Search Results - "Engelmann, Afra"
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Hyperproliferation, cancer, and inflammation in mice expressing a Δ133p53-like isoform
Published in Blood (12-05-2011)“…The p53 protein is a pivotal tumor suppressor that is frequently mutated in many human cancers, although precisely how p53 prevents tumors is still unclear. To…”
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Homing and invasiveness of MLL/ENL leukemic cells is regulated by MEF2C
Published in Blood (17-09-2009)“…Acute myelogenous leukemia is driven by leukemic stem cells (LSCs) generated by mutations that confer (or maintain) self-renewal potential coupled to an…”
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A Novel Archaeal Transcriptional Regulator of Heat Shock Response
Published in The Journal of biological chemistry (03-01-2003)“…Archaea have a eukaryotic type of transcriptional machinery containing homologues of the transcription factors TATA-binding protein (TBP) and TFIIB (TFB) and a…”
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TrmB, a Sugar-specific Transcriptional Regulator of the Trehalose/Maltose ABC Transporter from the Hyperthermophilic Archaeon Thermococcus litoralis
Published in The Journal of biological chemistry (10-01-2003)“…We report the characterization of TrmB, a protein of 38,800 apparent molecular weight, that is involved in the maltose-specific regulation of a gene cluster in…”
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Importance of Receptor Usage, Fli1 Activation, and Mouse Strain for the Stem Cell Specificity of 10A1 Murine Leukemia Virus Leukemogenicity
Published in Journal of Virology (01-01-2007)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The MADS transcription factor Mef2c is a pivotal modulator of myeloid cell fate
Published in Blood (01-05-2008)“…Mef2c is a MADS (MCM1-agamous–deficient serum response factor) transcription factor best known for its role in muscle and cardiovascular development. A causal…”
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Immunologic hurdles of therapeutic stem cell transplantation
Published in Biological chemistry (01-10-2009)“…Detailed knowledge of the immunologic properties of embryonic stem (ES) cells is a prerequisite for safe applications of ES cell-based regenerative medicine…”
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