Reproducibility and relative validity of a food frequency questionnaire to estimate intake of dietary phylloquinone and menaquinones
Background/Objectives: This study aims to investigate the reproducibility and relative validity of the Dutch food frequency questionnaire (FFQ), to estimate intake of dietary phylloquinone and menaquinones compared with 24-h dietary recalls (24HDRs) and plasma markers of vitamin K status. Subjects/M...
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Published in: | European journal of clinical nutrition Vol. 71; no. 12; pp. 1423 - 1428 |
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Main Authors: | , , , , , , , , , |
Format: | Journal Article |
Language: | English |
Published: |
London
Nature Publishing Group UK
01-12-2017
Nature Publishing Group |
Subjects: | |
Online Access: | Get full text |
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Summary: | Background/Objectives:
This study aims to investigate the reproducibility and relative validity of the Dutch food frequency questionnaire (FFQ), to estimate intake of dietary phylloquinone and menaquinones compared with 24-h dietary recalls (24HDRs) and plasma markers of vitamin K status.
Subjects/Methods:
In a cross-sectional study among 63 men and 58 women, the FFQ was completed three times over a 1-year period and the reproducibility was calculated over these measurements. Twelve-monthly 24HDR were collected to estimate relative validity. In addition, the relative validity of the FFQ, compared with plasma phylloquinone and desphospho-uncarboxylated matrix Gla protein (dpucMGP), was assessed cross-sectionally among 507 postmenopausal women.
Results:
Intraclass correlations showed a good reproducibility, with correlations ranging from 0.65 to 0.83. The relative validity for phylloquinone intake compared with 24HDR was lower for women (r
s
=0.28) than men (r
s
=0.40). The relative validity, compared with 24HDR, for intake of short-chain menaquinones were ranging between 0.30 and 0.34. Long-chain menaquinones showed good relative validity (r
s
=0.60–0.69). Plasma phylloquinone concentrations were weakly correlated with phylloquinone intake (r
s
=0.16 (0.07-0.24). Plasma dpucMGP was negatively but weakly correlated with phylloquinone intake (r
s
=−0.09 (−0.18; −0.01)) and long-chain menaquinones (r
s
=−0.13 (−0.21; −0.04)), but not with short-chain menaquinones (r
s
=−0.04 (−0.13; 0.05)).
Conclusions:
The FFQ is reproducible to rank subjects for phylloquinone and menaquinone intake.The relative validity of our FFQ, compared with 24HDR, to estimate intake of phylloquinone and short-chain menaquinones was low, but the relative validity for long-chain menaquinones was good. The relative validity of our FFQ, compared with plasma phylloquinone and dpucMGP, was relatively low for both phylloquinone and menaquinone intake. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0954-3007 1476-5640 |
DOI: | 10.1038/ejcn.2017.121 |