

“…The synthesis and anticonvulsant activity of novel heterocycles N-derivative-1,2,3-oxathiazolidine-4-one-2,2-dioxides, bioisosteres of trimethadione (TMD,…”
Get full text

Synthesis and anticonvulsant activity of bioisosteres of trimethadione, N-derivative-1,2,3-oxathiazolidine-4-one-2,2-dioxides from I--hydroxyamides by Pastore, Valentina, Sabatier, Laureano, Enrique, Andrea, Marder, Mariel, Bruno-Blanch, Luis

“…The synthesis and anticonvulsant activity of novel heterocycles N-derivative-1,2,3-oxathiazolidine-4-one-2,2-dioxides, bioisosteres of trimethadione (TMD,…”
Get full text

N, N′-Dicyclohexylsulfamide and N, N′-diphenethylsulfamide are anticonvulsant sulfamides with affinity for the benzodiazepine binding site of the GABA A receptor and anxiolytic activity in mice by Wasowski, Cristina, Gavernet, Luciana, Barrios, Ivana A., Villalba, Maria L., Pastore, Valentina, Samaja, Gisela, Enrique, Andrea, Bruno-Blanch, Luis E., Marder, Mariel

“…A set of sulfamides designed, synthesized and evaluated against maximal electroshock seizure (MES) and pentilenetetrazol (PTZ) tests with promising results,…”
Get full text

N,N′-Dicyclohexylsulfamide and N,N′-diphenethylsulfamide are anticonvulsant sulfamides with affinity for the benzodiazepine binding site of the GABAA receptor and anxiolytic activity in mice by Wasowski, Cristina, Gavernet, Luciana, Barrios, Ivana A, Villalba, Maria L, Pastore, Valentina, Samaja, Gisela, Enrique, Andrea, Bruno-Blanch, Luis E, Marder, Mariel

“…A set of sulfamides designed, synthesized and evaluated against maximal electroshock seizure (MES) and pentilenetetrazol (PTZ) tests with promising results,…”
Get full text

N,N&; prime; -Dicyclohexylsulfamide and N,N&; prime; -diphenethylsulfamide are anticonvulsant sulfamides with affinity for the benzodiazepine binding site of the GABA sub(A receptor and anxiolytic activity in mice) by Wasowski, Cristina, Gavernet, Luciana, Barrios, Ivana A, Villalba, Maria L, Pastore, Valentina, Samaja, Gisela, Enrique, Andrea, Bruno-Blanch, Luis E, Marder, Mariel

“…A set of sulfamides designed, synthesized and evaluated against maximal electroshock seizure (MES) and pentilenetetrazol (PTZ) tests with promising results,…”
Get full text

Synthesis and Anticonvulsant Activity of Amino Acid-Derived Sulfamides by Gavernet, Luciana, Elvira, Juan E, Samaja, Gisela A, Pastore, Valentina, Sella Cravero, Mariana, Enrique, Andrea, Estiu, Guillermina, Bruno-Blanch, Luis E

“…Sulfamides are promising functions for the design of new antiepileptic drugs ( Bioorg. Med. Chem. 2007, 15, 1556−1567; 5604−5614). Following previous research…”
Get full text

Reducing Cr6+ in electroplating wastewater with Bacillus cereus strain B1 by Moreno-Benavides, Jennifer Andrea, Peña-Salamanca, Enrique Javier, Benítez-Campo, Neyla

“…In this study Bacillus cereus was used to evaluate the Cr6+ reducing capacity in electroplating effluents. TheCr6+ bioreduction assays were carried out using…”
Get full text