Search Results - "Engelman, D"

Postoperative care: who should look after patients following surgery? by Fletcher, N., Engelman, D. T.

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The gut microbiota-derived metabolite trimethylamine N-oxide is elevated in Alzheimer's disease by Vogt, Nicholas M, Romano, Kymberleigh A, Darst, Burcu F, Engelman, Corinne D, Johnson, Sterling C, Carlsson, Cynthia M, Asthana, Sanjay, Blennow, Kaj, Zetterberg, Henrik, Bendlin, Barbara B, Rey, Federico E

“…Trimethylamine N-oxide (TMAO), a small molecule produced by the metaorganismal metabolism of dietary choline, has been implicated in human disease…”
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Scabies in the developing world–-its prevalence, complications, and management by Hay, R.J., Steer, A.C., Engelman, D., Walton, S.

“…Scabies remains one of the commonest of skin diseases seen in developing countries. Although its distribution is subject to a cycle of infection, with peaks…”
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Estimating the global burden of scabies: what else do we need? by Cox, V., Fuller, L.C., Engelman, D., Steer, A., Hay, R.J.

“…Summary Scabies is one of the most common disorders identified in any estimate of global skin disease prevalence. Furthermore, quantifying its impact on…”
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Using recursive feature elimination in random forest to account for correlated variables in high dimensional data by Darst, Burcu F, Malecki, Kristen C, Engelman, Corinne D

“…Random forest (RF) is a machine-learning method that generally works well with high-dimensional problems and allows for nonlinear relationships between…”
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Association Between Common Variants in RBFOX1, an RNA-Binding Protein, and Brain Amyloidosis in Early and Preclinical Alzheimer Disease by Raghavan, Neha S, Dumitrescu, Logan, Mormino, Elizabeth, Mahoney, Emily R, Lee, Annie J, Gao, Yizhe, Bilgel, Murat, Goldstein, David, Harrison, Theresa, Engelman, Corinne D, Saykin, Andrew J, Whelan, Christopher D, Liu, Jimmy Z, Jagust, William, Albert, Marilyn, Johnson, Sterling C, Yang, Hyun-Sik, Johnson, Keith, Aisen, Paul, Resnick, Susan M, Sperling, Reisa, De Jager, Philip L, Schneider, Julie, Bennett, David A, Schrag, Matthew, Vardarajan, Badri, Hohman, Timothy J, Mayeux, Richard

“…Genetic studies of Alzheimer disease have focused on the clinical or pathologic diagnosis as the primary outcome, but little is known about the genetic basis…”
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The Wisconsin Registry for Alzheimer's Prevention: A review of findings and current directions by Johnson, Sterling C., Koscik, Rebecca L., Jonaitis, Erin M., Clark, Lindsay R., Mueller, Kimberly D., Berman, Sara E., Bendlin, Barbara B., Engelman, Corinne D., Okonkwo, Ozioma C., Hogan, Kirk J., Asthana, Sanjay, Carlsson, Cynthia M., Hermann, Bruce P., Sager, Mark A.

“…The Wisconsin Registry for Alzheimer's Prevention is a longitudinal observational cohort study enriched with persons with a parental history (PH) of probable…”
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Systematic review of the diagnosis of scabies in therapeutic trials by Thompson, M. J., Engelman, D., Gholam, K., Fuller, L. C., Steer, A. C.

“…Summary Human scabies (infestation with the mite Sarcoptes scabiei var hominis) causes a significant disease burden worldwide, yet there are no agreed…”
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Genetic and Environmental Determinants of 25-Hydroxyvitamin D and 1,25-Dihydroxyvitamin D Levels in Hispanic and African Americans by Engelman, Corinne D., Fingerlin, Tasha E., Langefeld, Carl D., Hicks, Pamela J., Rich, Stephen S., Wagenknecht, Lynne E., Bowden, Donald W., Norris, Jill M.

“…Context: Vitamin D deficiency is associated with many adverse health outcomes, yet little is known about the genetic epidemiology of vitamin D or its…”
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Identification of plasma metabolites associated with modifiable risk factors and endophenotypes reflecting Alzheimer’s disease pathology by Dong, Ruocheng, Denier-Fields, Diandra N., Van Hulle, Carol A., Kollmorgen, Gwendlyn, Suridjan, Ivonne, Wild, Norbert, Lu, Qiongshi, Anderson, Rozalyn M., Zetterberg, Henrik, Blennow, Kaj, Carlsson, Cynthia M., Johnson, Sterling C., Engelman, Corinne D.

“…Modifiable factors can influence the risk for Alzheimer’s disease (AD) and serve as targets for intervention; however, the biological mechanisms linking these…”
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Pathway-Specific Polygenic Risk Scores as Predictors of Amyloid-β Deposition and Cognitive Function in a Sample at Increased Risk for Alzheimer's Disease by Darst, Burcu F, Koscik, Rebecca L, Racine, Annie M, Oh, Jennifer M, Krause, Rachel A, Carlsson, Cynthia M, Zetterberg, Henrik, Blennow, Kaj, Christian, Bradley T, Bendlin, Barbara B, Okonkwo, Ozioma C, Hogan, Kirk J, Hermann, Bruce P, Sager, Mark A, Asthana, Sanjay, Johnson, Sterling C, Engelman, Corinne D

“…Polygenic risk scores (PRSs) have been used to combine the effects of variants with small effects identified by genome-wide association studies. We explore the…”
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Genetic evidence for role of carotenoids in age-related macular degeneration in the Carotenoids in Age-Related Eye Disease Study (CAREDS) by Meyers, Kristin J, Mares, Julie A, Igo, Jr, Robert P, Truitt, Barbara, Liu, Zhe, Millen, Amy E, Klein, Michael, Johnson, Elizabeth J, Engelman, Corinne D, Karki, Chitra K, Blodi, Barbara, Gehrs, Karen, Tinker, Lesley, Wallace, Robert, Robinson, Jennifer, LeBlanc, Erin S, Sarto, Gloria, Bernstein, Paul S, SanGiovanni, John Paul, Iyengar, Sudha K

“…We tested variants in genes related to lutein and zeaxanthin status for association with age-related macular degeneration (AMD) in the Carotenoids in…”
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Author Correction: Whole-body metabolic modelling reveals microbiome and genomic interactions on reduced urine formate levels in Alzheimer’s disease by Martinelli, Filippo, Heinken, Almut, Henning, Ann-Kristin, Ulmer, Maria A., Hensen, Tim, González, Antonio, Arnold, Matthias, Asthana, Sanjay, Budde, Kathrin, Engelman, Corinne D., Estaki, Mehrbod, Grabe, Hans-Jörgen, Heston, Margo B., Johnson, Sterling, Kastenmüller, Gabi, Martino, Cameron, McDonald, Daniel, Rey, Federico E., Kilimann, Ingo, Peters, Olive, Wang, Xiao, Spruth, Eike Jakob, Schneider, Anja, Fliessbach, Klaus, Wiltfang, Jens, Hansen, Niels, WenzelGlanz, Buerger, Katharina, Janowitz, Daniel, Laske, Christoph, Munk, Matthias H., Spottke, Annika, Roy, Nina, Nauck, Matthias, Teipel, Stefan, Knight, Rob, Kaddurah-Daouk, Rima F., Bendlin, Barbara B., Hertel, Johannes, Thiele, Ines

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KLOTHO heterozygosity attenuates APOE4-related amyloid burden in preclinical AD by Erickson, Claire M, Schultz, Stephanie A, Oh, Jennifer M, Darst, Burcu F, Ma, Yue, Norton, Derek, Betthauser, Tobey, Gallagher, Catherine L, Carlsson, Cynthia M, Bendlin, Barbara B, Asthana, Sanjay, Hermann, Bruce P, Sager, Mark A, Blennow, Kaj, Zetterberg, Henrik, Engelman, Corinne D, Christian, Bradley T, Johnson, Sterling C, Dubal, Dena B, Okonkwo, Ozioma C

“…OBJECTIVETo examine whether the KLOTHO gene variant KL-VS attenuates APOE4-associated β-amyloid (Aβ) accumulation in a late-middle-aged cohort enriched with…”
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Principal components from untargeted cerebrospinal fluid metabolomics associated with Alzheimer's disease biomarkers by Dong, Ruocheng, Denier-Fields, Diandra N., Lu, Qiongshi, Suridjan, Ivonne, Kollmorgen, Gwendlyn, Wild, Norbert, Betthauser, Tobey James, Carlsson, Cynthia M., Asthana, Sanjay, Johnson, Sterling C., Zetterberg, Henrik, Blennow, Kaj, Engelman, Corinne D.

“…•Principal component analysis was conducted for untargeted CSF metabolites.•CSF metabolite principal components were associated with AD biomarkers such as…”
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The effect of rare variants in TREM2 and PLD3 on longitudinal cognitive function in the Wisconsin Registry for Alzheimer's Prevention by Engelman, Corinne D., Darst, Burcu F., Bilgel, Murat, Vasiljevic, Eva, Koscik, Rebecca L., Jedynak, Bruno M., Johnson, Sterling C.

“…Recent studies have found an association between functional variants in TREM2 and PLD3 and Alzheimer's disease (AD), but their effect on cognitive function is…”
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Telomere Length Varies By DNA Extraction Method: Implications for Epidemiologic Research by CUNNINGHAM, Julie M, JOHNSON, Ruth A, BARON, John A, POTTER, John D, HAILE, Robert, BUCHANAN, Daniel D, JENKINS, Mark A, RIDER, David N, THIBODEAU, Stephen N, PETERSEN, Gloria M, BOARDMAN, Lisa A, LITZELMAN, Kristin, SKINNER, Halcyon G, SONGWON SEO, ENGELMAN, Corinne D, VANDERBOOM, Russell J, KIMMEL, Grace W, GANGNON, Ronald E, RIEGERT-JOHNSON, Douglas L

“…Both shorter and longer telomeres in peripheral blood leukocyte (PBL) DNA have been associated with cancer risk. However, associations remain inconsistent…”
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CSF metabolites associated with biomarkers of Alzheimer's disease pathology by Dong, Ruocheng, Lu, Qiongshi, Kang, Hyunseung, Suridjan, Ivonne, Kollmorgen, Gwendlyn, Wild, Norbert, Deming, Yuetiva, Van Hulle, Carol A, Anderson, Rozalyn M, Zetterberg, Henrik, Blennow, Kaj, Carlsson, Cynthia M, Asthana, Sanjay, Johnson, Sterling C, Engelman, Corinne D

“…Metabolomics technology facilitates studying associations between small molecules and disease processes. Correlating metabolites in cerebrospinal fluid (CSF)…”
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Whole-body metabolic modelling reveals microbiome and genomic interactions on reduced urine formate levels in Alzheimer’s disease by Martinelli, Filippo, Heinken, Almut, Henning, Ann-Kristin, Ulmer, Maria A., Hensen, Tim, González, Antonio, Arnold, Matthias, Asthana, Sanjay, Budde, Kathrin, Engelman, Corinne D., Estaki, Mehrbod, Grabe, Hans-Jörgen, Heston, Margo B., Johnson, Sterling, Kastenmüller, Gabi, Martino, Cameron, McDonald, Daniel, Rey, Federico E., Kilimann, Ingo, Peters, Olive, Wang, Xiao, Spruth, Eike Jakob, Schneider, Anja, Fliessbach, Klaus, Wiltfang, Jens, Hansen, Niels, Glanz, Wenzel, Buerger, Katharina, Janowitz, Daniel, Laske, Christoph, Munk, Matthias H., Spottke, Annika, Roy, Nina, Nauck, Matthias, Teipel, Stefan, Knight, Rob, Kaddurah-Daouk, Rima F., Bendlin, Barbara B., Hertel, Johannes, Thiele, Ines

“…In this study, we aimed to understand the potential role of the gut microbiome in the development of Alzheimer's disease (AD). We took a multi-faceted approach…”
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Analysis of copy number variation in dogs implicates genomic structural variation in the development of anterior cruciate ligament rupture by Binversie, Emily E, Baker, Lauren A, Engelman, Corinne D, Hao, Zhengling, Moran, John J, Piazza, Alexander M, Sample, Susannah J, Muir, Peter

“…Anterior cruciate ligament (ACL) rupture is an important condition of the human knee. Second ruptures are common and societal costs are substantial. Canine…”
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