Search Results - "Engelhardt, Rupert"

Factors Influencing [F‐18] 2‐Fluoro‐2‐Deoxy‐d‐Glucose (F‐18 FDG) Uptake in Melanoma Cells: The Role of Proliferation Rate, Viability, Glucose Transporter Expression and Hexokinase Activity by Yamada, Kiyoshi, Brink, Ingo, Bissé, Emmanuel, Epting, Thomas, Engelhardt, Rupert

“…Using human (SK‐MEL 23, SK‐MEL 24 and G361) and murine (B16) melanoma cell lines, the coregulatory potential of the uptake of the positron emission tomography…”
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Factors Influencing [F‐18] 2‐Fluoro‐2‐Deoxy‐d‐Glucose (F‐18 FDG) Accumulation in Melanoma Cells: Is FDG a Substrate of Multidrug Resistance (MDR)? by Yamada, Kiyoshi, Brink, Ingo, Engelhardt, Rupert

“…In order to specify the influence of multidrug‐resistance (MDR) on the accumulation of the PET tracer, F‐18 FDG ([Fluorine‐18] 2‐fluoro‐2‐deoxy‐d‐glucose, in…”
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Individualized Patient Dosing in Phase I Clinical Trials: The Role of Escalation With Overdose Control in PNU-214936 by CHENG, Jonathan D, BABB, James S, WEINER, Louis M, ROGATKO, André, LAUGER, Corey, AAMDAL, Steinar, ROBERT, Francisco, ENGELHARDT, Lars Rupert, FERNBERG, Olov, SCHILLER, Joan, FORSBERY, Goran, ALPAUGH, R. Katherine

“…A patient-specific dose-escalation scheme using a Bayesian model of Escalation with Overdose Control (EWOC) was conducted to establish the maximum tolerated…”
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Immune response as a possible mechanism of long-lasting disease control in spontaneous remission of MLL/AF9-positive acute myeloid leukemia by Müller-Schmah, Claudia, Solari, Leticia, Weis, Roland, Pfeifer, Dietmar, Scheibenbogen, Carmen, Trepel, Martin, May, Annette M., Engelhardt, Rupert, Lübbert, Michael

“…Spontaneous complete remission (CR) is a rare, poorly understood phenomenon in acute myeloid leukemia (AML). We describe the 10-year follow-up of a patient…”
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Hematologic and molecular spontaneous remission following sepsis in acute monoblastic leukemia with translocation (9;11): a case report and review of the literature by Müller, Claudia I., Trepel, Martin, Kunzmann, Regina, Lais, Angela, Engelhardt, Rupert, Lübbert, Michael

“…:  Spontaneous remission in patients with acute myeloid leukemia (AML) is a rarely reported phenomenon of usually short duration. The etiology remains unclear,…”
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Myelodysplastic syndrome in transformation to acute myeloid leukemia presenting with diabetes insipidus: due to pituitary infiltration association with abnormalities of chromosomes 3 and 7 by Müller, Claudia I., Engelhardt, Monika, Laubenberger, Jörg, Kunzmann, Regina, Engelhardt, Rupert, Lübbert, Michael

“…: A 31‐yr‐old woman with myelodysplastic syndrome (MDS) in transformation to acute myeloid leukemia (AML) presented with initial symptoms of polyuria and…”
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Phase I trial of intravenously administered endotoxin (Salmonella abortus equi) in cancer patients by Engelhardt, R, Mackensen, A, Galanos, C

“…We report a phase I study in cancer patients being treated with i.v. bolus injections of highly purified lipopolysaccharide (LPS) Salmonella abortus equi…”
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Downregulation of the Proinflammatory Cytokine Response to Endotoxin by Pretreatment With the Nontoxic Lipid A Analog SDZ MRL 953 in Cancer Patients by Kiani, Alexander, Tschiersch, Astrid, Gaboriau, Elke, Otto, Florian, Seiz, Alexander, Knopf, Hans-Peter, Stütz, Peter, Färber, Lothar, Haus, Ulrike, Galanos, Chris, Mertelsmann, Roland, Engelhardt, Rupert

“…Interfering with the endotoxin-mediated cytokine cascade is thought to be a promising approach to prevent septic complications in gram-negative infections. The…”
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Complete response of metastatic renal cell carcinoma to low-dose interferon-? treatment by Otto, Florian, Mackensen, Andreas, Mertelsmann, Roland, Engelhardt, Rupert

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Management of acute myeloid leukaemia following myelodysplastic syndrome in a kidney graft recipient by WÜRTHNER, J, RUMP, L. C, GROTZ, W, ENGELHARDT, R, LÜBBERT, M

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Complete response of metastatic renal cell carcinoma to low-dose interferon-γ treatment by OTTO, F, MACKENSEN, A, METERTELSMANN, R, ENGELHARDT, R

“…The course of metastatic renal cell carcinoma may be positively influenced by immunotherapeutic agents. We report a case of renal cell carcinoma showing a…”
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Treatment of cancer patients with endotoxin induces release of endogenous cytokines by Mackensen, A, Galanos, C, Engelhardt, R

“…This study sought to determine whether endogenous tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6) and granulocyte-colony-stimulating factor…”
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Downregulation of the proinflammatory cytokine response to endotoxin by pretreatment with the nontoxic lipid A analog SDZ MRL 953 in cancer patients by KIANI, A, TSCHIERSCH, A, MERTELSMANN, R, ENGELHARDT, R, GABORIAU, E, OTTO, F, SEIZ, A, KNOPF, H.-P, STÜTZ, P, FÄRBER, L, HAUS, U, GALANOS, C

“…Interfering with the endotoxin-mediated cytokine cascade is thought to be a promising approach to prevent septic complications in gram-negative infections. The…”
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Selective cytotoxicity of a phenolic melanin precursor, 4-S-cysteaminylphenol, on in vitro melanoma cells by Yamada, K, Jimbow, K, Engelhardt, R, Ito, S

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Hematologic and molecular spontaneous remission following sepsis in acute monoblastic leukemia with translocation (9;11): a case report and review of the literature by Müller, Claudia I., Trepel, Martin, Kunzmann, Regina, Lais, Angela, Engelhardt, Rupert, Lübbert, Michael

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Biological response to intravenously administered endotoxin in patients with advanced cancer by Engelhardt, R, Mackensen, A, Galanos, C, Andreesen, R

“…The purpose of the study was to evaluate the toxicity and biological activity of highly purified lipopolysaccharide (LPS) administered intravenously to cancer…”
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Myelodysplastic syndrome in transformation to acute myeloid leukemia presenting with diabetes insipidus: due to pituitary infiltration association with abnormalities of chromosomes 3 and 7 by Müller, Claudia I., Engelhardt, Monika, Laubenberger, Jörg, Kunzmann, Regina, Engelhardt, Rupert, Lübbert, Michael

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Glucosephosphate Isomerase Deficiency: Evidence for In Vivo Instability of an Enzyme Variant With Hemolysis by Arnold, Heidwolf, Blume, Karl-Georg, Engelhardt, Rupert, Löhr, Georg Wilhelm

“…Pathogenesis of hemolysis in glucose-phosphate isomerase (GPI) deficiency was studied. Red cell populations of different ages were obtained by density…”
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Hereditary deficiency of glucosephosphate isomerase as a cause of nonspherocytic hemolytic anemia by Löhr, G W, Arnold, H, Blume, K G, Engelhardt, R, Beutler, E

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