Search Results - "Engelhardt, Clara"

Chronic social defeat stress in female mice leads to sex-specific behavioral and neuroendocrine effects by van Doeselaar, Lotte, Yang, Huanqing, Bordes, Joeri, Brix, Lea, Engelhardt, Clara, Tang, Fiona, Schmidt, Mathias V

“…Over the years, it has become increasingly clear that males and females respond differently towards environmental stressors, highlighting the importance of…”
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Automatically annotated motion tracking identifies a distinct social behavioral profile following chronic social defeat stress by Bordes, Joeri, Miranda, Lucas, Reinhardt, Maya, Narayan, Sowmya, Hartmann, Jakob, Newman, Emily L., Brix, Lea Maria, van Doeselaar, Lotte, Engelhardt, Clara, Dillmann, Larissa, Mitra, Shiladitya, Ressler, Kerry J., Pütz, Benno, Agakov, Felix, Müller-Myhsok, Bertram, Schmidt, Mathias V.

“…Severe stress exposure increases the risk of stress-related disorders such as major depressive disorder (MDD). An essential characteristic of MDD is the…”
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The co-chaperone Fkbp5 shapes the acute stress response in the paraventricular nucleus of the hypothalamus of male mice by Häusl, Alexander S., Brix, Lea M., Hartmann, Jakob, Pöhlmann, Max L., Lopez, Juan-Pablo, Menegaz, Danusa, Brivio, Elena, Engelhardt, Clara, Roeh, Simone, Bajaj, Thomas, Rudolph, Lisa, Stoffel, Rainer, Hafner, Kathrin, Goss, Hannah M., Reul, Johannes M. H. M., Deussing, Jan M., Eder, Matthias, Ressler, Kerry J., Gassen, Nils C., Chen, Alon, Schmidt, Mathias V.

“…Disturbed activation or regulation of the stress response through the hypothalamic-pituitary-adrenal (HPA) axis is a fundamental component of multiple…”
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Pharmacological Modulation of the Psychiatric Risk Factor FKBP51 Alters Efficiency of Common Antidepressant Drugs by Pöhlmann, Max L, Häusl, Alexander S, Harbich, Daniela, Balsevich, Georgia, Engelhardt, Clara, Feng, Xixi, Breitsamer, Michaela, Hausch, Felix, Winter, Gerhard, Schmidt, Mathias V

“…Despite a growing body of research over the last few decades, mental disorders, including anxiety disorders or depression, are still one of the most prevalent…”
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Contribution of the co-chaperone FKBP51 in the ventromedial hypothalamus to metabolic homeostasis in male and female mice by Brix, Lea M., Toksöz, Irmak, Aman, London, Kovarova, Veronika, Springer, Margherita, Bordes, Joeri, van Doeselaar, Lotte, Engelhardt, Clara, Häusl, Alexander S., Narayan, Sowmya, Sterlemann, Vera, Yang, Huanqing, Deussing, Jan M., Schmidt, Mathias V.

“…Steroidogenic factor 1 (SF1) expressing neurons in the ventromedial hypothalamus (VMH) have been directly implicated in whole-body metabolism and in the onset…”
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Lack of FKBP51 Shapes Brain Structure and Connectivity in Male Mice by Engelhardt, Clara, Boulat, Benoit, Czisch, Michael, Schmidt, Mathias V.

“…Background Stress exposure as well as psychiatric disorders are often associated with abnormalities in brain structure or connectivity. The co‐chaperone…”
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Metabolic effects of early life stress and pre‐pregnancy obesity are long lasting and sex specific in mice by Brix, Lea M., Monleon, Daniel, Collado, Maria Carmen, Ederveen, Thomas H. A., Toksöz, Irmak, Bordes, Joeri, Doeselaar, Lotte, Engelhardt, Clara, Mitra, Shiladitya, Narayan, Sowmya, Schmidt, Mathias V.

“…Early life stress (ELS) is associated with metabolic, cognitive, and psychiatric diseases and has a very high prevalence, highlighting the urgent need for a…”
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Sex-specific and opposed effects of FKBP51 in glutamatergic and GABAergic neurons: Implications for stress susceptibility and resilience by van Doeselaar, Lotte, Stark, Tibor, Mitra, Shiladitya, Yang, Huanqing, Bordes, Joeri, Stolwijk, Linda, Engelhardt, Clara, Kovarova, Veronika, Narayan, Sowmya, Brix, Lea M, Springer, Margherita, Deussing, Jan M, Lopez, Juan Pablo, Czisch, Michael, Schmidt, Mathias V

“…Mental health disorders often arise as a combination of environmental and genetic factors. The gene, encoding the GR co-chaperone FKBP51, has been uncovered as…”
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The co-chaperone FKBP51 modulates HPA axis activity and age-related maladaptation of the stress system in pituitary proopiomelanocortin cells by Brix, Lea M., Häusl, Alexander S., Toksöz, Irmak, Bordes, Joeri, van Doeselaar, Lotte, Engelhardt, Clara, Narayan, Sowmya, Springer, Margherita, Sterlemann, Vera, Deussing, Jan M., Chen, Alon, Schmidt, Mathias V.

“…Glucocorticoid (GC)-mediated negative feedback of the hypothalamic-pituitary-adrenal (HPA) axis, the body’s physiological stress response system, is tightly…”
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Single-cell molecular profiling of all three components of the HPA axis reveals adrenal ABCB1 as a regulator of stress adaptation by Lopez, Juan Pablo, Brivio, Elena, Santambrogio, Alice, De Donno, Carlo, Kos, Aron, Peters, Miriam, Rost, Nicolas, Czamara, Darina, Brückl, Tanja M, Roeh, Simone, Pöhlmann, Max L, Engelhardt, Clara, Ressle, Andrea, Stoffel, Rainer, Tontsch, Alina, Villamizar, Javier M, Reincke, Martin, Riester, Anna, Sbiera, Silviu, Fassnacht, Martin, Mayberg, Helen S, Craighead, W Edward, Dunlop, Boadie W, Nemeroff, Charles B, Schmidt, Mathias V, Binder, Elisabeth B, Theis, Fabian J, Beuschlein, Felix, Andoniadou, Cynthia L, Chen, Alon

“…Chronic activation and dysregulation of the neuroendocrine stress response have severe physiological and psychological consequences, including the development…”
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FKBP51 in the Oval Bed Nucleus of the Stria Terminalis Regulates Anxiety-Like Behavior by Engelhardt, Clara, Tang, Fiona, Elkhateib, Radwa, Bordes, Joeri, Brix, Lea Maria, van Doeselaar, Lotte, Häusl, Alexander S, Pöhlmann, Max L, Schraut, Karla, Yang, Huanqing, Chen, Alon, Deussing, Jan M, Schmidt, Mathias V

“…The cochaperone FKBP51, encoded by the gene, has been identified as central risk factor for anxiety-related disorders and stress system dysregulation. In the…”
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Poster summaries by Krist, Gabriela, Belishki, Stefan, Bidarra, Ana, Antunes, Pedro, Rocha, Fernando, Chan, Emma, Cheung, Angela, Tsang, Alice, Sam, Louise, Chlumská, Štěpánka, Novotná, Miroslava, Šefcu˚, Radka, Coelho, Daniela, Villa, Mayra Elitania Galan, Eipper, Paul-Bernhard, Elnaggar, Abdelrazek, Fitzsimons, Paul, Osticioli, Iacopo, Watkins, Ken, Eremin, Katherine, Chloros, Jessica, Mason, Robert, Chang, Angela, McWilliams, Mary, Sigel, Anthony, Yoltar, Aysin, Fischer, Andrea, van Giffen, Astrid, Eggert, Gerhard, Frank, David, Franková, Jarmila, Frieden, Vanessa, Radujkovic, Sonja, Rütt, Dunja, Schulz, Anette, Mengshoel, Karen, Kempton, Hanne Moltubakk, Gianoli, Savina, Fulgoni, Giovanna, Ghizzoni, Francesca, Salvatori, Sabrina, Weber, Johannes, Guzowska, Anna, Heginbotham, Arlen, Piening, Heinrich, Von Engelhardt, Clara, Grzywacz, Cecily, Hughes, Gary, Jagić, Romana, Cvetković, Siniša, Bogović, Srebrenka, Ravenel, Nancie, Kita, Yuko, Fructuoso Hernández, Gonzalo J., Matsui, Toshiya, Montes, Luis Torres, García, Manuel Reyes, Kousoulou, Tatiana, Kuvvetli, Filiz, Kilercik, Ays¸e Aldemir, Öncel, Çinar, Taralp, Alpay, Özgörüs¸, Nurçin Kural, Liu, Wai-Sum, Ljubic, Valentina, Kautek, Wolfgang, Buecker, Michael, Chan, Roland, Ramnauth, Belinda T. K., Roby, Thomas, Friedman, Leslie, Alberti, Livia, Caldi, Cristina, Carbonara, Ermanno, Chaouali, Moheddine, Sauerberg, Marie Louise, Broecke, Lara, Marchant, Ray, Stock, Alison, Melcher, Michael, Wei, Shuya, Schwarz, Cynthia, Bori, Tahereh Shisheh, Abed-Esfahani, Abbs, Škarić, Ksenija, Solberg, Kristin, Risåsen, Geir Thomas, Takeda, Akiko, Tsuchiya, Nobutaka, Dowsett, Nicky, Izadan, Hossein, van Lookeren, Kate, Nobbs, James, Pak, Lina, Top, Marijke, Tsipotas, Dimitris, Michalaros, Christoforos, Saulesleja, Indra, Knothe, Florian, Wang, Quanyu

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