Search Results - "Englaender, Jacob"

Stabilizing Leaf and Branch Compost Cutinase (LCC) with Glycosylation: Mechanism and Effect on PET Hydrolysis by Shirke, Abhijit N, White, Christine, Englaender, Jacob A, Zwarycz, Allison, Butterfoss, Glenn L, Linhardt, Robert J, Gross, Richard A

“…Cutinases are polyester hydrolases that show a remarkable capability to hydrolyze polyethylene terephthalate (PET) to its monomeric units. This revelation has…”
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Masquerading microbial pathogens: capsular polysaccharides mimic host-tissue molecules by Cress, Brady F., Englaender, Jacob A., He, Wenqin, Kasper, Dennis, Linhardt, Robert J., Koffas, Mattheos A.G.

“…Abstract The increasing prevalence of antibiotic-resistant bacteria portends an impending postantibiotic age, characterized by diminishing efficacy of common…”
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Complete Biosynthesis of Anthocyanins Using E. coli Polycultures by Jones, J Andrew, Vernacchio, Victoria R, Collins, Shannon M, Shirke, Abhijit N, Xiu, Yu, Englaender, Jacob A, Cress, Brady F, McCutcheon, Catherine C, Linhardt, Robert J, Gross, Richard A, Koffas, Mattheos A G

“…Fermentation-based chemical production strategies provide a feasible route for the rapid, safe, and sustainable production of a wide variety of important…”
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Hydrolysis of lignocellulose by anaerobic fungi produces free sugars and organic acids for two‐stage fine chemical production with Kluyveromyces marxianus by Hillman, Ethan T., Li, Mengwan, Hooker, Casey A., Englaender, Jacob A., Wheeldon, Ian, Solomon, Kevin V.

“…Development of the bioeconomy is driven by our ability to access the energy‐rich carbon trapped in recalcitrant plant materials. Current strategies to release…”
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Rapid generation of CRISPR/dCas9-regulated, orthogonally repressible hybrid T7-lac promoters for modular, tuneable control of metabolic pathway fluxes in Escherichia coli by Cress, Brady F, Jones, J Andrew, Kim, Daniel C, Leitz, Quentin D, Englaender, Jacob A, Collins, Shannon M, Linhardt, Robert J, Koffas, Mattheos A G

“…Robust gene circuit construction requires use of promoters exhibiting low crosstalk. Orthogonal promoters have been engineered utilizing an assortment of…”
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CRISPathBrick: Modular Combinatorial Assembly of Type II‑A CRISPR Arrays for dCas9-Mediated Multiplex Transcriptional Repression in E. coli by Cress, Brady F, Toparlak, Ö. Duhan, Guleria, Sanjay, Lebovich, Matthew, Stieglitz, Jessica T, Englaender, Jacob A, Jones, J. Andrew, Linhardt, Robert J, Koffas, Mattheos A. G

“…Programmable control over an addressable global regulator would enable simultaneous repression of multiple genes and would have tremendous impact on the field…”
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Effect of Genomic Integration Location on Heterologous Protein Expression and Metabolic Engineering in E. coli by Englaender, Jacob A, Jones, J. Andrew, Cress, Brady F, Kuhlman, Thomas E, Linhardt, Robert J, Koffas, Mattheos A. G

“…Chromosomal integration offers a selection-free alternative to DNA plasmids for expression of foreign proteins and metabolic pathways. Episomal plasmid DNA is…”
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Minicell‐based fungal RNAi delivery for sustainable crop protection by Islam, Md Tabibul, Davis, Zachery, Chen, Lisa, Englaender, Jacob, Zomorodi, Sepehr, Frank, Joseph, Bartlett, Kira, Somers, Elisabeth, Carballo, Sergio M., Kester, Mark, Shakeel, Ameer, Pourtaheri, Payam, Sherif, Sherif M.

“…Spray‐induced gene silencing (SIGS) using topical dsRNA applications has risen as a promising, target‐specific, and environmentally‐friendly disease management…”
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Expression and secretion of glycosylated heparin biosynthetic enzymes using Komagataella pastoris by Englaender, Jacob A., Zhu, Yuanyuan, Shirke, Abhijit N., Lin, Lei, Liu, Xinyue, Zhang, Fuming, Gross, Richard A., Koffas, Mattheos A. G., Linhardt, Robert J.

“…Heparin, an anticoagulant drug, is biosynthesized in selected animal cells. The heparin biosynthetic enzymes mainly consist of sulfotransferases and all are…”
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Anaerobic Fungal Mevalonate Pathway Genomic Biases Lead to Heterologous Toxicity Underpredicted by Codon Adaptation Indices by Hillman, Ethan T., Frazier, Elizabeth M., Shank, Evan K., Ortiz-Velez, Adrian N., Englaender, Jacob A., Solomon, Kevin V.

“…Anaerobic fungi are emerging biotechnology platforms with genomes rich in biosynthetic potential. Yet, the heterologous expression of their biosynthetic…”
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Expression of Low Endotoxin 3-O-Sulfotransferase in Bacillus subtilis and Bacillus megaterium by Wang, Wenya, Englaender, Jacob A., Xu, Peng, Mehta, Krunal K., Suwan, Jiraporn, Dordick, Jonathan S., Zhang, Fuming, Yuan, Qipeng, Linhardt, Robert J., Koffas, Mattheos

“…A key enzyme for the biosynthesis and bioengineering of heparin, 3- O -sulfotransferase-1 (3-OST-1), was expressed and purified in Gram-positive Bacillus…”
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Hydrolysis of lignocellulose by anaerobic fungi produces free sugars and organic acids for two-stage fine chemical production with Kluyveromyces marxianus by Hillman, Ethan T., Li, Mengwan, Hooker, Casey A., Englaender, Jacob A., Wheeldon, Ian, Solomon, Kevin V.

“…Not provided…”
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Hydrolysis of lignocellulose by anaerobic fungi produces free sugars and organic acids for two–stage fine chemical production with Kluyveromyces marxianus by Hillman, Ethan T., Li, Mengwan, Hooker, Casey A., Englaender, Jacob A., Wheeldon, Ian, Solomon, Kevin V.

“…AbstractDevelopment of the bioeconomy is driven by our ability to access the energy‐rich carbon trapped in recalcitrant plant materials. Current strategies to…”
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Exploring Alternative Expression Systems for Expression of Heterologous Proteins and Metabolic Pathways by Englaender, Jacob Alexander

“…Heparin is the most widely used anticoagulant drug in the world. Current production of heparin from porchine intestinal tissue led to a contamination of the…”
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Complete Biosynthesis of Anthocyanins Using italic toggle="yes">E. coli /italic> Polycultures by J. Andrew Jones, Victoria R. Vernacchio, Shannon M. Collins, Abhijit N. Shirke, Yu Xiu, Jacob A. Englaender, Brady F. Cress, Catherine C. McCutcheon, Robert J. Linhardt, Richard A. Gross, Mattheos A. G. Koffas

“…ABSTRACT Fermentation-based chemical production strategies provide a feasible route for the rapid, safe, and sustainable production of a wide variety of…”
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