Search Results - "Enoch, David A."

The Changing Epidemiology of Invasive Fungal Infections by Enoch, David A, Yang, Huina, Aliyu, Sani H, Micallef, Christianne

“…Invasive fungal infections (IFI) are an emerging problem worldwide with invasive candidiasis and candidemia responsible for the majority of cases. This is…”
Get more information

Definition of a genetic relatedness cutoff to exclude recent transmission of meticillin-resistant Staphylococcus aureus: a genomic epidemiology analysis by Coll, Francesc, Raven, Kathy E, Knight, Gwenan M, Blane, Beth, Harrison, Ewan M, Leek, Danielle, Enoch, David A, Brown, Nicholas M, Parkhill, Julian, Peacock, Sharon J

“…Whole-genome sequencing (WGS) can be used in genomic epidemiology investigations to confirm or refute outbreaks of bacterial pathogens, and to support targeted…”
Get full text

Efficacy of FFP3 respirators for prevention of SARS-CoV-2 infection in healthcare workers by Ferris, Mark, Ferris, Rebecca, Workman, Chris, O'Connor, Eoin, Enoch, David A, Goldesgeyme, Emma, Quinnell, Natalie, Patel, Parth, Wright, Jo, Martell, Geraldine, Moody, Christine, Shaw, Ashley, Illingworth, Christopher Jr, Matheson, Nicholas J, Weekes, Michael P

“…Respiratory protective equipment recommended in the UK for healthcare workers (HCWs) caring for patients with COVID-19 comprises a fluid-resistant surgical…”
Get full text

Patient and public understanding and knowledge of antimicrobial resistance and stewardship in a UK hospital: should public campaigns change focus? by Micallef, Christianne, Kildonaviciute, Kornelija, Castro-Sánchez, Enrique, Scibor-Stepien, Aleksandra, Santos, Reem, Aliyu, Sani H, Cooke, Fiona J, Pacey, Sarah, Holmes, Alison H, Enoch, David A

“…The rising global tide of antimicrobial resistance is a well-described phenomenon. Employing effective and innovative antimicrobial stewardship strategies is…”
Get full text

Real-World Financial and Clinical Impact of Diagnostic-Driven and Empirical-Treatment Strategies in High-Risk Immunocompromised Patients with Suspected Aspergillus Infection in the United Kingdom by Earnshaw, Stephanie R, McDade, Cheryl, Bryan, Andrew, Ines, Monica, Micallef, Christianne, Sung, Anita, Enoch, David A

“…A diagnostic-driven (DD) treatment strategy has proven successful for treating invasive fungal infections (IFIs) caused by Aspergillus. However, uptake of this…”
Get full text

Erratum for Earnshaw et al., “Real-World Financial and Clinical Impact of Diagnostic-Driven and Empirical-Treatment Strategies in High-Risk Immunocompromised Patients with Suspected Aspergillus Infection in the United Kingdom” by Earnshaw, Stephanie R., McDade, Cheryl, Bryan, Andrew, Ines, Monica, Micallef, Christianne, Sung, Anita, Enoch, David A.

Get full text

Diagnostic tool or screening programme? Asymptomatic testing for SARS-CoV-2 needs clear goals and protocols by Skittrall, Jordan P, Fortune, Mary D, Jalal, Hamid, Zhang, Hongyi, Enoch, David A, Brown, Nicholas M, Swift, Anne

Get full text

Mortality Following Clostridioides difficile Infection in Europe: A Retrospective Multicenter Case-Control Study by Czepiel, Jacek, Krutova, Marcela, Mizrahi, Assaf, Khanafer, Nagham, Enoch, David A, Patyi, Márta, Deptuła, Aleksander, Agodi, Antonella, Nuvials, Xavier, Pituch, Hanna, Wójcik-Bugajska, Małgorzata, Filipczak-Bryniarska, Iwona, Brzozowski, Bartosz, Krzanowski, Marcin, Konturek, Katarzyna, Fedewicz, Marcin, Michalak, Mateusz, Monpierre, Lorra, Vanhems, Philippe, Gouliouris, Theodore, Jurczyszyn, Artur, Goldman-Mazur, Sarah, Wultańska, Dorota, Kuijper, Ed J, Skupień, Jan, Biesiada, Grażyna, Garlicki, Aleksander

“…We aimed to describe the clinical presentation, treatment, outcome and report on factors associated with mortality over a 90-day period in infection (CDI)…”
Get full text

Using Behavior Change Theory to Identify Drivers and Barriers for Antifungal Treatment Decisions: A Case Study in a Large Teaching Hospital in the East of England, UK by Micallef, Christianne, Sung, Anita H., Gheorghe, Maria, Maladwala, Rahael, Grady, Kate, Kouppas, Christian, Enoch, David A.

“…Introduction Antifungal stewardship (AFS) programs are recognized to contribute to optimizing antifungal prescribing for treatment and prophylaxis. However,…”
Get full text

Large-Scale Evaluation of a Rapid Fully Automated Analysis Platform to Detect and Refute Outbreaks Based on MRSA Genome Comparisons by Raven, Kathy E, Bragin, Eugene, Blane, Beth, Leek, Danielle, Kumar, Narender, Rhodes, Paul A, Enoch, David A, Thaxter, Rachel, Brown, Nicholas M, Parkhill, Julian, Peacock, Sharon J

“…Genomic epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) could transform outbreak investigations, but its clinical introduction is hampered…”
Get full text

Screening urine samples for the absence of urinary tract infection using the sediMAX automated microscopy analyser by Sterry-Blunt, Rosanne E, S Randall, Karen, J Doughton, Michael, H Aliyu, Sani, A Enoch, David

“…Urinalysis culminates in a workload skew within the clinical microbiology laboratory. Routine processing involves screening via manual microscopy or…”
Get full text

Treatment of infections caused by multidrug-resistant Gram-negative bacteria: report of the British Society for Antimicrobial Chemotherapy/Healthcare Infection Society/British Infection Association Joint Working Party by Hawkey, Peter M, Warren, Roderic E, Livermore, David M, McNulty, Cliodna A M, Enoch, David A, Otter, Jonathan A, Wilson, A Peter R

“…The Working Party makes more than 100 tabulated recommendations in antimicrobial prescribing for the treatment of infections caused by multidrug-resistant…”
Get full text

Trichophyton rubrum-induced Majocchi's granuloma in an immunocompromised patient by Vetsiou, Evangelia, Maslin, Douglas, Enoch, David A, Ha, Thomas

Get full text

Exploring European Consensus About the Remaining Treatment Challenges and Subsequent Opportunities to Improve the Management of Invasive Fungal Infection (IFI) in the Intensive Care Unit by Hoenigl, Martin, Enoch, David A., Wichmann, Dominic, Wyncoll, Duncan, Cortegiani, Andrea

“…Background The global prevalence of invasive fungal infections (IFI) is increasing, particularly within Intensive Care Units (ICU), where Candida spp. and…”
Get full text

Fatal breakthrough mucormycosis in a multivisceral transplant patient receiving micafungin: Case report and literature review by Louis-Auguste, John R., Micallef, Christianne, Ambrose, Tim, Upponi, Sara, Butler, Andrew J., Massey, Dunecan, Middleton, Stephen J., Russell, Neil, Rutter, Charlotte S., Sharkey, Lisa M., Woodward, Jeremy, Gkrania-Klotsas, Effrossyni, Enoch, David A.

“…Antifungal agents are routinely used in the post-transplant setting for both prophylaxis and treatment of presumed and proven fungal infections. Micafungin is…”
Get full text

Economic impact of treating invasive mold disease with isavuconazole compared with liposomal amphotericin B in the UK by Bagshaw, Emma, Enoch, David A, Blackney, Michael, Posthumus, Jan, Kuessner, Daniel

“…Invasive mold diseases (IMDs) are associated with significant morbidity and mortality. Approved treatments include voriconazole (VORI), liposomal amphotericin…”
Get full text

Bacteremia in children: epidemiology, clinical diagnosis and antibiotic treatment by Pai, Sumita, Enoch, David A, Aliyu, Sani H

“…The diagnosis of bacteremia in children is important and it can be clinically challenging to recognize the signs and symptoms. The reported rates of bacteremia…”
Get more information

Pseudomonas aeruginosa bacteraemia in two UK district hospitals by Enoch, David A., Kuzhively, Julie, Sismey, Andrew, Grynik, Alina, Karas, Johannis Andreas

“…Pseudomonas aeruginosa bacteraemia is associated with significant morbidity and mortality. We retrospectively studied the epidemiology of bacteraemia due to P…”
Get full text

A positive BAL galactomannan in non-haemato-oncology patients risks harmful overtreatment by Martinelli, Anthony W, Patil, Parth, Wong, Vanessa K, Enoch, David A, Sander, Clare R

“… Evidence for the clinical utility of bronchoalveolar lavage (BAL) galactomannan in the management of fungal disease outside of haemato-oncology patients is…”
Get full text

National mycology laboratory diagnostic capacity for invasive fungal diseases in 2017: Evidence of sub-optimal practice by Schelenz, Silke, Owens, Katie, Guy, Rebecca, Rautemaa-Richardson, Riina, Manuel, Rohini J., Richardson, Malcolm, Moore, Caroline, Enoch, David A., Micallef, Christianne, Howard, Philip, Agrawal, Samir G., Johnson, Elizabeth M., Muller-Pebody, Berit

“…•There is a need to improve the UK diagnostic capacity for invasive fungal diseases.•A minority of laboratories have local access to β-glucan and galactomannan…”
Get full text