Search Results - "Engel, Sven"

Flexible Usage and Interconnectivity of Diverse Cell Death Pathways Protect against Intracellular Infection by Doerflinger, Marcel, Deng, Yexuan, Whitney, Paul, Salvamoser, Ranja, Engel, Sven, Kueh, Andrew J., Tai, Lin, Bachem, Annabell, Gressier, Elise, Geoghegan, Niall D., Wilcox, Stephen, Rogers, Kelly L., Garnham, Alexandra L., Dengler, Michael A., Bader, Stefanie M., Ebert, Gregor, Pearson, Jaclyn S., De Nardo, Dominic, Wang, Nancy, Yang, Chenying, Pereira, Milton, Bryant, Clare E., Strugnell, Richard A., Vince, James E., Pellegrini, Marc, Strasser, Andreas, Bedoui, Sammy, Herold, Marco J.

“…Programmed cell death contributes to host defense against pathogens. To investigate the relative importance of pyroptosis, necroptosis, and apoptosis during…”
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GPR41 and GPR43 regulate CD8 + T cell priming during herpes simplex virus type 1 infection by Lee, Ariane Renita, Wilson, Kayla Roberta, Clarke, Michele, Engel, Sven, Tscharke, David C, Gebhardt, Thomas, Bedoui, Sammy, Bachem, Annabell

“…Naïve CD8 T cells need to undergo a complex and coordinated differentiation program to gain the capacity to control virus infections. This not only involves…”
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CD4+ T cell immunity to Salmonella is transient in the circulation by Peres, Newton G, Wang, Nancy, Whitney, Paul, Engel, Sven, Shreenivas, Meghanashree M, Comerford, Ian, Hocking, Dianna M, Erazo, Anna B, Förster, Irmgard, Kupz, Andreas, Gebhardt, Thomas, McColl, Shaun R, McSorley, Stephen J, Bedoui, Sammy, Strugnell, Richard A

“…While Salmonella enterica is seen as an archetypal facultative intracellular bacterial pathogen where protection is mediated by CD4+ T cells, identifying…”
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Perspectives from Europe region by Lewis, Ben, Engel, Sven H., Bloomfield, John, Moriarty, Paul, Giovannucci, Gian Luca, Melfi, Mariagrazia

“…This article highlights the establishment of development efforts of four different associations to meet the needs of higher education, ministries, and the…”
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CRISPR-Cas9 screening identifies an IRF1-SOCS1-mediated negative feedback loop that limits CXCL9 expression and antitumor immunity by House, Imran G., Derrick, Emily B., Sek, Kevin, Chen, Amanda X.Y., Li, Jasmine, Lai, Junyun, Todd, Kirsten L., Munoz, Isabelle, Michie, Jessica, Chan, Cheok Weng, Huang, Yu-Kuan, Chan, Jack D., Petley, Emma V., Tong, Junming, Nguyen, DatMinh, Engel, Sven, Savas, Peter, Hogg, Simon J., Vervoort, Stephin J., Kearney, Conor J., Burr, Marian L., Lam, Enid Y.N., Gilan, Omer, Bedoui, Sammy, Johnstone, Ricky W., Dawson, Mark A., Loi, Sherene, Darcy, Phillip K., Beavis, Paul A.

“…CXCL9 expression is a strong predictor of response to immune checkpoint blockade therapy. Accordingly, we sought to develop therapeutic strategies to enhance…”
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CRISPR-Cas9 screening identifies an IRF1-SOCS1-mediated negative feedback loop that limits CXCL9 expression and antitumor immunity by House, Imran G., Derrick, Emily B., Sek, Kevin, Chen, Amanda X.Y., Li, Jasmine, Lai, Junyun, Todd, Kirsten L., Munoz, Isabelle, Michie, Jessica, Chan, Cheok Weng, Huang, Yu-Kuan, Chan, Jack D., Petley, Emma V., Tong, Junming, Nguyen, DatMinh, Engel, Sven, Savas, Peter, Hogg, Simon J., Vervoort, Stephin J., Kearney, Conor J., Burr, Marian L., Lam, Enid Y.N., Gilan, Omer, Bedoui, Sammy, Johnstone, Ricky W., Dawson, Mark A., Loi, Sherene, Darcy, Phillip K., Beavis, Paul A.

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Functional flexibility and plasticity in immune control of systemic Salmonella infection by Engel, Sven, Bachem, Annabell, Strugnell, Richard A, Strasser, Andreas, Herold, Marco J, Bedoui, Sammy

“…Immunity to systemic Salmonella infection depends on multiple effector mechanisms. Lymphocyte-derived interferon gamma (IFN-γ) enhances cell-intrinsic…”
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Caspase-2 does not play a critical role in cell death induction and bacterial clearance during Salmonella infection by Engel, Sven, Doerflinger, Marcel, Lee, Ariane R., Strasser, Andreas, Herold, Marco J., Bedoui, Sammy, Bachem, Annabell

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MiR-21 is required for efficient kidney regeneration in fish by Hoppe, Beate, Pietsch, Stefan, Franke, Martin, Engel, Sven, Groth, Marco, Platzer, Matthias, Englert, Christoph

“…Acute kidney injury in mammals, which is caused by cardiovascular diseases or the administration of antibiotics with nephrotoxic side-effects is a…”
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CD4.sup.+ T cell immunity to Salmonella is transient in the circulation by Peres, Newton G, Wang, Nancy, Whitney, Paul, Engel, Sven, Shreenivas, Meghanashree M, Comerford, Ian, Hocking, Dianna M, Erazo, Anna B, Förster, Irmgard, Kupz, Andreas, Gebhardt, Thomas, McColl, Shaun R, McSorley, Stephen J, Bedoui, Sammy, Strugnell, Richard A

“…While Salmonella enterica is seen as an archetypal facultative intracellular bacterial pathogen where protection is mediated by CD4.sup.+ T cells, identifying…”
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CD4+ T cell immunity to Salmonella is transient in the circulation by Newton G Peres, Nancy Wang, Paul Whitney, Sven Engel, Meghanashree M Shreenivas, Ian Comerford, Dianna M Hocking, Anna B Erazo, Irmgard Förster, Andreas Kupz, Thomas Gebhardt, Shaun R McColl, Stephen J McSorley, Sammy Bedoui, Richard A Strugnell

“…While Salmonella enterica is seen as an archetypal facultative intracellular bacterial pathogen where protection is mediated by CD4+ T cells, identifying…”
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On the geometry and trigonometry of homogeneous 3-manifolds with 4-dimensional isometry group by Engel, Sven

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CD4 + T cell immunity against cutaneous melanoma encompasses multifaceted MHC II-dependent responses by Bawden, Emma G, Wagner, Teagan, Schröder, Jan, Effern, Maike, Hinze, Daniel, Newland, Lewis, Attrill, Grace H, Lee, Ariane R, Engel, Sven, Freestone, David, de Lima Moreira, Marcela, Gressier, Elise, McBain, Nathan, Bachem, Annabell, Haque, Ashraful, Dong, Ruining, Ferguson, Angela L, Edwards, Jarem J, Ferguson, Peter M, Scolyer, Richard A, Wilmott, James S, Jewell, Christopher M, Brooks, Andrew G, Gyorki, David E, Palendira, Umaimainthan, Bedoui, Sammy, Waithman, Jason, Hochheiser, Katharina, Hölzel, Michael, Gebhardt, Thomas

“…Whereas CD4 T cells conventionally mediate antitumor immunity by providing help to CD8 T cells, recent clinical studies have implied an important role for…”
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CD4.sup.+ T cell immunity to Salmonella is transient in the circulation by Peres, Newton G, Wang, Nancy, Whitney, Paul, Engel, Sven, Shreenivas, Meghanashree M, Comerford, Ian, Hocking, Dianna M, Erazo, Anna B, Förster, Irmgard, Kupz, Andreas, Gebhardt, Thomas, McColl, Shaun R, McSorley, Stephen J, Bedoui, Sammy, Strugnell, Richard A

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