Search Results - "English, Jane"
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Microbiota from Alzheimer's patients induce deficits in cognition and hippocampal neurogenesis
Published in Brain (London, England : 1878) (01-12-2023)“…Alzheimer's disease is a complex neurodegenerative disorder leading to a decline in cognitive function and mental health. Recent research has positioned the…”
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Effect of L-Ergothioneine on the metabolic plasma profile of the RUPP rat model of pre-eclampsia
Published in PloS one (31-03-2020)“…Pre-eclampsia is a major cause of maternal and fetal mortality and morbidity worldwide. Its pathophysiology remains unclear, but mitochondrial dysfunction and…”
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3
The 'middle-aging' brain
Published in Trends in neurosciences (Regular ed.) (01-04-2024)“…Middle age (roughly the fifth and sixth decades of human life) has historically been understudied compared to more advanced age, but is emerging as marking a…”
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The Neuroproteomics of Schizophrenia
Published in Biological psychiatry (1969) (15-01-2011)“…Proteomics is the study of global gene expression of an organ, body system, fluid, or cellular compartment at the protein level. Proteomic findings are…”
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Plasma proteomic signature of chronic psychosocial stress in mice
Published in Physiology & behavior (10-11-2024)“…•Abundances of 38 plasma proteins were affected by chronic psychosocial stress in mice.•The proteins function in inflammatory & immune response, complement &…”
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Evaluation of hydrophilic interaction chromatography versus reversed-phase chromatography for fast aqueous species distribution analysis of Nickel(II)-Histidine complex species
Published in Journal of Chromatography A (29-03-2023)“…•HILIC can be appropriate for investigating coordination metal complexes since these metals are generally charged and highly polar.•The metal complex…”
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Blood-Based Protein Changes in Childhood Are Associated With Increased Risk for Later Psychotic Disorder: Evidence From a Nested Case-Control Study of the ALSPAC Longitudinal Birth Cohort
Published in Schizophrenia bulletin (15-02-2018)“…The identification of early biological changes associated with the psychotic disorder (PD) is important as it may provide clues to the underlying…”
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2-D DIGE analysis implicates cytoskeletal abnormalities in psychiatric disease
Published in Proteomics (Weinheim) (01-06-2009)“…The mechanisms underlying white matter changes in psychiatric disease are not known. We aimed to characterise the differential protein expression in deep white…”
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Exercise mitigates a gut microbiota-mediated reduction in adult hippocampal neurogenesis and associated behaviours in rats
Published in Translational psychiatry (24-04-2024)“…Lifestyle factors, especially exercise, impact the manifestation and progression of psychiatric and neurodegenerative disorders such as depression and…”
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Integrated Lipidomics and Proteomics Point to Early Blood-Based Changes in Childhood Preceding Later Development of Psychotic Experiences: Evidence From the Avon Longitudinal Study of Parents and Children
Published in Biological psychiatry (1969) (01-07-2019)“…The identification of early biomarkers of psychotic experiences (PEs) is of interest because early diagnosis and treatment of those at risk of future disorder…”
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11
Proteolysis during tumor cell extravasation in vitro: metalloproteinase involvement across tumor cell types
Published in PloS one (23-10-2013)“…To test if proteolysis is involved in tumor cell extravasation, we developed an in vitro model where tumor cells cross an endothelial monolayer cultured on a…”
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Association between phospholipid metabolism in plasma and spontaneous preterm birth: a discovery lipidomic analysis in the cork pregnancy cohort
Published in Metabolomics (24-01-2020)“…Introduction Preterm birth (PTB) is defined as birth occurring before 37 weeks’ gestation, affects 5–9% of all pregnancies in developed countries, and is the…”
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Blood biomarker discovery in drug-free schizophrenia: the contributionof proteomics and multiplex immunoassays
Published in Expert review of proteomics (01-12-2016)“…Recent evidence supports an association between systemic abnormalities and the pathology of psychotic disorders which has led to the search for peripheral…”
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14
Proteomic analysis investigating kidney transplantation outcomes- a scoping review
Published in BMC nephrology (22-11-2023)“…Kidney transplantation is the optimal treatment option for most patients with end-stage kidney disease given the significantly lower morbidity and mortality…”
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Dysregulation of miRNA-9 in a Subset of Schizophrenia Patient-Derived Neural Progenitor Cells
Published in Cell reports (Cambridge) (03-05-2016)“…Converging evidence indicates that microRNAs (miRNAs) may contribute to disease risk for schizophrenia (SZ). We show that microRNA-9 (miR-9) is abundantly…”
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Anxiety, depression, and stress in response to the coronavirus disease-19 pandemic
Published in Cirugia y cirujanos (2020)“…The objective of the study was to determine the state of anxiety, depression, and stress present in the society during the development of the 2019 coronavirus…”
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ApoE elevation is associated with the persistence of psychotic experiences from age 12 to age 18: Evidence from the ALSPAC birth cohort
Published in Schizophrenia research (01-07-2019)“…Apolipoproteins, which play important roles in lipid metabolism, innate immunity and synaptic signalling, have been implicated in first episode psychosis and…”
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Student teamwork in professional programmes in higher education: a comparative study of Spain and South Africa
Published in Journal of teaching and learning for graduate employability (20-11-2022)“…Teamwork is a fundamental employability skill and, as such, is fostered in professional programmes. This study presents a comparative analysis of higher…”
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Targeted Proteomics for Validation of Biomarkers in Early Psychosis
Published in Biological psychiatry (1969) (15-09-2014)Get full text
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Partitioning the proteome: phase separation for targeted analysis of membrane proteins in human post-mortem brain
Published in PloS one (22-06-2012)“…Neuroproteomics is a powerful platform for targeted and hypothesis driven research, providing comprehensive insights into cellular and sub-cellular disease…”
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