Search Results - "Enright, Jennifer M."
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Cyp27c1 Red-Shifts the Spectral Sensitivity of Photoreceptors by Converting Vitamin A1 into A2
Published in Current biology (07-12-2015)“…Some vertebrate species have evolved means of extending their visual sensitivity beyond the range of human vision. One mechanism of enhancing sensitivity to…”
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Cell Type-Specific Epigenomic Analysis Reveals a Uniquely Closed Chromatin Architecture in Mouse Rod Photoreceptors
Published in Scientific reports (03-03-2017)“…Rod photoreceptors are specialized neurons that mediate vision in dim light and are the predominant photoreceptor type in nocturnal mammals. The rods of…”
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Transcriptome profiling of developing photoreceptor subtypes reveals candidate genes involved in avian photoreceptor diversification
Published in Journal of comparative neurology (1911) (01-03-2015)“…ABSTRACT Avian photoreceptors are a diverse class of neurons, comprised of four single cones, the two members of the double cone, and rods. The signaling…”
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Inhibition of Müller glial cell division blocks regeneration of the light‐damaged zebrafish retina
Published in Developmental neurobiology (Hoboken, N.J.) (15-02-2008)“…The adult zebrafish retina possesses a robust regenerative response. In the light‐damaged retina, Müller glial cell divisions precede regeneration of rod and…”
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Characterization of Müller glia and neuronal progenitors during adult zebrafish retinal regeneration
Published in Experimental eye research (01-11-2008)“…The adult zebrafish retina exhibits a robust regenerative response following light-induced photoreceptor cell death. This response is initiated by the Müller…”
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Pax6a and Pax6b are required at different points in neuronal progenitor cell proliferation during zebrafish photoreceptor regeneration
Published in Experimental eye research (01-05-2010)“…The light-damaged zebrafish retina results in the death of photoreceptor cells and the subsequent regeneration of the missing rod and cone cells. Photoreceptor…”
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Human cytochrome P450 27C1 catalyzes 3,4‐desaturation of retinoids
Published in FEBS letters (01-05-2016)“…In humans, a considerable fraction of the retinoid pool in skin is derived from vitamin A2 (all‐trans 3,4‐dehydroretinal). Vitamin A2 may be locally generated…”
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Fenofibrate Reduces the Severity of Neuroretinopathy in a Type 2 Model of Diabetes without Inducing Peroxisome Proliferator-Activated Receptor Alpha-Dependent Retinal Gene Expression
Published in Journal of clinical medicine (31-12-2020)“…Fenofibrate slows the progression of clinical diabetic retinopathy (DR), but its mechanism of action in the retina remains unclear. Fenofibrate is a known…”
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Cambrian origin of the CYP27C1-mediated vitamin A1-to-A2 switch, a key mechanism of vertebrate sensory plasticity
Published in Royal Society open science (05-07-2017)“…The spectral composition of ambient light varies across both space and time. Many species of jawed vertebrates adapt to this variation by tuning the…”
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Floppy iris syndrome and cataract surgery
Published in Current opinion in ophthalmology (01-01-2017)“…PURPOSE OF REVIEWIntraoperative floppy iris syndrome (IFIS) occurs in 2% of cataract surgeries and is associated with an increased risk of surgical…”
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Severe Spontaneous Tilt of Scleral-Fixated Intraocular Lenses
Published in American journal of ophthalmology (01-06-2024)“…To report and evaluate a multicenter series of 18 cases of severe, spontaneous IOL tilt involving the flanged intrascleral haptic fixation technique (FISHF)…”
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Cambrian origin of the CYP27C1-mediated vitamin A 1 -to-A 2 switch, a key mechanism of vertebrate sensory plasticity
Published in Royal Society open science (01-07-2017)“…The spectral composition of ambient light varies across both space and time. Many species of jawed vertebrates adapt to this variation by tuning the…”
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Pax6 is required for neuronal progenitor cell proliferation during cone cell regeneration
Published in Developmental biology (15-07-2008)Get full text
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Clinicomolecular Identification of Conserved and Individualized Features of Granulomatous Uveitis
Published in Ophthalmology science (Online) (01-03-2021)“…To identify molecular features that distinguish individuals with shared clinical features of granulomatous uveitis. Cross-sectional observational study. Four…”
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