Search Results - "Enns, Linda C"

Efficient discovery of DNA polymorphisms in natural populations by Ecotilling by Comai, Luca, Young, Kim, Till, Bradley J., Reynolds, Steven H., Greene, Elizabeth A., Codomo, Christine A., Enns, Linda C., Johnson, Jessica E., Burtner, Chris, Odden, Anthony R., Henikoff, Steven

“…Summary We have adapted the mutation detection technology used in Targeting Induced Local Lesions in Genomes (TILLING) to the discovery of polymorphisms in…”
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Spectrum of Chemically Induced Mutations From a Large-Scale Reverse-Genetic Screen in Arabidopsis by Greene, Elizabeth A, Codomo, Christine A, Taylor, Nicholas E, Henikoff, Jorja G, Till, Bradley J, Reynolds, Steven H, Enns, Linda C, Burtner, Chris, Johnson, Jessica E, Odden, Anthony R, Comai, Luca, Henikoff, Steven

“…Chemical mutagenesis has been the workhorse of traditional genetics, but it has not been possible to determine underlying rates or distributions of mutations…”
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Deficiency of the RIIβ subunit of PKA affects locomotor activity and energy homeostasis in distinct neuronal populations by Zheng, Ruimao, Yang, Linghai, Sikorski, Maria A, Enns, Linda C, Czyzyk, Traci A, Ladiges, Warren C, McKnight, G Stanley

“…Targeted disruption of RIIβ-protein kinase A (PKA) in mice leads to a lean phenotype, increased nocturnal locomotor activity, and activation of brown adipose…”
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Discovery of induced point mutations in maize genes by TILLING by Till, Bradley J, Reynolds, Steven H, Weil, Clifford, Springer, Nathan, Burtner, Chris, Young, Kim, Bowers, Elisabeth, Codomo, Christine A, Enns, Linda C, Odden, Anthony R, Greene, Elizabeth A, Comai, Luca, Henikoff, Steven

“…Going from a gene sequence to its function in the context of a whole organism requires a strategy for targeting mutations, referred to as reverse genetics…”
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Two callose synthases, GSL1 and GSL5, play an essential and redundant role in plant and pollen development and in fertility by Enns, Linda C, Kanaoka, Masahiro M, Torii, Keiko U, Comai, Luca, Okada, Kiyotaka, Cleland, Robert E

“…Callose, a beta-1,3-glucan that is widespread in plants, is synthesized by callose synthase. Arabidopsis thaliana contains a family of 12 putative callose…”
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Disruption of protein kinase A in mice enhances healthy aging by Enns, Linda C, Morton, John F, Treuting, Piper R, Emond, Mary J, Wolf, Norman S, Dai, Dao-Fu, McKnight, G S, Rabinovitch, Peter S, Ladiges, Warren C

“…Mutations that cause a reduction in protein kinase A (PKA) activity have been shown to extend lifespan in yeast. Loss of function of mammalian RIIbeta, a…”
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Mice lacking the Cβ subunit of PKA are resistant to angiotensin II-induced cardiac hypertrophy and dysfunction by Enns, Linda C, Bible, Kenneth L, Emond, Mary J, Ladiges, Warren C

“…PKA is a ubiquitous, multi-subunit cellular kinase that regulates a number of different physiological responses in response to cAMP, including metabolism, cell…”
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Correction: Disruption of Protein Kinase A in Mice Enhances Healthy Aging by Enns, Linda C., Morton, John F., Treuting, Piper R., Emond, Mary J., Wolf, Norman S., Dai, Dao-Fu, McKnight, G. S., Rabinovitch, Peter S., Ladiges, Warren C.

“…(2010) Correction: Disruption of Protein Kinase A in Mice Enhances Healthy Aging. No competing interests declared…”
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Protein kinase A signaling as an anti-aging target by Enns, Linda C, Ladiges, Warren

“…Abstract Protein kinase A (PKA) is a multi-unit protein kinase that mediates signal transduction of G-protein-coupled receptors through its activation by…”
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Large-scale discovery of induced point mutations with high-throughput TILLING by Till, Bradley J, Reynolds, Steven H, Greene, Elizabeth A, Codomo, Christine A, Enns, Linda C, Johnson, Jessica E, Burtner, Chris, Odden, Anthony R, Young, Kim, Taylor, Nicholas E, Henikoff, Jorja G, Comai, Luca, Henikoff, Steven

“…TILLING (Targeting Induced Local Lesions in Genomes) is a general reverse-genetic strategy that provides an allelic series of induced point mutations in genes…”
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Protein kinase A is a target for aging and the aging heart by Enns, Linda C, Pettan-Brewer, Christina, Ladiges, Warren

“…PKA is an important mediator of signal transduction downstream of G-protein-coupled receptors and plays a key role in the regulation of metabolism and…”
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Correction: Disruption of Protein Kinase A in Mice Enhances Healthy Aging by Enns, Linda C, Morton, John F, Treuting, Piper R, Emond, Mary J, Wolf, Norman S, Dao-Fu, Dai, McKnight, G S, Rabinovitch, Peter S, Ladiges, Warren C

“…Contributed reagents/materials/analysis tools: NSW GSM PSR WL. (2010) Correction: Disruption of Protein Kinase A in Mice Enhances Healthy Aging…”
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High-throughput TILLING for functional genomics by Till, Bradley J, Colbert, Trenton, Tompa, Rachel, Enns, Linda C, Codomo, Christine A, Johnson, Jessica E, Reynolds, Steven H, Henikoff, Jorja G, Greene, Elizabeth A, Steine, Michael N, Comai, Luca, Henikoff, Steven

“…Targeting-induced local lesions in genomes (TILLING) is a general strategy for identifying induced point mutations that can be applied to almost any organism…”
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Attenuation of Age-Related Metabolic Dysfunction in Mice With a Targeted Disruption of the Cβ Subunit of Protein Kinase A by Enns, Linda C., Morton, John F., Mangalindan, Ruby Sue, McKnight, G. Stanley, Schwartz, Michael W., Kaeberlein, Matt R., Kennedy, Brian K., Rabinovitch, Peter S., Ladiges, Warren C.

“…The cyclic adenosine monophosphate–dependent protein kinase A (PKA) pathway helps regulate both cell growth and division, and triglyceride storage and…”
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Deficiency of the RIIβ subunit of PKA affects locomotor activity and energy homeostasis in distinct neuronal populations by Zheng, Ruimao, Yang, Linghai, Sikorski, Maria A., Enns, Linda C., Czyzyk, Traci A., Ladiges, Warren C., McKnight, G. Stanley

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Deficiency of the RII[Beta] subunit of PKA affects locomotor activity and energy homeostasis in distinct neuronal populations by Zheng, Ruimao, Yang, Linghai, Sikorski, Maria A, Enns, Linda C, Czyzyk, Traci A, Ladiges, Warren C, McKnight, G Stanley

“…Targeted disruption of RIIβ-protein kinase A (PKA) in mice leads to a lean phenotype, increased nocturnal locomotor activity, and activation of brown adipose…”
Get full text

Attenuation of Age-Related Metabolic Dysfunction in Mice With a Targeted Disruption of the C  Subunit of Protein Kinase A by Enns, L. C., Morton, J. F., Mangalindan, R. S., McKnight, G. S., Schwartz, M. W., Kaeberlein, M. R., Kennedy, B. K., Rabinovitch, P. S., Ladiges, W. C.

“…The cyclic adenosine monophosphate - dependent protein kinase A (PKA) pathway helps regulate both cell growth and division, and triglyceride storage and…”
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Mice lacking the C[beta] subunit of PKA are resistant to angiotensin II-induced cardiac hypertrophy and dysfunction by Enns, Linda C, Bible, Kenneth L, Emond, Mary J, Ladiges, Warren C

“…Abstract Background: PKA is a ubiquitous, multi-subunit cellular kinase that regulates a number of different physiological responses in response to cAMP,…”
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Attenuation of age-related metabolic dysfunction in mice with a targeted disruption of the Cbeta subunit of protein kinase A by Enns, Linda C, Morton, John F, Mangalindan, Ruby Sue, McKnight, G Stanley, Schwartz, Michael W, Kaeberlein, Matt R, Kennedy, Brian K, Rabinovitch, Peter S, Ladiges, Warren C

“…The cyclic adenosine monophosphate-dependent protein kinase A (PKA) pathway helps regulate both cell growth and division, and triglyceride storage and…”
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Roles for callose in plant development and intercellular communication by Enns, Linda C

“…Cell-to-cell communication through plasmodesmata (PD) exists between most plant cells. The small fluorescent dye Lucifer Yellow CH (LYCH) has been used to…”
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