Search Results - "Engman, M."

A novel homozygous pathogenic missense variant in COX6B1: Further delineation of the phenotype by Jennions, E., Olsson‐Engman, M., Visuttijai, K., Wiksell, Å., Fluriach Dominguez, N., Kollberg, G., Oldfors, A., Hedberg‐Oldfors, C.

“…Cytochrome c oxidase (COX) deficiency is a phenotypically diverse group of diseases caused by variants in over 30 genes. Biallelic pathogenic variants in…”
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Enhanced Efferocytosis of Apoptotic Cardiomyocytes Through Myeloid-Epithelial-Reproductive Tyrosine Kinase Links Acute Inflammation Resolution to Cardiac Repair After Infarction by Wan, Elaine, Yeap, Xin Yi, Dehn, Shirley, Terry, Rachael, Novak, Margaret, Zhang, Shuang, Iwata, Shinichi, Han, Xiaoqiang, Homma, Shunichi, Drosatos, Konstantinos, Lomasney, Jon, Engman, David M., Miller, Stephen D., Vaughan, Douglas E., Morrow, John P., Kishore, Raj, Thorp, Edward B.

“…RATIONALE:Efficient clearance of apoptotic cells (efferocytosis) is a prerequisite for inflammation resolution and tissue repair. After myocardial infarction,…”
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Molecular mechanisms of protein and lipid targeting to ciliary membranes by Emmer, Brian T, Maric, Danijela, Engman, David M

“…Cilia are specialized surface regions of eukaryotic cells that serve a variety of functions, ranging from motility to sensation and to regulation of cell…”
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Precision Health for Chagas Disease: Integrating Parasite and Host Factors to Predict Outcome of Infection and Response to Therapy by Martinez, Santiago J, Romano, Patricia S, Engman, David M

“…Chagas disease, caused by the infection with the protozoan parasite , is clinically manifested in approximately one-third of infected people by inflammatory…”
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Leishmaniasis and Chagas disease: Is there hope in nanotechnology to fight neglected tropical diseases? by Scariot, Debora B., Staneviciute, Austeja, Zhu, Jennifer, Li, Xiaomo, Scott, Evan A., Engman, David M.

“…Nanotechnology is revolutionizing many sectors of science, from food preservation to healthcare to energy applications. Since 1995, when the first…”
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Congenital cytomegalovirus infection: the impact of cerebral cortical malformations by Engman, M-L, Lewensohn-Fuchs, I, Mosskin, M, Malm, G

“…ABSTRACT Aim:  Cytomegalovirus has been suggested to have a teratogenous influence during the migration of neural cells from the ventricular zones to the…”
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Drug-induced hyperthermia with rhabdomyolysis in CLN3 disease by Savvidou, A., Jennions, E., Wikström, S., Olsson-Engman, M., Sofou, K., Darin, N.

“…CLN3 disease (MIM# 204200), the most prevalent of the neuronal ceroid lipofuscinoses (NCL), is an autosomal recessive disorder with juvenile onset…”
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TMPRSS2 activity may mediate sex differences in COVID-19 severity by Okwan-Duodu, Derick, Lim, Eun-Cheon, You, Sungyong, Engman, David M.

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Cytomegalovirus‐Specific CD4 and CD8 T Cell Responses in Infants and Children by Lidehäll, A. K., Engman, M.‐L., Sund, F., Malm, G., Lewensohn‐Fuchs, I., Ewald, U., Tötterman, T. H., Karltorp, E., Korsgren, O., Eriksson, B.‐M.

“…Congenital cytomegalovirus (CMV) infection is the most common congenital infection causing childhood morbidity. The pathogenetic mechanisms behind long‐term…”
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Sterol targeting drugs reveal life cycle stage-specific differences in trypanosome lipid rafts by Sharma, Aabha I., Olson, Cheryl L., Mamede, João I., Gazos-Lopes, Felipe, Epting, Conrad L., Almeida, Igor C., Engman, David M.

“…Cilia play important roles in cell signaling, facilitated by the unique lipid environment of a ciliary membrane containing high concentrations of sterol-rich…”
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Mifepristone for treatment of uterine leiomyoma. A prospective randomized placebo controlled trial by Engman, M., Granberg, S., Williams, A.R.W., Meng, C.X., Lalitkumar, P.G.L., Gemzell-Danielsson, K.

“…BACKGROUND Uterine leiomyomas are widely prevalent and frequently cause menorrhagia. The major therapeutic option today is hysterectomy. Medical options are of…”
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Trypanosoma cruzi GP63 Proteins Undergo Stage-Specific Differential Posttranslational Modification and Are Important for Host Cell Infection by Kulkarni, Manjusha M, Olson, Cheryl L, Engman, David M, McGwire, Bradford S

“…The protozoan Trypanosoma cruzi expresses multiple isoforms of the GP63 family of metalloproteases. Polyclonal antiserum against recombinant GP63 of T. cruzi…”
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Killing of African Trypanosomes by Antimicrobial Peptides by McGwire, Bradford S., Olson, Cheryl L., Tack, Brian F., Engman, David M.

“…Antimicrobial peptides are components of the innate immune systems of a wide variety of eukaryotic organisms and are being developed as antibiotics in the…”
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The life cycle of Trypanosoma cruzi revisited by TYLER, K. M, ENGMAN, D. M

“…The basic features of the life cycle of Trypanosoma cruzi have been known for nearly a century. Various aspects of the life cycle, however, have been…”
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Repurposing Carvedilol as a Novel Inhibitor of the Trypanosoma cruzi Autophagy Flux That Affects Parasite Replication and Survival by Rivero, Cynthia Vanesa, Martínez, Santiago José, Novick, Paul, Cueto, Juan Agustín, Salassa, Betiana Nebaí, Vanrell, María Cristina, Li, Xiaomo, Labriola, Carlos Alberto, Polo, Luis Mariano, Engman, David M., Clos, Joachim, Romano, Patricia Silvia

“…T. cruzi , the causal agent of Chagas disease, is a parasite able to infect different types of host cells and to persist chronically in the tissues of human…”
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Composition and sensory function of the trypanosome flagellar membrane by Maric, Danijela, Epting, Conrad L, Engman, David M

“…A cilium is an extension of the cell that contains an axonemal complex of microtubules and associated proteins bounded by a membrane which is contiguous with…”
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Identification of a palmitoyl acyltransferase required for protein sorting to the flagellar membrane by Emmer, Brian T, Souther, Christina, Toriello, Krista M, Olson, Cheryl L, Epting, Conrad L, Engman, David M

“…Protein palmitoylation has diverse effects in regulating protein membrane affinity, localization, binding partner interactions, turnover and function. Here, we…”
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The effect of mifepristone on breast cell proliferation in premenopausal women evaluated through fine needle aspiration cytology by Engman, M., Skoog, L., Söderqvist, G., Gemzell-Danielsson, K.

“…BACKGROUND Progestins as well as estrogens have a role in breast cell proliferation and the development of breast cancer. Here, the effect of mifepristone on…”
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Molecular Determinants of Ciliary Membrane Localization of Trypanosoma cruzi Flagellar Calcium-binding Protein by Maric, Danijela, McGwire, Bradford S., Buchanan, Kathryn T., Olson, Cheryl L., Emmer, Brian T., Epting, Conrad L., Engman, David M.

“…The flagellar calcium-binding protein (FCaBP) of Trypanosoma cruzi is localized to the flagellar membrane in all life cycle stages of the parasite…”
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Gene profiling for assessment of cell-based therapies by Engman, David M.

“…Comment on: Soares MBP, et al. Cell Cycle 2011; 10:1448-55…”
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