Search Results - "Engelberg, Klemens"

Proteomic characterization of the Toxoplasma gondii cytokinesis machinery portrays an expanded hierarchy of its assembly and function by Engelberg, Klemens, Bechtel, Tyler, Michaud, Cynthia, Weerapana, Eranthie, Gubbels, Marc-Jan

“…The basal complex (BC) is essential for T. gondii cell division but mechanistic details are lacking. Here we report a reciprocal proximity based biotinylation…”
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Transcriptional profiling of growth perturbations of the human malaria parasite Plasmodium falciparum by Gilberger, Tim-W, Bozdech, Zbynek, Hu, Guangan, Cabrera, Ana, Kono, Maya, Mok, Sachel, Chaal, Balbir K, Haase, Silvia, Engelberg, Klemens, Cheemadan, Sabna, Spielmann, Tobias, Preiser, Peter R

“…We have yet to identify the functions of the majority of genes of Plasmodium falciparum , the causative agent of malaria. Hu et al . profile transcriptional…”
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The Modular Circuitry of Apicomplexan Cell Division Plasticity by Gubbels, Marc-Jan, Coppens, Isabelle, Zarringhalam, Kourosh, Duraisingh, Manoj T, Engelberg, Klemens

“…The close-knit group of apicomplexan parasites displays a wide variety of cell division modes, which differ between parasites as well as between different life…”
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Fussing About Fission: Defining Variety Among Mainstream and Exotic Apicomplexan Cell Division Modes by Gubbels, Marc-Jan, Keroack, Caroline D, Dangoudoubiyam, Sriveny, Worliczek, Hanna L, Paul, Aditya S, Bauwens, Ciara, Elsworth, Brendan, Engelberg, Klemens, Howe, Daniel K, Coppens, Isabelle, Duraisingh, Manoj T

“…Cellular reproduction defines life, yet our textbook-level understanding of cell division is limited to a small number of model organisms centered around…”
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A Member of the Ferlin Calcium Sensor Family Is Essential for Toxoplasma gondii Rhoptry Secretion by Coleman, Bradley I, Saha, Sudeshna, Sato, Seiko, Engelberg, Klemens, Ferguson, David J P, Coppens, Isabelle, Lodoen, Melissa B, Gubbels, Marc-Jan

“…Invasion of host cells by apicomplexan parasites such as is critical for their infectivity and pathogenesis. In , secretion of essential egress, motility, and…”
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Toxoplasma gondii’s Basal Complex: The Other Apicomplexan Business End Is Multifunctional by Gubbels, Marc-Jan, Ferguson, David J. P., Saha, Sudeshna, Romano, Julia D., Chavan, Suyog, Primo, Vincent A., Michaud, Cynthia, Coppens, Isabelle, Engelberg, Klemens

“…The Apicomplexa are famously named for their apical complex, a constellation of organelles at their apical end dedicated to invasion of their host cells. In…”
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Hierarchical phosphorylation of apical membrane antigen 1 is required for efficient red blood cell invasion by malaria parasites by Prinz, Boris, Harvey, Katherine L., Wilcke, Louisa, Ruch, Ulrike, Engelberg, Klemens, Biller, Laura, Lucet, Isabelle, Erkelenz, Steffen, Heincke, Dorothee, Spielmann, Tobias, Doerig, Christian, Kunick, Conrad, Crabb, Brendan S., Gilson, Paul R., Gilberger, Tim W.

“…Central to the pathogenesis of malaria is the proliferation of Plasmodium falciparum parasites within human erythrocytes. Parasites invade erythrocytes via a…”
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Functional analysis of the leading malaria vaccine candidate AMA-1 reveals an essential role for the cytoplasmic domain in the invasion process by Treeck, Moritz, Zacherl, Sonja, Herrmann, Susann, Cabrera, Ana, Kono, Maya, Struck, Nicole S, Engelberg, Klemens, Haase, Silvia, Frischknecht, Friedrich, Miura, Kota, Spielmann, Tobias, Gilberger, Tim W

“…A key process in the lifecycle of the malaria parasite Plasmodium falciparum is the fast invasion of human erythrocytes. Entry into the host cell requires the…”
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Sequence requirements for the export of the Plasmodium falciparum Maurer's clefts protein REX2 by Haase, Silvia, Herrmann, Susann, Grüring, Christof, Heiber, Arlett, Jansen, Pascal W, Langer, Christine, Treeck, Moritz, Cabrera, Ana, Bruns, Caroline, Struck, Nicole S, Kono, Maya, Engelberg, Klemens, Ruch, Ulrike, Stunnenberg, Hendrik G, Gilberger, Tim-Wolf, Spielmann, Tobias

“…A short motif termed Plasmodium export element (PEXEL) or vacuolar targeting signal (VTS) characterizes Plasmodium proteins exported into the host cell. These…”
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The apical annuli of Toxoplasma gondii are composed of coiled‐coil and signalling proteins embedded in the inner membrane complex sutures by Engelberg, Klemens, Chen, Chun‐Ti, Bechtel, Tyler, Sánchez Guzmán, Victoria, Drozda, Allison A., Chavan, Suyog, Weerapana, Eranthie, Gubbels, Marc‐Jan

“…The apical annuli are among the most intriguing and understudied structures in the cytoskeleton of the apicomplexan parasite Toxoplasma gondii. We mapped the…”
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The apical annuli of Toxoplasma gondii are composed of coiled-coil and signaling proteins embedded in the IMC sutures by Engelberg, Klemens, Chen, Chun-Ti, Bechtel, Tyler, Guzmán, Victoria Sánchez, Drozda, Allison A., Chavan, Suyog, Weerapana, Eranthie, Gubbels, Marc-Jan

“…The apical annuli are among the most intriguing and understudied structures in the cytoskeleton of the apicomplexan parasite Toxoplasma gondii . We mapped the…”
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Parasite Calcineurin Regulates Host Cell Recognition and Attachment by Apicomplexans by Paul, Aditya S., Saha, Sudeshna, Engelberg, Klemens, Jiang, Rays H.Y., Coleman, Bradley I., Kosber, Aziz L., Chen, Chun-Ti, Ganter, Markus, Espy, Nicole, Gilberger, Tim W., Gubbels, Marc-Jan, Duraisingh, Manoj T.

“…Apicomplexans invade a variety of metazoan host cells through mechanisms involving host cell receptor engagement and secretion of parasite factors…”
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Evolution and architecture of the inner membrane complex in asexual and sexual stages of the malaria parasite by Kono, Maya, Herrmann, Susann, Loughran, Noeleen B, Cabrera, Ana, Engelberg, Klemens, Lehmann, Christine, Sinha, Dipto, Prinz, Boris, Ruch, Ulrike, Heussler, Volker, Spielmann, Tobias, Parkinson, John, Gilberger, Tim W

“…The inner membrane complex (IMC) is a unifying morphological feature of all alveolate organisms. It consists of flattened vesicles underlying the plasma…”
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Migratory activation of parasitized dendritic cells by the protozoan Toxoplasma gondii 14‐3‐3 protein by Weidner, Jessica M., Kanatani, Sachie, Uchtenhagen, Hannes, Varas‐Godoy, Manuel, Schulte, Tim, Engelberg, Klemens, Gubbels, Marc‐Jan, Sun, He Song, Harrison, Rene E., Achour, Adnane, Barragan, Antonio

“…Summary The obligate intracellular parasite Toxoplasma gondii exploits cells of the immune system to disseminate. Upon infection, parasitized dendritic cells…”
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A MORN1‐associated HAD phosphatase in the basal complex is essential for Toxoplasma gondii daughter budding by Engelberg, Klemens, Ivey, F. Douglas, Lin, Angela, Kono, Maya, Lorestani, Alexander, Faugno‐Fusci, Dave, Gilberger, Tim‐Wolf, White, Michael, Gubbels, Marc‐Jan

“…Summary Apicomplexan parasites replicate by several budding mechanisms with two well‐characterized examples being Toxoplasma endodyogeny and Plasmodium…”
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Toxoplasma gondii 's Basal Complex: The Other Apicomplexan Business End Is Multifunctional by Gubbels, Marc-Jan, Ferguson, David J P, Saha, Sudeshna, Romano, Julia D, Chavan, Suyog, Primo, Vincent A, Michaud, Cynthia, Coppens, Isabelle, Engelberg, Klemens

“…The Apicomplexa are famously named for their apical complex, a constellation of organelles at their apical end dedicated to invasion of their host cells. In…”
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Migratory activation of parasitized dendritic cells by the protozoan Toxoplasma gondii 14-3-3 protein: Toxoplasma-induced hypermigration of dendritic cells by Weidner, Jessica M., Kanatani, Sachie, Uchtenhagen, Hannes, Varas-Godoy, Manuel, Schulte, Tim, Engelberg, Klemens, Gubbels, Marc-Jan, Sun, He Song, Harrison, Rene E., Achour, Adnane, Barragan, Antonio

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A MORN1-associated HAD phosphatase in the basal complex is essential for Toxoplasma gondii daughter budding: Toxoplasma basal complex HAD phosphatase by Engelberg, Klemens, Ivey, F. Douglas, Lin, Angela, Kono, Maya, Lorestani, Alexander, Faugno-Fusci, Dave, Gilberger, Tim-Wolf, White, Michael, Gubbels, Marc-Jan

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Specific phosphorylation of the PfRh2b invasion ligand of Plasmodium falciparum by Engelberg, Klemens, Paul, Aditya S, Prinz, Boris, Kono, Maya, Ching, Wilhelm, Heincke, Dorothee, Dobner, Thomas, Spielmann, Tobias, Duraisingh, Manoj T, Gilberger, Tim-Wolf

“…Red blood cell invasion by the malaria parasite Plasmodium falciparum relies on a complex protein network that uses low and high affinity receptor-ligand…”
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Plasmodium falciparum possesses two GRASP proteins that are differentially targeted to the Golgi complex via a higher- and lower-eukaryote-like mechanism by Struck, Nicole S, Herrmann, Susann, Langer, Christine, Krueger, Andreas, Foth, Bernardo J, Engelberg, Klemens, Cabrera, Ana L, Haase, Silvia, Treeck, Moritz, Marti, Matthias, Cowman, Alan F, Spielmann, Tobias, Gilberger, Tim W

“…Plasmodium falciparum, the causative agent of malaria, relies on a complex protein-secretion system for protein targeting into numerous subcellular…”
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