Search Results - "Enos Bernasconi"

Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology by Piccoli, Luca, Park, Young-Jun, Tortorici, M. Alejandra, Czudnochowski, Nadine, Walls, Alexandra C., Beltramello, Martina, Silacci-Fregni, Chiara, Pinto, Dora, Rosen, Laura E., Bowen, John E., Acton, Oliver J., Jaconi, Stefano, Guarino, Barbara, Minola, Andrea, Zatta, Fabrizia, Sprugasci, Nicole, Bassi, Jessica, Peter, Alessia, De Marco, Anna, Nix, Jay C., Mele, Federico, Jovic, Sandra, Rodriguez, Blanca Fernandez, Gupta, Sneha V., Jin, Feng, Piumatti, Giovanni, Lo Presti, Giorgia, Pellanda, Alessandra Franzetti, Biggiogero, Maira, Tarkowski, Maciej, Pizzuto, Matteo S., Cameroni, Elisabetta, Havenar-Daughton, Colin, Smithey, Megan, Hong, David, Lepori, Valentino, Albanese, Emiliano, Ceschi, Alessandro, Bernasconi, Enos, Elzi, Luigia, Ferrari, Paolo, Garzoni, Christian, Riva, Agostino, Snell, Gyorgy, Sallusto, Federica, Fink, Katja, Virgin, Herbert W., Lanzavecchia, Antonio, Corti, Davide, Veesler, David

“…Analysis of the specificity and kinetics of neutralizing antibodies (nAbs) elicited by SARS-CoV-2 infection is crucial for understanding immune protection and…”
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Determinants of HIV-1 reservoir size and long-term dynamics during suppressive ART by Bachmann, Nadine, von Siebenthal, Chantal, Vongrad, Valentina, Turk, Teja, Neumann, Kathrin, Beerenwinkel, Niko, Bogojeska, Jasmina, Fellay, Jaques, Roth, Volker, Kok, Yik Lim, Thorball, Christian W., Borghesi, Alessandro, Parbhoo, Sonali, Wieser, Mario, Böni, Jürg, Perreau, Matthieu, Klimkait, Thomas, Yerly, Sabine, Battegay, Manuel, Rauch, Andri, Hoffmann, Matthias, Bernasconi, Enos, Cavassini, Matthias, Kouyos, Roger D., Günthard, Huldrych F., Metzner, Karin J.

“…The HIV-1 reservoir is the major hurdle to a cure. We here evaluate viral and host characteristics associated with reservoir size and long-term dynamics in…”
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Efficacy and safety of dolutegravir plus emtricitabine versus standard ART for the maintenance of HIV-1 suppression: 48-week results of the factorial, randomized, non-inferiority SIMPL'HIV trial by Sculier, Delphine, Wandeler, Gilles, Yerly, Sabine, Marinosci, Annalisa, Stoeckle, Marcel, Bernasconi, Enos, Braun, Dominique L, Vernazza, Pietro, Cavassini, Matthias, Buzzi, Marta, Metzner, Karin J, Decosterd, Laurent A, Günthard, Huldrych F, Schmid, Patrick, Limacher, Andreas, Egger, Matthias, Calmy, Alexandra

“…Dolutegravir (DTG)-based dual therapy is becoming a new paradigm for both the initiation and maintenance of HIV treatment. The SIMPL'HIV study investigated the…”
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A cluster of multidrug-resistant Mycobacterium tuberculosis among patients arriving in Europe from the Horn of Africa: a molecular epidemiological study by Walker, Timothy M, Merker, Matthias, Knoblauch, Astrid M, Helbling, Peter, Schoch, Otto D, van der Werf, Marieke J, Kranzer, Katharina, Fiebig, Lena, Kröger, Stefan, Haas, Walter, Hoffmann, Harald, Indra, Alexander, Egli, Adrian, Cirillo, Daniela M, Robert, Jérôme, Rogers, Thomas R, Groenheit, Ramona, Mengshoel, Anne T, Mathys, Vanessa, Haanperä, Marjo, Soolingen, Dick van, Niemann, Stefan, Böttger, Erik C, Keller, Peter M, Avsar, Korkut, Bauer, Christoph, Bernasconi, Enos, Borroni, Emanuele, Brusin, Sergio, Coscollá Dévis, Mireia, Crook, Derrick W., Dedicoat, Martin, Fitzgibbon, Margaret, Gagneux, Sébastien, Geiger, Francisca, Guthmann, Jean-Paul, Hendrickx, David, Hoffmann-Thiel, Sabine, van Ingen, Jakko, Jackson, Sarah, Jaton, Katia, Lange, Christoph, Mazza Stalder, Jessica, O'Donnell, Joan, Opota, Onya, Peto, Tim E.A., Preiswerk, Benjamin, Roycroft, Emma, Sato, Mariko, Schacher, Regina, Schulthess, Bettina, Smith, E. Grace, Soini, Hanna, Sougakoff, Wladimir, Tagliani, Elisa, Utpatel, Christian, Veziris, Nicolas, Wagner-Wiening, Christiane, Witschi, Mark

“…The risk of tuberculosis outbreaks among people fleeing hardship for refuge in Europe is heightened. We describe the cross-border European response to an…”
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Safety, immunogenicity, and preliminary clinical efficacy of a vaccine against extraintestinal pathogenic Escherichia coli in women with a history of recurrent urinary tract infection: a randomised, single-blind, placebo-controlled phase 1b trial by Huttner, Angela, Dr, Hatz, Christoph, Prof, van den Dobbelsteen, Germie, PhD, Abbanat, Darren, PhD, Hornacek, Alena, MSc, Frölich, Rahel, BSc, Dreyer, Anita M, PhD, Martin, Patricia, PhD, Davies, Todd, PhD, Fae, Kellen, PhD, van den Nieuwenhof, Ingrid, PhD, Thoelen, Stefan, MD, de Vallière, Serge, MD, Kuhn, Anette, Prof, Bernasconi, Enos, MD, Viereck, Volker, Prof, Kavvadias, Tilemachos, MD, Kling, Kerstin, MD, Ryu, Gloria, MD, Hülder, Tanja, MD, Gröger, Sabine, MD, Scheiner, David, MD, Alaimo, Cristina, PhD, Harbarth, Stephan, MD, Poolman, Jan, PhD, Fonck, Veronica Gambillara, PhD

“…Summary Background Escherichia coli infections are increasing worldwide in community and hospital settings. The E coli O-antigen is a promising vaccine target…”
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Determinants of HIV-1 broadly neutralizing antibody induction by Rusert, Peter, Kouyos, Roger D, Kadelka, Claus, Ebner, Hanna, Schanz, Merle, Huber, Michael, Braun, Dominique L, Hozé, Nathanael, Scherrer, Alexandra, Magnus, Carsten, Weber, Jacqueline, Uhr, Therese, Cippa, Valentina, Thorball, Christian W, Kuster, Herbert, Cavassini, Matthias, Bernasconi, Enos, Hoffmann, Matthias, Calmy, Alexandra, Battegay, Manuel, Rauch, Andri, Yerly, Sabine, Aubert, Vincent, Klimkait, Thomas, Böni, Jürg, Fellay, Jacques, Regoes, Roland R, Günthard, Huldrych F, Trkola, Alexandra

“…Broadly neutralizing antibodies (bnAbs) develop in a minority of HIV-infected individuals. Analyzing data from more than 4,000 infected individuals, Alexandra…”
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CD4:CD8 Ratio and CD8 Cell Count and Their Prognostic Relevance for Coronary Heart Disease Events and Stroke in Antiretroviral Treated Individuals: The Swiss HIV Cohort Study by Chammartin, Frédérique, Darling, Katharine, Abela, Irene A., Battegay, Manuel, Furrer, Hansjakob, Calmy, Alexandra, Bernasconi, Enos, Schmid, Patrick, Hoffmann, Matthias, Bucher, Heiner C.

“…HIV infection leads to a persistent expansion of terminally CD8 T cells and CD8 T suppressor cells, a marker of chronic immune activation leading to a low…”
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SARS-CoV-2 viral shedding among diabetic patients: from upper to lower respiratory tract by Trimboli, Pierpaolo, Bernasconi, Enos, Buetti, Niccolo

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Characterization and Determinants of Long-Term Immune Recovery Under Suppressive Antiretroviral Therapy by Turk, Teja, Labarile, Marco, Braun, Dominique L, Rauch, Andri, Stöckle, Marcel, Cavassini, Matthias, Hoffmann, Matthias, Calmy, Alexandra, Bernasconi, Enos, Notter, Julia, Pasin, Chloé, Günthard, Huldrych F, Kouyos, Roger D

“…We developed a robust characterization of immune recovery trajectories in people living with HIV on antiretroviral treatment (ART) and relate our findings to…”
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Assessing the drivers of syphilis among men who have sex with men in Switzerland reveals a key impact of screening frequency: A modelling study by Balakrishna, Suraj, Salazar-Vizcaya, Luisa, Schmidt, Axel J, Kachalov, Viacheslav, Kusejko, Katharina, Thurnheer, Maria Christine, Roth, Jan A, Nicca, Dunja, Cavassini, Matthias, Battegay, Manuel, Schmid, Patrick, Bernasconi, Enos, Günthard, Huldrych F, Rauch, Andri, Kouyos, Roger D

“…Over the last decade, syphilis diagnoses among men-who-have-sex-with-men (MSM) have strongly increased in Europe. Understanding the drivers of the ongoing…”
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Is breastfeeding an equipoise option in effectively treated HIV-infected mothers in a high-income setting? by Kahlert, Christian, Aebi-Popp, Karoline, Bernasconi, Enos, Martinez de Tejada, Begoña, Nadal, David, Paioni, Paolo, Rudin, Christoph, Staehelin, Cornelia, Wagner, Noémie, Vernazza, Pietro

“…Combined antiretroviral treatment (cART) has reduced mother-to-child transmission (MTCT) of the human immunodeficiency virus (HIV) to virtually zero in…”
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Unsupervised machine learning predicts future sexual behaviour and sexually transmitted infections among HIV-positive men who have sex with men by Andresen, Sara, Balakrishna, Suraj, Mugglin, Catrina, Schmidt, Axel J, Braun, Dominique L, Marzel, Alex, Doco Lecompte, Thanh, Darling, Katharine EA, Roth, Jan A, Schmid, Patrick, Bernasconi, Enos, Günthard, Huldrych F, Rauch, Andri, Kouyos, Roger D, Salazar-Vizcaya, Luisa

“…Machine learning is increasingly introduced into medical fields, yet there is limited evidence for its benefit over more commonly used statistical methods in…”
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A systematic review of hepatitis C virus epidemiology in Europe, Canada and Israel by Cornberg, Markus, Razavi, Homie A., Alberti, Alfredo, Bernasconi, Enos, Buti, Maria, Cooper, Curtis, Dalgard, Olav, Dillion, John F., Flisiak, Robert, Forns, Xavier, Frankova, Sona, Goldis, Adrian, Goulis, Ioannis, Halota, Waldemar, Hunyady, Bela, Lagging, Martin, Largen, Angela, Makara, Michael, Manolakopoulos, Spilios, Marcellin, Patrick, Marinho, Rui T., Pol, Stanislas, Poynard, Thierry, Puoti, Massimo, Sagalova, Olga, Sibbel, Scott, Simon, Krzysztof, Wallace, Carolyn, Young, Kendra, Yurdaydin, Cihan, Zuckerman, Eli, Negro, Francesco, Zeuzem, Stefan

“…Background and Aim: Decisions on public health issues are dependent on reliable epidemiological data. A comprehensive review of the literature was used to…”
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Brief Report: Switching From TDF to TAF in HIV/HBV-Coinfected Individuals With Renal Dysfunction—A Prospective Cohort Study by Surial, Bernard, Béguelin, Charles, Chave, Jean-Philippe, Stöckle, Marcel, Boillat-Blanco, Noémie, Doco-Lecompte, Thanh, Bernasconi, Enos, Fehr, Jan, Günthard, Huldrych F., Schmid, Patrick, Walti, Laura N., Furrer, Hansjakob, Rauch, Andri, Wandeler, Gilles

“…Whereas tenofovir disoproxil fumarate (TDF) can lead to renal adverse events, tenofovir alafenamide (TAF) has a more favorable renal safety profile. However,…”
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A case of spondylodiscitis by Ureaplasma urealyticum in an immunocompetent adult with spine stabilization by Piccinini, Daniele, Bernasconi, Enos, Lucchini, Gladys Martinetti, Benedetto, Caroline Di, Colombo, GianMarco, Bongiovanni, Marco

“…•We present the first case of Ureaplasma urealyticum spondylodiscitis in an immunocompetent man.•U. urealyticum was identified through a broad-spectrum…”
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Diabetes mellitus is a risk factor for prolonged SARS-CoV-2 viral shedding in lower respiratory tract samples of critically ill patients by Buetti, Niccolò, Trimboli, Pierpaolo, Mazzuchelli, Timothy, Lo Priore, Elia, Balmelli, Carlo, Trkola, Alexandra, Conti, Marco, Martinetti, Gladys, Elzi, Luigia, Ceschi, Alessandro, Consonni, Vera, Ogna, Adam, Forni-Ogna, Valentina, Bernasconi, Enos

“…Purpose The length of time a critically ill coronavirus disease 2019 (COVID-19) patient remains infectious and should therefore be isolated remains unknown…”
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SARS-CoV-2 detection in the lower respiratory tract of invasively ventilated ARDS patients by Buetti, Niccolò, Wicky, Paul-Henri, Le Hingrat, Quentin, Ruckly, Stéphane, Mazzuchelli, Timothy, Loiodice, Ambre, Trimboli, Pierpaolo, Forni Ogna, Valentina, de Montmollin, Etienne, Bernasconi, Enos, Visseaux, Benoit, Timsit, Jean-François

“…Data on SARS-CoV-2 load in lower respiratory tract (LRT) are scarce. Our objectives were to describe the viral shedding and the viral load in LRT and to…”
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Increased prevalence of clonal hematopoiesis of indeterminate potential amongst people living with HIV by Bick, Alexander G., Popadin, Konstantin, Thorball, Christian W., Uddin, Md Mesbah, Zanni, Markella V., Yu, Bing, Cavassini, Matthias, Rauch, Andri, Tarr, Philip, Schmid, Patrick, Bernasconi, Enos, Günthard, Huldrych F., Libby, Peter, Boerwinkle, Eric, McLaren, Paul J., Ballantyne, Christie M., Grinspoon, Steven, Natarajan, Pradeep, Fellay, Jacques

“…People living with human immunodeficiency virus (PLWH) have significantly increased risk for cardiovascular disease in part due to inflammation and immune…”
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Using viral diversity to identify HIV-1 variants under HLA-dependent selection in a systematic viral genome-wide screen by Neuner-Jehle, Nadia, Zeeb, Marius, Thorball, Christian W, Fellay, Jacques, Metzner, Karin J, Frischknecht, Paul, Neumann, Kathrin, Leeman, Christine, Rauch, Andri, Stöckle, Marcel, Huber, Michael, Perreau, Matthieu, Bernasconi, Enos, Notter, Julia, Hoffmann, Matthias, Leuzinger, Karoline, Günthard, Huldrych F, Pasin, Chloé, Kouyos, Roger D

“…The pathogenesis of HIV-1 infection is governed by a highly dynamic, time-dependent interaction between the host and the viral genome. In this study, we…”
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Risk assessment and seroprevalence of SARS-CoV-2 infection in healthcare workers of COVID-19 and non-COVID-19 hospitals in Southern Switzerland by Piccoli, Luca, Ferrari, Paolo, Piumatti, Giovanni, Jovic, Sandra, Rodriguez, Blanca Fernandez, Mele, Federico, Giacchetto-Sasselli, Isabella, Terrot, Tatiana, Silacci-Fregni, Chiara, Cameroni, Elisabetta, Jaconi, Stefano, Sprugasci, Nicole, Bartha, Istvan, Corti, Davide, Uguccioni, Mariagrazia, Lanzavecchia, Antonio, Garzoni, Christian, Giannini, Olivier, Bernasconi, Enos, Elzi, Luigia, Albanese, Emiliano, Sallusto, Federica, Ceschi, Alessandro

“…Hospital healthcare workers (HCW), in particular those involved in the clinical care of COVID-19 cases, are presumably exposed to a higher risk of acquiring…”
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