Search Results - "English, John C."

Epithelial tumor suppressor ELF3 is a lineage-specific amplified oncogene in lung adenocarcinoma by Enfield, Katey S. S., Marshall, Erin A., Anderson, Christine, Ng, Kevin W., Rahmati, Sara, Xu, Zhaolin, Fuller, Megan, Milne, Katy, Lu, Daniel, Shi, Rocky, Rowbotham, David A., Becker-Santos, Daiana D., Johnson, Fraser D., English, John C., MacAulay, Calum E., Lam, Stephen, Lockwood, William W., Chari, Raj, Karsan, Aly, Jurisica, Igor, Lam, Wan L.

“…Gene function in cancer is often cell type-specific. The epithelial cell-specific transcription factor ELF3 is a documented tumor suppressor in many epithelial…”
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Patient-Derived First Generation Xenografts of Non-Small Cell Lung Cancers: Promising Tools for Predicting Drug Responses for Personalized Chemotherapy by XIN DONG, JUN GUAN, LAM, Wan L, LASKIN, Janessa, LING, Victor, LAM, Stephen, YUZHUO WANG, ENGLISH, John C, FLINT, Julia, YEE, John, EVANS, Kenneth, MURRAY, Nevin, MACAULAY, Calum, NG, Raymond T, GOUT, Peter W

“…Current chemotherapeutic regimens have only modest benefit for non-small cell lung cancer (NSCLC) patients. Cumulative toxicities/drug resistance limit…”
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Patch testing in Lao medical students by Wootton, Catriona I, Soukavong, Mick, Kidoikhammouan, Sonexai, Samountry, Bounthome, English, John S C, Mayfong, Mayxay

“…Dermatological services in Laos, South East Asia are limited to the capital and patch testing is currently not available, so no data exists regarding the…”
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Correction: Patch testing in Lao medical students by Wootton, Catriona I, Soukavong, Mick, Kidoikhammouan, Sonexai, Samountry, Bounthome, English, John S. C, Mayxay, Mayfong

“…[This corrects the article DOI: 10.1371/journal.pone.0217192.]…”
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Correction: Patch test results in paediatric patients with atopic dermatitis in Laos by Wootton, Catriona I, Sodaly, Mong K, Billamay, Somxay X, English, John S. C, Mayxay, Mayfong

“…[This corrects the article DOI: 10.1371/journal.pone.0231455.]…”
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Lung adenocarcinoma of never smokers and smokers harbor differential regions of genetic alteration and exhibit different levels of genomic instability by Thu, Kelsie L, Vucic, Emily A, Chari, Raj, Zhang, Wei, Lockwood, William W, English, John C, Fu, Rong, Wang, Pei, Feng, Ziding, MacAulay, Calum E, Gazdar, Adi F, Lam, Stephen, Lam, Wan L

“…Recent evidence suggests that the observed clinical distinctions between lung tumors in smokers and never smokers (NS) extend beyond specific gene mutations,…”
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Confirmation of Recurrent Lung Cancer Following Resection Using Liquid Biopsy, a Proof-of-Concept Real-World Study by Naso, Julia R, Yip, Stephen, Hughesman, Curtis, Melosky, Barb, Dowhy, Tanner, McConechy, Melissa K, English, John C, Brasher, Penelope M A, Choi, James, Grant, Kyle, Yee, John, Lam, Stephen, McGuire, Anna

“…Appropriate management requires timely and accurate confirmation of non-small cell lung cancer (NSCLC) recurrence in patients who have had curative-intent…”
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Hyperspectral cell sociology reveals spatial tumor-immune cell interactions associated with lung cancer recurrence by Enfield, Katey S S, Martin, Spencer D, Marshall, Erin A, Kung, Sonia H Y, Gallagher, Paul, Milne, Katy, Chen, Zhaoyang, Nelson, Brad H, Lam, Stephen, English, John C, MacAulay, Calum E, Lam, Wan L, Guillaud, Martial

“…The tumor microenvironment (TME) is a complex mixture of tumor epithelium, stroma and immune cells, and the immune component of the TME is highly prognostic…”
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The Clinically Actionable Molecular Profile of Early versus Late-Stage Non-Small Cell Lung Cancer, an Individual Age and Sex Propensity-Matched Pair Analysis by McGuire, Anna L, McConechy, Melissa K, Melosky, Barb L, English, John C, Choi, James J, Peng, Defen, Yee, John, Furman, Benjamin L S, Aguirre Hernandez, Rosalia, Feijao, Pedro, Mulder, David, Hughesman, Curtis, Yip, Stephen

“…Background: Despite meticulous surgery for non-small cell lung cancer (NSCLC), relapse is as high as 70% at 5 years. Many institutions do not conduct reflexive…”
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Smoking status impacts microRNA mediated prognosis and lung adenocarcinoma biology by Vucic, Emily A, Thu, Kelsie L, Pikor, Larissa A, Enfield, Katey S S, Yee, John, English, John C, MacAulay, Calum E, Lam, Stephen, Jurisica, Igor, Lam, Wan L

“…Cigarette smoke is associated with the majority of lung cancers: however, 25% of lung cancer patients are non-smokers, and half of all newly diagnosed lung…”
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Integrative genomic analyses identify BRF2 as a novel lineage-specific oncogene in lung squamous cell carcinoma by Lockwood, William W, Chari, Raj, Coe, Bradley P, Thu, Kelsie L, Garnis, Cathie, Malloff, Chad A, Campbell, Jennifer, Williams, Ariane C, Hwang, Dorothy, Zhu, Chang-Qi, Buys, Timon P H, Yee, John, English, John C, Macaulay, Calum, Tsao, Ming-Sound, Gazdar, Adi F, Minna, John D, Lam, Stephen, Lam, Wan L

“…Traditionally, non-small cell lung cancer is treated as a single disease entity in terms of systemic therapy. Emerging evidence suggests the major…”
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Chronic Lung Allograft Dysfunction: Review of CT and Pathologic Findings by Byrne, Danielle, Nador, Roland G, English, John C, Yee, John, Levy, Robert, Bergeron, Celine, Swiston, John R, Mets, Onno M, Muller, Nestor L, Bilawich, Ana-Maria

“…Chronic lung allograft dysfunction (CLAD) is the most common cause of mortality in lung transplant recipients after the 1st year of transplantation. CLAD has…”
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Genetic disruption of KEAP1/CUL3 E3 ubiquitin ligase complex components is a key mechanism of NF-kappaB pathway activation in lung cancer by Thu, Kelsie L, Pikor, Larissa A, Chari, Raj, Wilson, Ian M, Macaulay, Calum E, English, John C, Tsao, Ming-Sound, Gazdar, Adi F, Lam, Stephen, Lam, Wan L, Lockwood, William W

“…Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (IKBKB) (IKK-β/IKK-2), which activates NF-κB, is a substrate of the KEAP1-CUL3-RBX1…”
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Metastatic Renal Cell Carcinoma to the Testis: A Clinicopathologic Analysis of Five Cases by Jones, Edward C., Yuan, Ren, So, Alan, Villamil, Carlos F., Zhou, Chen, Wang, Gang, English, John C.

“…The testicular spread of renal cell carcinoma is extremely rare. Five cases of renal cell carcinoma metastatic to the testis are described. The patients ranged…”
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Nucleotide-based therapies targeting clusterin chemosensitize human lung adenocarcinoma cells both in vitro and in vivo by July, Laura V, Beraldi, Eliana, So, Alan, Fazli, Ladan, Evans, Kenneth, English, John C, Gleave, Martin E

“…Introduction: Lung cancer is highly lethal and resistant to most anticancer interventions. Treatment resistance is mediated, in part, by enhanced expression of…”
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Recurrent pneumothorax related to diffuse dendriform pulmonary ossification in genetically predisposed individual by Tsai, Amy Po Yu, English, John C., Murphy, Darra, Sin, Don D.

“…Diffuse pulmonary ossification (DPO) is a rare disease with unknown pathogenesis, clinical manifestations, and treatment options. This report describes the…”
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The association between small airway obstruction and emphysema phenotypes in COPD by Kim, Won-Dong, Ling, Sean H, Coxson, Harvey O, English, John C, Yee, John, Levy, Robert D, Paré, Peter D, Hogg, James C

“…Airflow limitation in COPD is due to a variable combination of small airway obstruction and centrilobular emphysema (CLE) and/or panlobular emphysema (PLE),…”
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Contact sensitivity to preservatives in the UK, 2004-2005: results of multicentre study by Jong, Cherng T., Statham, Barry N., Green, Cathy M., King, Codagh M., Gawkrodger, David J., Sansom, Jane E., English, John S. C., Wilkinson, S. Mark, Ormerod, Anthony D., Chowdhury, Mahbub M. U.

“…Preservative sensitivity in the UK was last assessed in 2000. Given the changes in preservative usage, we have re‐evaluated our patch test data in order to…”
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Lessons from lung transplantation: Cause for redefining the pathophysiology of pulmonary hypertension in gaucher disease by Goobie, Gillian C., Sirrs, Sandra M., Yee, John, English, John C., Bergeron, Celine, Nador, Roland, Swiston, John R., Mistry, Pramod K., Paquin, Wendy, Levy, Robert D.

“…Gaucher disease type 1 (GD1) is a lysosomal storage disease rarely resulting in end stage pulmonary hypertension (PH) and interstitial lung disease. There have…”
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Quantification of lung surface area using computed tomography by Yuan, Ren, Nagao, Taishi, Paré, Peter D, Hogg, James C, Sin, Don D, Elliott, Mark W, Loy, Leanna, Xing, Li, Kalloger, Steven E, English, John C, Mayo, John R, Coxson, Harvey O

“…To refine the CT prediction of emphysema by comparing histology and CT for specific regions of lung. To incorporate both regional lung density measured by CT…”
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