Search Results - "Englert, Neal A."

Distinct Epigenetic Effects of Tobacco Smoking in Whole Blood and among Leukocyte Subtypes by Su, Dan, Wang, Xuting, Campbell, Michelle R, Porter, Devin K, Pittman, Gary S, Bennett, Brian D, Wan, Ma, Englert, Neal A, Crowl, Christopher L, Gimple, Ryan N, Adamski, Kelly N, Huang, Zhiqing, Murphy, Susan K, Bell, Douglas A

“…Tobacco smoke exposure dramatically alters DNA methylation in blood cells and may mediate smoking-associated complex diseases through effects on immune cell…”
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Identification of Smoking-Associated Differentially Methylated Regions Using Reduced Representation Bisulfite Sequencing and Cell type-Specific Enhancer Activation and Gene Expression by Wan, Ma, Bennett, Brian D, Pittman, Gary S, Campbell, Michelle R, Reynolds, Lindsay M, Porter, Devin K, Crowl, Christopher L, Wang, Xuting, Su, Dan, Englert, Neal A, Thompson, Isabel J, Liu, Yongmei, Bell, Douglas A

“…Cigarette smoke is a causal factor in cancers and cardiovascular disease. Smoking-associated differentially methylated regions (SM-DMRs) have been observed in…”
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Genetic and epigenetic regulation of AHR gene expression in MCF-7 breast cancer cells: Role of the proximal promoter GC-rich region by Englert, Neal A., Turesky, Robert J., Han, Weiguo, Bessette, Erin E., Spivack, Simon D., Caggana, Michele, Spink, David C., Spink, Barbara C.

“…The aryl hydrocarbon receptor (AhR), a ligand-activated transcription factor, contributes to carcinogenesis through its role in the regulation of cytochrome…”
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Correction: Distinct Epigenetic Effects of Tobacco Smoking in Whole Blood and among Leukocyte Subtypes by Su, Dan, Wang, Xuting, Campbell, Michelle R, Porter, Devin K, Pittman, Gary S, Bennett, Brian D, Wan, Ma, Englert, Neal A, Crowl, Christopher L, Gimple, Ryan C, Adamski, Kelly N, Huang, Zhiqing, Murphy, Susan K, Bell, Douglas A

“…[This corrects the article DOI: 10.1371/journal.pone.0166486.]…”
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Pregnane X receptor (PXR) deficiency improves high fat diet-induced obesity via induction of fibroblast growth factor 15 (FGF15) expression by Zhao, Li-Yang, Xu, Jia-Yi, Shi, Zhe, Englert, Neal A., Zhang, Shu-Yun

“…[Display omitted] Obesity has become a significant global health problem, and is a high risk factor for a variety of metabolic diseases. Fibroblast growth…”
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Epigenetic modification of histone 3 lysine 27: mediator subunit MED25 is required for the dissociation of polycomb repressive complex 2 from the promoter of cytochrome P450 2C9 by Englert, Neal A, Luo, George, Goldstein, Joyce A, Surapureddi, Sailesh

“…The Mediator complex is vital for the transcriptional regulation of eukaryotic genes. Mediator binds to nuclear receptors at target response elements and…”
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Pyrene is a Novel Constitutive Androstane Receptor (CAR) Activator and Causes Hepatotoxicity by CAR by Zhang, Xiao-Jie, Shi, Zhe, Lyv, Jing-Xi, He, Xuyan, Englert, Neal A, Zhang, Shu-Yun

“…Polycyclic aromatic hydrocarbons (PAHs) are a class of ubiquitous persistent environmental pollutants which are primarily formed from the incomplete combustion…”
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Upregulation of human CYP2C9 expression by Bisphenol A via estrogen receptor alpha (ERα) and Med25 by Xu, Jia‐Yi, Wu, Liang, Shi, Zhe, Zhang, Xiao‐Jie, Englert, Neal A., Zhang, Shu‐Yun

“…ABSTRACT Bisphenol A (BPA) is an important industrial chemical, mainly used in the manufacture of polycarbonate plastic and epoxy resins. Due to its widespread…”
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Persistent and non-persistent changes in gene expression result from long-term estrogen exposure of MCF-7 breast cancer cells by Englert, Neal A., Spink, Barbara C., Spink, David C.

“…▶ Long-term estrogen exposure in MCF-7 cells causes a persistent up-regulation of the AhR. ▶ Numerous genes up-regulated by long-term estrogen are insensitive…”
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Long-term estrogen exposure promotes carcinogen bioactivation, induces persistent changes in gene expression, and enhances the tumorigenicity of MCF-7 human breast cancer cells by Spink, Barbara C., Bennett, James A., Pentecost, Brian T., Lostritto, Nicole, Englert, Neal A., Benn, Geoffrey K., Goodenough, Angela K., Turesky, Robert J., Spink, David C.

“…The cumulative exposure to estrogens is an important determinant in the risk of breast cancer, yet the full range of mechanisms involving estrogens in the…”
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Epigenetic Modification of Histone 3 Lysine 27 by Englert, Neal A., Luo, George, Goldstein, Joyce A., Surapureddi, Sailesh

“…The Mediator complex is vital for the transcriptional regulation of eukaryotic genes. Mediator binds to nuclear receptors at target response elements and…”
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Upregulation of human CYP2C9 expression by Bisphenol A via estrogen receptor alpha (ERα) and Med25: BPA Upregulates Human CYP2C9 Expression Through ERα and Med25 by Xu, Jia-Yi, Wu, Liang, Shi, Zhe, Zhang, Xiao-Jie, Englert, Neal A., Zhang, Shu-Yun

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Regulation of the aryl hydrocarbon receptor and the signal transducer and activator of transcription 1 by long-term estrogen exposure in breast carcinoma cells by Englert, Neal A

“…The risk of developing breast cancer is known to be associated with a woman’s lifetime exposure to estrogens, both endogenous and exogenous. Increased exposure…”
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Regulation of the aryl hydrocarbon receptor and the signal transducer and activator of transcription 1 by long-term estrogen exposure in breast carcinoma cells by Englert, Neal A

“…The risk of developing breast cancer is known to be associated with a woman's lifetime exposure to estrogens, both endogenous and exogenous. Increased exposure…”
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