Search Results - "Engstrom, R G"

Solubilization, purification, and characterization of a truncated form of rat hepatic squalene synthetase by SHECHTER, I, KLINGER, E, RUCKER, M. L, ENGSTROM, R. G, SPIRITO, J. A, ISLAM, M. A, BOETTCHER, B. R, WEINSTEIN, D. B

“…Rat hepatic microsomal squalene synthetase (EC 2.5.1.21) was induced 25-fold by feeding rats with diet containing the hydroxymethylglutaryl-coenzyme A…”
Get full text

Hypolipidemic activity and toxicity studies of a styrl-hexahydroindolinol, 34-250 by Bagdon, R E, Engstrom, R G, Kelly, L A, Hartman, H A, Robison, R L, Visscher, G E

“…34-250 evoked hypocholesterolemic activity in the rat (14, 25, 31, 52, 112 mg/kg, po), dog (10, 20, 40 mg/kg, po), and monkey (30 mg/kg, po). Serum…”
Get more information

Occurrence and levels of 5-hydroxytryptamine in Schistosoma mansoni by Bennett, J, Bueding, E, Timms, A R, Engstrom, R G

Get more information

The Safety Evaluation of Fluvastatin, an HMG–CoA Reductase Inhibitor, in Beagle Dogs and Rhesus Monkeys by Hartman, Howard A., Myers, Laurie A., Evans, Morton, Robison, Rodney L., Engstrom, Robert G., Tse, Francis L.S.

“…Fluvastatin is a potent synthetic competitive inhibitor of β-hydroxy-β-methyl-glutaryl-coenzyme A (HMG–CoA) reductase, the rate-limiting enzyme in the…”
Get full text

Design and biological evaluation of a series of thiophene-based 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors by Coppola, Gary M., Damon, Robert E., Yu, Harvey, Engstrom, Robert G., Scallen, Terrence J.

“…A series of highly functionalized thiophene-based 3,5-dihydroxyheptenoic acid derivatives ( 10) were prepared from aldehydes 6 by homologation, aldol…”
Get full text

Expression, Purification, and Characterization of the Human Squalene Synthase: Use of Yeast and Baculoviral Systems by Soltis, D.A., Mcmahon, G., Caplan, S.L., Dudas, D.A., Chamberlin, H.A., Vattay, A., Dottavio, D., Rucker, M.L., Engstrom, R.G., Cornellkennon, S.A., Boettcher, B.R.

“…We have cloned and utilized a cDNA corresponding to the human squalene synthase gene to generate active enzyme from yeast and baculoviral expression systems…”
Get full text

The effects of 5-hydroxy-5(4'-chlorophenyl)-2, 3-dihydro-5H-imidazo (2, 1-a) isoindole (mazindol, SaH 42-548) on the metabolism of brain norepinephrine by Engstrom, R G, Kelly, L A, Gogerty, J H

“…Mazindol, 5-hydroxy-5-(4'-chlorophenyl)-i, 3-dihydro-5H-imidazo-(2, 1-a) isoindole, has demonstrated anorexic activity and other pharmacological responses…”
Get more information

Generalized phospholipidosis induced by an amphiphilic cationic psychotropic drug by Robison, R L, Visscher, G E, Roberts, S A, Engstrom, R G, Hartman, H A, Ballard, F H

“…Numerous amphiphilic cationic drugs cause generalized phospholipidosis in animals; one of these drugs is the Sandoz compound 200-125, a psychotropic agent…”
Get more information

In silico detection of sequence variations modifying transcriptional regulation by Andersen, Malin C, Engström, Pär G, Lithwick, Stuart, Arenillas, David, Eriksson, Per, Lenhard, Boris, Wasserman, Wyeth W, Odeberg, Jacob

“…Identification of functional genetic variation associated with increased susceptibility to complex diseases can elucidate genes and underlying biochemical…”
Get full text

Modification of Lofland's colorimetric semiautomated serum triglyceride determination, assessed by an enzymatic glycerol determination by Timms, A R, Kelly, L A, Spirito, J A, Engstrom, R G

“…Erroneously high values for serum triglyceride levels obtained with the semiautomated method of Lofland were found to be due to contamination of the…”
Get full text

Synthesis and biological evaluation of substituted 2,2'-oxybis(propionic acid) derivatives and related compounds by Bennett, Gregory B, Houlihan, William J, Mason, Robert B, Engstrom, Robert G

Get full text