Search Results - "Eno, Colins O."

An Interaction between Bcl-xL and the Voltage-dependent Anion Channel (VDAC) Promotes Mitochondrial Ca2+ Uptake by Huang, Huiya, Hu, Xiangxin, Eno, Colins O., Zhao, Guoping, Li, Chi, White, Carl

“…The role of the antiapoptotic protein Bcl-xL in regulating mitochondrial Ca2+ ([Ca2+]mito) handling was examined in wild-type (WT) and Bcl-xL knock-out…”
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Activation of the Proapoptotic Bcl-2 Protein Bax by a Small Molecule Induces Tumor Cell Apoptosis by Zhao, Guoping, Zhu, Yanglong, Eno, Colins O., Liu, Yanlong, DeLeeuw, Lynn, Burlison, Joseph A., Chaires, Jonathan B., Trent, John O., Li, Chi

“…The proapoptotic Bcl-2 protein Bax by itself is sufficient to initiate apoptosis in almost all apoptotic paradigms. Thus, compounds that can facilitate…”
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ER stress modulates cellular metabolism by Wang, Xiaoli, Eno, Colins O, Altman, Brian J, Zhu, Yanglong, Zhao, Guoping, Olberding, Kristen E, Rathmell, Jeffrey C, Li, Chi

“…Changes in metabolic processes play a critical role in the survival or death of cells subjected to various stresses. In the present study, we have investigated…”
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The Bcl-2 proteins Noxa and Bcl-xL co-ordinately regulate oxidative stress-induced apoptosis by Eno, Colins O, Zhao, Guoping, Olberding, Kristen E, Li, Chi

“…Because the detailed molecular mechanisms by which oxidative stress induces apoptosis are not completely known, we investigated how the complex Bcl-2 protein…”
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Noxa couples lysosomal membrane permeabilization and apoptosis during oxidative stress by Eno, Colins O, Zhao, Guoping, Venkatanarayan, Avinashnarayan, Wang, Bing, Flores, Elsa R, Li, Chi

“…The exact roles of lysosomal membrane permeabilization (LMP) in oxidative stress-triggered apoptosis are not completely understood. Here, we first studied the…”
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Distinct roles of mitochondria- and ER-localized Bcl-xL in apoptosis resistance and Ca2+ homeostasis by Eno, Colins O, Eckenrode, Emily F, Olberding, Kristen E, Zhao, Guoping, White, Carl, Li, Chi

“…Bcl-2 proteins are major regulators of cellular responses to intrinsic and extrinsic apoptotic stimuli. Among them, overexpression of the antiapoptotic protein…”
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Distinct roles of mitochondria- and ER-localized Bcl-x L in apoptosis resistance and Ca 2+ homeostasis by Eno, Colins O., Eckenrode, Emily F., Olberding, Kristen E., Zhao, Guoping, White, Carl, Li, Chi

“…Bcl-2 proteins are major regulators of cellular responses to intrinsic and extrinsic apoptotic stimuli. Among them, overexpression of the antiapoptotic protein…”
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