Search Results - "Engels, Ina"

A new antibiotic kills pathogens without detectable resistance by Ling, Losee L., Schneider, Tanja, Peoples, Aaron J., Spoering, Amy L., Engels, Ina, Conlon, Brian P., Mueller, Anna, Schäberle, Till F., Hughes, Dallas E., Epstein, Slava, Jones, Michael, Lazarides, Linos, Steadman, Victoria A., Cohen, Douglas R., Felix, Cintia R., Fetterman, K. Ashley, Millett, William P., Nitti, Anthony G., Zullo, Ashley M., Chen, Chao, Lewis, Kim

“…Antibiotic resistance is spreading faster than the introduction of new compounds into clinical practice, causing a public health crisis. Most antibiotics were…”
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Lipid Requirements for the Enzymatic Activity of MraY Translocases and in Vitro Reconstitution of the Lipid II Synthesis Pathway by Henrich, Erik, Ma, Yi, Engels, Ina, Münch, Daniela, Otten, Christian, Schneider, Tanja, Henrichfreise, Beate, Sahl, Hans-Georg, Dötsch, Volker, Bernhard, Frank

“…Screening of new compounds directed against key protein targets must continually keep pace with emerging antibiotic resistances. Although periplasmic enzymes…”
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Dual Targeting of Cell Wall Precursors by Teixobactin Leads to Cell Lysis by Homma, Tomoyuki, Nuxoll, Austin, Gandt, Autumn Brown, Ebner, Patrick, Engels, Ina, Schneider, Tanja, Götz, Friedrich, Lewis, Kim, Conlon, Brian P

“…Teixobactin represents the first member of a newly discovered class of antibiotics that act through inhibition of cell wall synthesis. Teixobactin binds…”
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The cell wall precursor lipid II acts as a molecular signal for the Ser/Thr kinase PknB of Staphylococcus aureus by Hardt, Patrick, Engels, Ina, Rausch, Marvin, Gajdiss, Mike, Ulm, Hannah, Sass, Peter, Ohlsen, Knut, Sahl, Hans-Georg, Bierbaum, Gabriele, Schneider, Tanja, Grein, Fabian

“…Abstract The assembly of the bacterial cell wall requires synchronization of a multitude of biosynthetic machineries and regulatory networks. The…”
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Structural variations of the cell wall precursor lipid II and their influence on binding and activity of the lipoglycopeptide antibiotic oritavancin by Münch, Daniela, Engels, Ina, Müller, Anna, Reder-Christ, Katrin, Falkenstein-Paul, Hildegard, Bierbaum, Gabriele, Grein, Fabian, Bendas, Gerd, Sahl, Hans-Georg, Schneider, Tanja

“…Oritavancin is a semisynthetic derivative of the glycopeptide antibiotic chloroeremomycin with activity against Gram-positive pathogens, including…”
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Erratum: A new antibiotic kills pathogens without detectable resistance by Ling, Losee L., Schneider, Tanja, Peoples, Aaron J., Spoering, Amy L., Engels, Ina, Conlon, Brian P., Mueller, Anna, Schäberle, Till F., Hughes, Dallas E., Epstein, Slava, Jones, Michael, Lazarides, Linos, Steadman, Victoria A., Cohen, Douglas R., Felix, Cintia R., Fetterman, K. Ashley, Millett, William P., Nitti, Anthony G., Zullo, Ashley M., Chen, Chao, Lewis, Kim

“…Nature 517, 455–459 (2015); doi:10.1038/nature14098 In Fig. 3d of this Article, the ‘2:1’ and ‘1:1’ labels at the bottom of the panel were inadvertently…”
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