Search Results - "Engesæter, Birgit Ø."

Aldehyde dehydrogenase (ALDH) activity does not select for cells with enhanced aggressive properties in malignant melanoma by Prasmickaite, Lina, Engesaeter, Birgit Ø, Skrbo, Nirma, Hellenes, Tina, Kristian, Alexandr, Oliver, Nina K, Suo, Zhenhe, Maelandsmo, Gunhild M

“…Malignant melanoma is an exceptionally aggressive, drug-resistant and heterogeneous cancer. Recently it has been shown that melanoma cells with high clonogenic…”
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PCI-enhanced adenoviral transduction employs the known uptake mechanism of adenoviral particles by Engesaeter, Birgit Ø, Bonsted, Anette, Berg, Kristian, Høgset, Anders, Engebråten, Olav, Fodstad, Øystein, Curiel, David T, Maelandsmo, Gunhild M

“…The development of methods for efficient and specific delivery of therapeutic genes into target tissues is an important issue for further development of in…”
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Fibroblast-induced switching to the mesenchymal-like phenotype and PI3K/mTOR signaling protects melanoma cells from BRAF inhibitors by Seip, Kotryna, Fleten, Karianne G, Barkovskaya, Anna, Nygaard, Vigdis, Haugen, Mads H, Engesæter, Birgit Ø, Mælandsmo, Gunhild M, Prasmickaite, Lina

“…The knowledge on how tumor-associated stroma influences efficacy of anti-cancer therapy just started to emerge. Here we show that lung fibroblasts reduce…”
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Photochemical internalisation in drug and gene delivery by Høgset, Anders, Prasmickaite, Lina, Selbo, Pål K, Hellum, Marit, Engesæter, Birgit Ø, Bonsted, Anette, Berg, Kristian

“…This article reviews a novel technology, named photochemical internalisation (PCI), for light-induced delivery of genes, proteins and many other classes of…”
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Photochemical internalization: a new tool for drug delivery by Berg, Kristian, Folini, Marco, Prasmickaite, Lina, Selbo, Pål Kristian, Bonsted, Anette, Engesaeter, Birgit Ø, Zaffaroni, Nadia, Weyergang, Anette, Dietze, Andreas, Maelandsmo, Gunhild M, Wagner, Ernst, Norum, Ole-Jacob, Høgset, Anders

“…The utilisation of macromolecules in the therapy of cancer and other diseases is becoming increasingly important. Recent advances in molecular biology and…”
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Targeting inhibitor of apoptosis proteins in combination with dacarbazine or TRAIL in melanoma cells by Engesæter, Birgit Ø., Sathermugathevan, Menaka, Hellenes, Tina, Engebråten, Olav, Holm, Ruth, Flørenes, Vivi Ann, Mælandsmo, Gunhild M.

“…Melanoma is a highly aggressive malignant tumor with an exceptional ability to develop resistance and no curative therapy is available for patients with…”
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Photochemical treatment with endosomally localized photosensitizers enhances the number of adenoviruses in the nucleus by Engesæter, Birgit Ø., Tveito, Siri, Bonsted, Anette, Engebraaten, Olav, Berg, Kristian, Mælandsmo, Gunhild M.

“…Background In the present study the physical targeting technique photochemical internalization (PCI) has been used in combination with adenovirus. We have…”
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Aldehyde Dehydrogenase by Prasmickaite, Lina, Engesæter, Birgit Ø, Skrbo, Nirma, Hellenes, Tina, Kristian, Alexandr, Oliver, Nina K, Suo, Zhenhe, Mælandsmo, Gunhild M

“…Background Malignant melanoma is an exceptionally aggressive, drug-resistant and heterogeneous cancer. Recently it has been shown that melanoma cells with high…”
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Photochemically enhanced gene delivery with cationic lipid formulations by Hellum, Marit, Høgset, Anders, Engesaeter, Birgit O, Prasmickaite, Lina, Stokke, Trond, Wheeler, Carl, Berg, Kristian

“…Entrapment and degradation of transfecting DNA in endocytic vesicles often hampers the use of lipidic vectors for gene delivery purposes. Photochemical…”
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Combined treatment with Ad-hTRAIL and DTIC or SAHA is associated with increased mitochondrial-mediated apoptosis in human melanoma cell lines by Lillehammer, Trine, Engesaeter, Birgit O., Prasmickaite, Lina, Maelandsmo, Gunhild M., Fodstad, Oystein, Engebraaten, Olav

“…Background Currently, dacarbazine (DTIC) is the only approved systemic treatment for metastatic malignant melanoma. However, the modest treatment effect…”
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Light-directed gene delivery by photochemical internalisation by Prasmickaite, Lina, Høgset, Anders, Engesaeter B, Birgit Ø, Bonsted, Anette, Berg, Kristian

“…This article reviews a novel technology, named photochemical internalisation (PCI), for light-directed delivery of transgenes. Most gene therapy vectors are…”
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Photochemically mediated delivery of AdhCMV-TRAIL augments the TRAIL-induced apoptosis in colorectal cancer cell lines by Engesaeter, Birgit, Bonsted, Anette, Lillehammer, Trine, Engebraaten, Olav, Berg, Kristian, Maelandsmo, Gunhild

“…Tumor targeting is an important issue in cancer gene therapy. We have developed a light-specific transduction method, named photochemical internalization…”
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Melanoma-specific expression in first-generation adenoviral vectors in vitro and in vivo -- use of the human tyrosinase promoter with human enhancers by Lillehammer, Trine, Tveito, Siri, Engesaeter, Birgit O, Fodstad, Oystein, Maelandsmo, Gunhild M, Engebraaten, Olav

“…Current treatment regimens for patients with metastatic melanoma are not curative, and new treatment strategies are needed. One possible approach is targeted…”
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Photochemical transfection: a technology for efficient light-directed gene delivery by Høgset, Anders, Prasmickaite, Lina, Hellum, Marit, Engesaeter, Birgit O, Olsen, Vibeke M, Tjelle, Torunn E, Wheeler, Carl J, Berg, Kristian

“…Most synthetic gene delivery vectors are taken up in the cell by endocytosis, and inefficient escape of the transgene from endocytic vesicles often is a major…”
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